Grundinformationen
- CAS
370-14-9- Standard-SMILES
CNC(C)Cc1ccc(O)cc1- InChIKey
SBUQZKJEOOQSBV-UHFFFAOYSA-N- Summenformel
- C10H15NO
- Durchschnittliche Molmasse
- 165,23 g/mol
- Monoisotopische Masse
- 165,1153641
Überblick
Pholedrine is a member of amphetamines.
Namen und Bezeichner
- Bevorzugter Name
- (+-)-Pholedrine
- IUPAC
- 4-[2-(methylamino)propyl]phenol
- Lokaler Name
- Pholedrin
- Englischer Name
- p-Hydroxymethamphetamine
- Summenformel
- C10H15NO
- Molmasse
- 165.23
Namen und Synonyme
PholedrineIsodrinePulsotylPressitan370-14-9Racemic pholedrinePholedrinum4-Hydroxy-N-methylamphetaminep-(2-Methylaminopropyl)phenolIsodrin (sympathomimetic)Oh-ma1-(p-Hydroxyphenyl)-2-methylaminopropane
Weitere Namen anzeigen
epifenvaritolVeritolfoledrinknollh75prometinveritainisodrinum
p-Hydroxy-N-methylamphetamineFoledrinap-Hydroxy-N,alpha-dimethylphenethylaminebeta-(p-Hydroxyphenyl)isopropylmethylamineKNOLL-H75PHENOL, p-(2-(METHYLAMINO)PROPYL)-AY28O44JGDalpha-(p-Hydroxyphenyl)-beta-methylaminopropane
Datenbank-Bezeichner
- CAS
370-14-9- PubChem CID
- 4655
- DTXSID
DTXSID70861908- ChEMBL
CHEMBL2008672- ChEBI
CHEBI:134798
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 1,7
- Polarare Oberfläche (TPSA)
- 32,3 Ų
- H-Brücken-Donoren
- 2
- H-Brücken-Akzeptoren
- 2
- Frei drehbare Bindungen
- 3
- Schwere Atome
- 12
- Formalladung
- 0
- Komplexität
- 119
Experimentelle und physikochemische Eigenschaften
Human DrugsPharmaceuticals
Physikochemische Eigenschaften
- Schmelzpunkt
- 162 · 162-163°
- Siedepunkt
- 293.09 °C · 293.09°C (rough estimate)
- Dichte
- 1.0203 · 1.0203 (rough estimate)
- Brechungsindex
- 1.482 · 1.4820 (estimate)
- storage temp.
- 20 °C · −20°C
- Löslichkeit
- Methanol (Slightly)
- pka
- 9.82 · 9.82±0.15(Predicted)
- Major Application
- forensics and toxicologypharmaceutical (small molecule)veterinary
- InChI
- 1S/C10H15NO/c1-8(11-2)7-9-3-5-10(12)6-4-9/h3-6,8,11-12H,7H2,1-2H3
- InChIKey
- SBUQZKJEOOQSBV-UHFFFAOYSA-N
- SMILES
- CNC(C)Cc1ccc(O)cc1
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Sicherheitsdaten
- wgk
- 3
- RTECS-Nr.
- SL8400000
- risk_code
- 36/37/38-39/23/24/25-23/24/25-11
- Toxizität
- LD50 parenteral in mouse: 100mg/kg
- hazard_code
- Xi,T,F
- safety_code
- 26-36-45-36/37-16-7
- Speicherklasse
- 11 - Combustible Solids
- Hazard Classifications
- Eye Irrit. 2Skin Irrit. 2STOT SE 3
Chemie und Industrie
Pharmakologische Informationen
Metabolism/MetabolitesHO-MA is a known human metabolite of p-Methoxymethamphetamine, R-(-)-.
MeSH Pharmacological Classification
A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here.
Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
Tissue LocationsKidney
Cellular LocationsCytoplasm
Verwendung und Herstellung
Use ClassificationPharmaceuticals
Vor- und nachgelagerte Produkte
Vorgelagerte Rohstoffe
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