(4α,8α,9β,13α,14β,17Z)-16β-Acetoxy-3α,11α-dihydroxy-29-nordammara-17(20),24-dien-21-sure, Verbindung mit 2,2'-Iminodiethanol (1:1)
29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, (3alpha,4alpha,8alpha,9beta,11alpha,13alpha,14beta,16beta,17Z)-, compd. with 2,2'-iminobis(ethanol) (1:1)
Grundinformationen
- CAS
16391-75-6- Standard-SMILES
CC(=O)O[C@H]1C[C@@]2(C)[C@@H](C[C@@H](O)[C@H]3[C@@]4(C)CC[C@@H](O)[C@@H](C)[C@@H]4CC[C@@]32C)/C1=C(\CCC=C(C)C)C(=O)O.OCCNCCO- InChIKey
OQZZCXRLEFBPLZ-JCJNLNMISA-N- Summenformel
- C35H59NO8
- Durchschnittliche Molmasse
- 621,8 g/mol
- Monoisotopische Masse
- 621,42406784
Namen und Bezeichner
- Bevorzugter Name
- 29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, (3alpha,4alpha,8alpha,9beta,11alpha,13alpha,14beta,16beta,17Z)-, compd. with 2,2'-iminobis(ethanol) (1:1)
- IUPAC
- (2Z)-2-[(3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetyloxy-3,11-dihydroxy-4,8,10,14-tetramethyl-2,3,4,5,6,7,9,11,12,13,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ylidene]-6-methylhept-5-enoic acid;2-(2-hydroxyethylamino)ethanol
- Lokaler Name
- (4α,8α,9β,13α,14β,17Z)-16β-Acetoxy-3α,11α-dihydroxy-29-nordammara-17(20),24-dien-21-sure, Verbindung mit 2,2'-Iminodiethanol (1:1)
- Englischer Name
- Diethanolamine Fusidate
- Summenformel
- C35H59NO8
- Molmasse
- 621.86
Namen und Synonyme
Diethanolamine fusidate16391-75-61XKK7J9CT6DTXSID701020012RefChem:586945DTXCID801477862(3 alpha,8 alpha,9 beta,13 alpha,14 beta,16 beta,17(Z))-16-(acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid, compd. with 2,2'-iminobis(ethanol) (1:1)240-442-3Fucidin (TN)Fusidic acid diolamineFUSIDATE DIOLAMINEFUSIDATE DIETHANOLAMINE
Weitere Namen anzeigen
Fusidic Acid Impurity 18Sodium Fusidate Impurity 182,2'-IMinobis(ethanol) (3,4α,8α,9β,11α,13α,14β,16β,17Z)-16-(acetyloxy)- 3,11-dihydroxy-29-(3α,4α,8α,9β,11α,13α,14β,16β,17Z)-16-(acetyloxy)-3,11-dihydroxy29-Nordammara-17(20),24-dien-21-oic acid, 2,2′-iminobis[ethanol](1:1)(3,4α,8α,9β,11α,13α,14β,16β,17Z)-16-(Acetyloxy)-3,11-dihydroxy-29-nordaMMara-17(20),24-dien-21-oic Acid coMpd. with 2,2'-IMinobis[ethanol]
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 157 Ų
- H-Brücken-Donoren
- 6
- H-Brücken-Akzeptoren
- 9
- Frei drehbare Bindungen
- 10
- Schwere Atome
- 44
- Formalladung
- 0
- Komplexität
- 1.020
Experimentelle und physikochemische Eigenschaften
Human DrugsBreast Feeding; Lactation; Milk, Human; Antibacterial Agents; Anti-Infective Agents; Protein Synthesis Inhibitors
Animal DrugsPharmaceuticals -> UK Veterinary Medicines Directorate List
Physikochemische Eigenschaften
- Schmelzpunkt
- 96 · 96 - 100°C
- storage temp.
- Hygroscopic, Refrigerator, Under Inert Atmosphere
- Löslichkeit
- Chloroform (Sparingly), DMSO (Slightly, Heated), Methanol (Slightly)
- Aggregatzustand
- Solid
- Farbe
- Off-White to Pale Yellow
- Stabilität
- Hygroscopic
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 2 reports by companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Regulatory Information
29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, (3.alpha.,4.alpha.,8.alpha.,9.beta.,11.alpha.,13.alpha.,14.beta.,16.beta.,17Z)-, compd. with 2,2'-iminobis[ethanol] (1:1): Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Other Safety Information
IMAP assessments - 29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, (3.alpha.,4.alpha.,8.alpha.,9.beta.,11.alpha.,13.alpha.,14.beta.,16.beta.,17Z)-, compound with 2,2'-iminobis[ethanol] (1:1): Environment tier I assessment
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Toxikologische Informationen
Effects During Pregnancy and Lactation◉ Summary of Use during Lactation
Sicherheitsdaten
Chemie und Industrie
Anwendungen
VerwendenA bacteriostatic antibiotic with similar activity and better absorption after oral administration (in animals) than the sodium salt of Fusidic Acid (F865500). Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA.
Anbieter40 Anbieter
湖北万得化工有限公司15377098680 15377098680 · [email protected]
济南百隆化学有限公司[email protected] · [email protected]
艾吉析科技（上海）有限公司17717235263 · [email protected]
武汉卓元易创科技有限公司13476791851 13476791851 · [email protected]
广州隽沐生物科技股份有限公司020-36607679; 13502246435 · [email protected]
陕西缔都新材料有限公司029-63373950 17392216152 · [email protected]
广州隽唐科技有限公司020-36607679 13502246435 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
廊坊市恒福源医药科技有限公司0316-2883537 19333636468 · [email protected]
希瓦生物科技（广州）有限公司13268215580 · [email protected]
上海柯维化学技术有限公司021-64609169 18901607656 · [email protected]
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