Cupriethylenediamine

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.

· Wear positive pressure self-contained breathing apparatus (SCBA).

0.01 [mg/m3], respirable fraction (Cu, inorganic cmpnds)[German Research Foundation (DFG)]

If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Solid streams of water may be ineffective. Use "alcohol" foam, dry chemical or carbon dioxide.

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary.

Personnel protection: Avoid breathing vapors. Keep upwind. ... Avoid bodily contact with the material. ... Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water. If contact with the material anticipated, wear appropriate chemical protective clothing.

SRP: Contaminated protective clothing should be segregated in such a manner so that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. Quality assurance to ascertain the completeness of the cleaning procedures should be implemented before the decontaminated protective clothing is returned for reuse by the workers. Contaminated clothing should not be taken home at end of shift, but should remain at employee's place of work for cleaning.

1.0 [mg/m3], as Cu

8 hr Time Weighted Avg (TWA): 1 mg/cu m /Copper dusts and mists, as Cu/

Excursion Limit Recommendation: Excursions in worker exposure levels may exceed 3 times the TLV-TWA for no more than a total of 30 minutes during a work day, and under no circumstances should they exceed 5 times the TLV-TWA, provided that the TLV-TWA is not exceeded. /Copper dusts and mists, as Cu/

People must absorb small amounts of copper every day because copper is essential for good health, however, high levels of copper can be harmful. Very-high doses of copper can cause damage to your liver and kidneys, and can even cause death. Copper may induce allergic responses in sensitive individuals. (L278, L279)

Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes become saturated and copper accumulates in the nucleus, causing nuclear damage. This damage is possibly a result of oxidative damage, including lipid peroxidation. Copper inhibits the sulfhydryl group enzymes such as glucose-6-phosphate 1-dehydrogenase, glutathione reductase, and paraoxonases, which protect the cell from free oxygen radicals. It also influences gene expression and is a co-factor for oxidative enzymes such as cytochrome C oxidase and lysyl oxidase. In addition, the oxidative stress induced by copper is thought to activate acid sphingomyelinase, which lead to the production of ceramide, an apoptotic signal, as well as cause hemolytic anemia. Copper-induced emesis results from stimulation of the vagus nerve. (L277, T49, A174, L280)

STRONG IRRITANT TO TISSUE.

Inhalation of vapor irritates mucous membrane and may cause asthma. Liquid causes severe irritation of eyes and possible corneal injury. Contact with skin causes irritation. Ingestion causes irritation of mouth and stomach. /Cupriethylenediamine hydroxide solution/

Activated sludge from a bench-scale plant was buffered with a borate-HCl buffer at pH 7.5, to prevent copper hydroxide pptn, and incubated with citric and tartaric acid complexes with copper triethanolamine and ethylenediamine 3:1 complexes, a glycine 2:1 complex, and a gluconic acid 1:1 complex. Dehydrogenase activity was determined by the amount of formazan formed by 2,3,5-triphenyltetrazolium chloride reduction. The toxicity threshold was substantially higher for the citric acid-, triethanolamine-, and ethlenediamine-copper complexes than for copper sulfate (0.3 mg/l), probably due to their high stability.

Copper-containing herbicides are often applied to control photoautotrophic populations to reduce biosynthesis of the earthy odorant geosmin. The objective of this investigation was to determine the effects of copper-containing herbicides on geosmin and biomass biosynthesis by heterotrophic cultures of the bacterium Streptomyces tendae and the fungus Penicillium expansum. Inductively coupled plasma atomic emission spectrometry of S. tendae of untreated control cultures indicated that cellular copper concentrations were below 0.5 mg Cu kg-1. However, S. tendae cells grown on a medium containing 5 mg Cu L-1 copper sulfate contained 12.88 : 0.54 mg Cu kg-1, suggesting that cellular accumulation of copper may be associated with increased geosmin biosynthesis. If field microbial populations exhibit similar responses to copper, copper-algicide application may contribute to geosmin-induced "off-flavors" under certain circumstances. Nomenclature: Geosmin, 1alpha,10beta-dimethyl-9alpha-decalol; copper sulfate, cupric sulfate pentahydrate; copper chelate, copper II alkanolamine complex; copper chloride, cupric chloride hexahydrate.

As the federal pesticide law FIFRA directs, EPA is conducting a comprehensive review of older pesticides to consider their health and environmental effects and make decisions about their future use. Under this pesticide reregistration program, EPA examines health and safety data for pesticide active ingredients initially registered before November 1, 1984, and determines whether they are eligible for reregistration. In addition, all pesticides must meet the new safety standard of the Food Quality Protection Act of 1996. Pesticides for which EPA had not issued Registration Standards prior to the effective date of FIFRA, as amended in 1988, were divided into three lists based upon their potential for human exposure and other factors, with List B containing pesticides of greater concern and List D pesticides of less concern. Copper as elemental from copper - ethylenediamine complex is found on List D. Case No: 4026; Pesticide type: Fungicide, molluscicide; Case Status: OPP is reviewing data from the pesticide's producers regarding its human health and/or environmental effects, or OPP is determining the pesticide's eligibility for reregistration and developing the Reregistration Eligibility Decision (RED) document.; Active ingredient (AI): Copper as elemental from copper - ethylenediamine complex; Data Call-in (DCI) Date(s): 10/06/93, 05/18/95; AI Status: The producers of the pesticide has made commitments to conduct the studies and pay the fees required for reregistration, and are meeting those commitments in a timely manner.

Used as a cellulose and cotton solvent; Older pesticide: fungicide and molluscicide; [HSDB] Classified as a herbicide and agricultural chemical; [ChemIDplus] Used to dissolve cellulose products; [NJ-HSFS]

Textiles (Fiber & Fabric Manufacturing) [Category: Industry]

For Cupriethylenediamine (USEPA/OPP Pesticide Code: 024407) ACTIVE products with label matches. /SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./

Cellulose solvent /Cupriethylenediamine hydroxide/

Cotton solvent /Cupriethylenediamine hydroxide/