HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HCID 4742004Erstellt: 23. Oktober 2026
1-Cyclopropylpiperazine
Cyclopropyl piperazine · N-cyclopropylpiperazine · 1-Cyclopropylpiperazine · Piperazine,1-cyclopropyl- · 1-Cyclopropylpiperazine >(Piperazin-1-yl)cyclopropane · 1-(Cyclopropyl Phenyl)Piperazine · 1-Cyclopropylpiperazine - [C14363] · 1-Cyclopropylpiperazine ISO 9001：2015 REACH
https://huagongshe.com/de/chemical/4742004
Identifikatoren & physikalische Daten
| CAS No. | 20327-23-5 |
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| Summenformel | C7H14N2 |
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| Durchschnittliche Molmasse | 126,2 g/mol |
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| Monoisotopische Masse | 126,11569845 g/mol |
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| SMILES | C1CN(C2CC2)CCN1 |
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| InChIKey | HNZJIWIXRPBFAN-UHFFFAOYSA-N |
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| PubChem CID | 4742004 |
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| EC No. | 807-993-7 |
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| DTXSID | DTXSID20406303 |
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Chemische & physikalische Eigenschaften
| XLogP | 0,2 |
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| Polarare Oberfläche (TPSA) | 15,3 |
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| H-Brücken-Donoren | 1 |
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| H-Brücken-Akzeptoren | 2 |
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| Frei drehbare Bindungen | 1 |
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| Schwere Atome | 9 |
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| Formalladung | 0 |
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| Komplexität | 93,1 |
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| Siedepunkt | 43°C/7mm |
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| Dichte | 0.94 |
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| Brechungsindex | 1.4804 |
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| Lagerbedingungen | Keep in dark place,Sealed in dry,Room Temperature |
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| Aggregatzustand | clear liquid |
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| pKa (Säurekonstante) | 9.23±0.10(Predicted) |
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| Farbe | Colorless to Light yellow |
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| InChI | InChI=1S/C7H14N2/c1-2-7(1)9-5-3-8-4-6-9/h7-8H,1-6H2 |
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| InChIKey | HNZJIWIXRPBFAN-UHFFFAOYSA-N |
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| SMILES | N1(C2CC2)CCNCC1 |
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Sicherheit & Vorschriften
| GHS-Einstufung | DangerH302 (60%): Harmful if swallowed [Warning Acute toxicity, oral]P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 5 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
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| Hazard Classes and Categories | Acute Tox. 4 (60%) |
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| UN-Transportnummer | 3267 |
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| Zollcode | 2933599590 |
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| Gefahrensymbole | Xi |
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| Gefahrenklasse | 8 |
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| Verpackungsgruppe | Ⅲ |
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Anwendungen & Verwendung
Verwenden
1-cyclopropylpiperazine is a piperazine derivative known in the literature by synonyms such as N-cyclopropylpiperazine and 4-cyclopropylpiperazine. It has been used in the preparation of some tri- and tetrasubstituted ureas with histamine H3 antagonist receptor activity, 3-amido-4- anilinoquinolines series as CSF-1R kinase inhibitors, for the synthesis of cyclopropyl amines as modulators of the histamine H3 receptor, sulfonamide compounds as cysteine protease inhibitors, N-oxides as antibacterial agents and in the treatment of the disease caused by helicobacter infection[1].
