Cholest-5-en-3β-ylhydrogensuccinat

4-[[17-(1,5-dimethylhexyl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-4-oxo-butanoic acid

HCID 500055CAS 1510-21-0
TeilstruktursucheÄhnliche Strukturen suchen

Grundinformationen

Standard-SMILES
CC(C)CCCC(C)C1CCC2C3CC=C4CC(OC(=O)CCC(=O)O)CCC4(C)C3CCC12C
InChIKey
WLNARFZDISHUGS-UHFFFAOYSA-N
Summenformel
C31H50O4
Durchschnittliche Molmasse
486,7 g/mol

Namen und Bezeichner

Bevorzugter Name
4-[[17-(1,5-dimethylhexyl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-4-oxo-butanoic acid
IUPAC
4-[[10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-4-oxobutanoic acid
Lokaler Name
Cholest-5-en-3β-ylhydrogensuccinat
Englischer Name
Cholesteryl hemisuccinate
Summenformel
C31H50O4
Molmasse
486.73

Namen und Synonyme

4-(Cholest-5-en-3-yloxy)-4-oxobutanoic acid4-[[17-(1,5-dimethylhexyl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-4-oxo-butanoic acidNSC628321SCHEMBL463416orb3033164AKOS0243195204-[[10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-4-oxobutanoic acidLS-15319DB-043075CHOLESTERYL HYDROGEN SUCCINATEcholesterylsuccinateCholesterol Succinate
Weitere Namen anzeigen
Cholesteryl hemisucciteCHOLESTERYL HEMISUCCINATEMONO-CHOLESTERYL-SUCCINATECHOLESTEROL HYDROGEN SUCCINATE5-CHOLESTEN-3β-OL HEMISUCCINATECholesterol Hydrogen Succinate >5-CHOLESTEN-3-BETA-OL HEMISUCCINATE

Datenbank-Bezeichner

CAS
1510-21-0
PubChem CID
500055

Eigenschaften

Berechnete Struktureigenschaften

XLogP
8,5
Polarare Oberfläche (TPSA)
63,6 Ų
H-Brücken-Donoren
1
H-Brücken-Akzeptoren
4
Frei drehbare Bindungen
10
Schwere Atome
35

Physikochemische Eigenschaften

Schmelzpunkt
178 °C · 178 °C
Siedepunkt
586 · 586.0±43.0 °C(Predicted)
Dichte
1.06 · 1.06±0.1 g/cm3(Predicted)
Brechungsindex
-34 ° · -34 ° (C=2, CHCl3)
storage temp.
-20 °C · -20°C
Löslichkeit
Chloroform (Slightly), Methanol (Slightly, Heated, Sonicated)

Sicherheit und Regulatorisches

Sicherheitsdaten

wgk
3
hs_code
29171900
Speicherklasse
11 - Combustible Solids

Chemie und Industrie

Anwendungen · 2 Einträge

BeschreibungCholesteryl hemisuccinate is a cholesterol ester with anticancer activity. It inhibits the growth of murine C1498 myeloid and L1210 lymphocytic leukemia cells when used at concentrations of 50 and 150 μM, respectively. Cholesteryl hemisuccinate acts as an ionizable anionic detergent and is commonly used to stabilize unilamellar vesicles and liposomes. It has also been used as an emulsifying agent in various vesicular drug delivery systems for anticancer drugs, antibiotics, and oligonucleotides and to solubilize various proteins including chemokine receptor 1 as well as erythrocyte ghosts.

VerwendenCholesteryl Hemisuccinate is an oxidation product of polyunsaturated fatty acid of cholesterol that alters lysosome structure and functions and induces proinflammatory cytokine production in macrophages.

Vor- und nachgelagerte Produkte

Anbieter50 Anbieter

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
韶远科技(上海)有限公司021-50795510 4000665055 · [email protected]
湖南韵邦生物科技股份有限公司85561037 15386497078 · [email protected]
上海优宁维生物科技股份有限公司15921930842 15921930842 · [email protected]

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