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Phenolrot
PR · PHENOLSULFONPHTHALEIN · phenolsulphonphthalein · A-HYDROXY-A A-BIS(P-HYDROXYPHENYL)-O-TOLUENESULFONIC ACID G-SULTONE · PRGR · NR3C3 · P3532-5G · Phenolrde
Identifikatoren & physikalische Daten
| CAS No. | 143-74-8 |
|---|---|
| Summenformel | C19H14O5S |
| Durchschnittliche Molmasse | 354,4 g/mol |
| Monoisotopische Masse | 354,05619455 g/mol |
| SMILES | O=S1(=O)OC(c2ccc(O)cc2)(c2ccc(O)cc2)c2ccccc21 |
| InChIKey | BELBBZDIHDAJOR-UHFFFAOYSA-N |
| PubChem CID | 4766 |
| ChEMBL | CHEMBL258921 |
| ChEBI | CHEBI:31991 |
| EC No. | 205-609-7 |
| DTXSID | DTXSID8022408 |
| Lokaler Name | Phenolrot |
Chemische & physikalische Eigenschaften
| XLogP | 3 |
|---|---|
| Polarare Oberfläche (TPSA) | 92,2 |
| H-Brücken-Donoren | 2 |
| H-Brücken-Akzeptoren | 5 |
| Frei drehbare Bindungen | 2 |
| Schwere Atome | 25 |
| Formalladung | 0 |
| Komplexität | 545 |
| Stoffklassen | Dyes -> Indicator Dyes |
| LogP (Verteilungskoeffizient) | 3.02 |
| Animal Drugs | Pharmaceuticals -> UK Veterinary Medicines Directorate List |
| Endocrine Disruptors | Potential endocrine disrupting compound |
| Physical Description | Odorless, red solidAvailable as pure compound, soluble monosodium salt, and dilute solutions[CHEMINFO] |
| Collision Cross Section | 179.8 Ų [M+H]+ [CCS Type: DTBuffer gas: N2Ionization: ESI+Dataset: TOXCASTSource Identifier: DTXSID2044420] |
| Schmelzpunkt | >300 °C |
| Siedepunkt | >300°C |
| Dichte | 1.445 Mg m-3 |
| Brechungsindex | 1.5300 (estimate) |
| Flammpunkt | >300°C |
| Lagerbedingungen | no restrictions. |
| Löslichkeit | 1 M NaOH: soluble1mg/mL0.77 g/L |
| Aggregatzustand | Solid |
| pKa (Säurekonstante) | 7.9(at 25℃) |
| Farbe | Red |
| Geruch | Odorless |
| pH | 6.8~8.4 |
| Merck | 14,7247 |
| BRN | 326470 |
| Hauptanwendungen | Display device, sol-gel matrix, photoreceptors, fuel cells, waveguides, paints, detergents, cosmetics, antiperspirant composition, diapers, screening bacteria, detecting viable cells, diagnosis of urogenital ureaplasmosis, treatment of pathogen infections, amyloid-associated diseases, glaucoma, pulmonary hypertension, asthma, chronic obstructive pulmonary disease, erectile dysfunction, Raynaud’s syndrome, heparin overdose, vulvodynia, wound healing, psychoactive drugs, evaluating dental caries activity |
| Kosmetik-Inhaltsstoffe Funktionen | BUFFERING |
| InChI | 1S/C19H14O5S/c20-15-9-5-13(6-10-15)19(14-7-11-16(21)12-8-14)17-3-1-2-4-18(17)25(22,23)24-19/h1-12,20-21H |
| InChIKey | BELBBZDIHDAJOR-UHFFFAOYSA-N |
| LogP (Verteilungskoeffizient) | 3.020 |
| CAS Datenbank | 143-74-8(CAS DataBase Reference) |
| EPA chemische Informationen | Phenol Red (143-74-8) |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 1.4% (3 of 211) of reports.WarningH315 (98.6%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 211 reports by companies from 15 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | Chemical: Phenol, 4,4'-(3H-2,1-benzoxathiol-3-ylidene)bis-, S,S-dioxidePhenolsulfonphthalein: Does not have an individual approval but may be used under an appropriate group standard |
| Gefahrenübersicht | Dust may be irritating if inhaled[CHEMINFO] |
| Hazard Classes and Categories | Skin Irrit. 2 (98.6%) |
| Wassergefährdungsklasse (WGK) | 3 |
| TSCA-Inventar-Status | TSCA listed |
| Zollcode | 29349990 |
| RTECS-Nr. | SJ7490000 |
| R-Sätze (R) | 36/37/38-34 |
| Toxizität | LD50 orl-rat: >600 mg/kg CTOXAO 4(2),185,71 |
| Gefahrensymbole | Xi,C |
| Sicherheitshinweise (S) | 37/39-26-45-36/37/39-27 |
| Lagerklasse | 11 - Combustible Solids |
| Gefahrenklasse | Skin Irrit. 2STOT SE 3 |
Anwendungen & Verwendung
Beschreibung
Phenol red belongs to the class of triphenylmethane dyes and is widely used in the textile industry.
Verwenden
Phenol red is used as a non absorbed marker in gravimetric method. It is a pH indicator used in cell biology laboratories and in home swimming pool test kits. It is used to check the kidney function based on the excreted phenol red by colorimetric method.
Herstellung & Synthese
synthetische
Phenol red is prepared in Dulbecco′s Phosphate Buffered Saline.