HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
7-[3,5-Dihydroxy-2-(3-hydroxy-4-thiophen-3-yloxybut-1-enyl)cyclopentyl]hept-5-enoic acid
Iliren · Tiaprost · Tiaprost(Iliren) · Tiaprost Exclusive · FYBFDIIAPRHIQS-JRSBLEPXSA-N · 7-[3,5-Dihydroxy-2-[3-hydroxy-4-(3-thienyloxy)-1-butenyl]cyclopentyl]-5-heptenoic acid · 5-Heptenoic acid,7-[3,5-dihydroxy-2-[3-hydroxy-4-(3-thienyloxy)-1-butenyl]cyclopentyl]- · 5-Heptenoic acid, 7-[3,5-dihydroxy-2-[3-hydroxy-4-(3-thienyloxy)-1-buten-1-yl]cyclopentyl]-
![Molekülstruktur von 7-[3,5-Dihydroxy-2-(3-hydroxy-4-thiophen-3-yloxybut-1-enyl)cyclopentyl]hept-5-enoic acid](/img/chemical/51249.png)
Identifikatoren & physikalische Daten
| CAS No. | 71116-82-0 |
|---|---|
| Summenformel | C20H28O6S |
| Durchschnittliche Molmasse | 396,5 g/mol |
| Monoisotopische Masse | 396,16065978 g/mol |
| SMILES | O=C(O)CCCC=CCC1C(O)CC(O)C1C=CC(O)COc1ccsc1 |
| InChIKey | FYBFDIIAPRHIQS-UHFFFAOYSA-N |
| PubChem CID | 51249 |
Chemische & physikalische Eigenschaften
| XLogP | 1,7 |
|---|---|
| Polarare Oberfläche (TPSA) | 135 |
| H-Brücken-Donoren | 4 |
| H-Brücken-Akzeptoren | 7 |
| Frei drehbare Bindungen | 11 |
| Schwere Atome | 27 |
| Formalladung | 0 |
| Komplexität | 509 |
| Siedepunkt | 613.4±55.0 °C(Predicted) |
| Dichte | 1.325±0.06 g/cm3(Predicted) |
| Lagerbedingungen | Store at -20°C |
| Löslichkeit | DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 2 mg/ml |
| Aggregatzustand | Liquid |
| pKa (Säurekonstante) | 4.79±0.10(Predicted) |
| Farbe | Colorless to light yellow |
Sicherheit & Vorschriften
| UN-Transportnummer | 3249 |
|---|---|
| Gefahrenklasse | 6.1(b) |
| Verpackungsgruppe | III |
Anwendungen & Verwendung
Verwenden
Prostaglandin F2α plays a central role in luteolysis. Tiaprost is a synthetic analog of PGF2α that is used in veterinary medicine as an estrus-synchronizing agent. It has also been used to treat endometritis and to induce parturition.[Cayman Chemical]