Phenylarsinoxid

Polyalphaolefins · PAO · ARZENE · Poly α-olefins · fenylarsinoxid · OXOPHENYLARSINE · Arsenosobenzene · arsenoso-benzen

Identifikatoren & physikalische Daten

CAS No.	637-03-6
Summenformel	C6H5AsO
Durchschnittliche Molmasse	168,02 g/mol
Monoisotopische Masse	167,95563628 g/mol
SMILES	O=[As]c1ccccc1
InChIKey	BQVCCPGCDUSGOE-UHFFFAOYSA-N
PubChem CID	4778
ChEMBL	CHEMBL477683
ChEBI	CHEBI:75253
EC No.	211-275-3
DTXSID	DTXSID5042249
Lokaler Name	Phenylarsinoxid

Chemische & physikalische Eigenschaften

Polarare Oberfläche (TPSA)	17,1
H-Brücken-Donoren	0
H-Brücken-Akzeptoren	1
Frei drehbare Bindungen	0
Schwere Atome	8
Formalladung	0
Komplexität	76,6
Stoffklassen	Metals -> Arsenic Compounds, Organic
Physical Description	Crystals with a melting point of 144-146 degrees C[Merck Index]
Schmelzpunkt	145-148 °C
Lagerbedingungen	Poison room
Löslichkeit	DMSO: 50 mg/mLSoluble in dimethyl sulfoxide, chloroform, benzene, ether, ethanol, 50:50 dimethyl sulfoxide:1 M hydrochloric acid (3.0 mg/ml) and toluene. Insoluble in water.
Aggregatzustand	powder
Farbe	white to yellow
Biologische Quelle	synthetic (organic)
Merck	14,6949
BRN	2935227
Henry-Konstante	9.0×10-1 mol/(m3Pa) at 25℃, Bartelt-Hunt et al. (2008)
Stabilität	Stable.
InChI	InChI=1S/C6H5AsO/c8-7-6-4-2-1-3-5-6/h1-5H
InChIKey	BQVCCPGCDUSGOE-UHFFFAOYSA-N
SMILES	[As](=O)C1=CC=CC=C1
CAS Datenbank	637-03-6(CAS DataBase Reference)
EPA chemische Informationen	Oxophenylarsine (637-03-6)

Sicherheit & Vorschriften

GHS-Einstufung	DangerH301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]P261, P264, P270, P271, P273, P301+P316, P304+P340, P316, P321, P330, P391, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 48 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Regulatorische Informationen	Chemical: Arsine, oxophenyl-Restricted substance: Phenylarsine oxide
Gefahrenübersicht	Acute or chronic arsenic poisoning may result from ingestion or inhalation of a sufficient dose[MSDSonline] Not found in any pesticide products[NPIRS] Almost nothing is known regarding health effects of organic arsenic compounds in humans. Studies in animals show that some simple organic arsenic compounds are less toxic than inorganic forms. Ingestion of methyl and dimethyl compounds can cause diarrhea and damage to the kidneys. [ATSDR ToxProfiles]
Hazard Classes and Categories	Acute Tox. 3 (100%)
Expositionsschutz und Persönliche Schutzausrüstung	TIH (Toxic Inhalation Hazard) - Term used to describe gases and volatile liquids that are toxic when inhaled. Some are TIH materials themselves, e.g., chlorine, and some release TIH gases when spilled in water, e.g., chlorosilanes. [ERG 2016].
Permissible Exposure Limit (PEL)	0.5 [mg/m3], as As
Wassergefährdungsklasse (WGK)	3
TSCA-Inventar-Status	TSCA listed
UN-Transportnummer	UN 3465 6.1/PG 3
Zollcode	29310099
RTECS-Nr.	CH8100000
R-Sätze (R)	23/25-50/53
Toxizität	LD50 ipr-mus: 1930 mg/kg JPETAB 74,210,42
Gefahrensymbole	T,N
Sicherheitshinweise (S)	20/21-28-45-60-61
Gefahrenklasse	6.1Acute Tox. 3 InhalationAcute Tox. 3 OralAquatic Acute 1Aquatic Chronic 1
Verpackungsgruppe	III
Lagerklasse	6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects

Anwendungen & Verwendung

Verwenden

Phenylarsine oxide is used as a poultry coccidiostat in veterinary medicine. It is also used in a membrane-permeable protein tyrosine phosphatase inhibitor.