Lauramidopropyl Dimethylamine (HCID 51392)

Überblick

The CIR Expert Panel concluded that the 24 fatty acid amidopropyl dimethylamines ingredients listed below are safe in cosmetics when they are formulated to be non-sensitizing, which may be based on a QRA...Lauramidopropyl Dimethylamine...

Namen und Bezeichner

Bevorzugter Name: Lauramidopropyl Dimethylamine
IUPAC: N-[3-(dimethylamino)propyl]dodecanamide
Lokaler Name: N-[3-(Dimethylamino)propyl]dodecanamid
Englischer Name: N-[3-(DIMETHYLAMINO)PROPYL]LAURAMIDE
Summenformel: C17H36N2O
Molmasse: 284.48

Namen und Synonyme

N-[3-(dimethylamino)propyl]dodecanamideLauramidopropyl dimethylamineN-[3-(Dimethylamino)propyl]lauramideN-(3-(Dimethylamino)propyl)dodecanamideSCHERCODINE LDodecanamide, N-[3-(dimethylamino)propyl]-(LAURYLAMIDOPROPYL)DIMETHYLAMINEDTXSID8044913FS588RR72JDodecanamide, N-(3-(dimethylamino)propyl)-NSC-79892ZOHAR AMIDO AMINE L

Weitere Namen anzeigen

Lexamine L 13PKO12Einecs 221-661-3Dimethylaminopropyl lauramideLaurylamidopropylDimethylAmineN,N-DimethyllauramidopropylamineLauric 3-dimethylaminopropylamideDodecanoylamidopropyldimethylamineLauroyl(dimethyl amino propyl)amine

3-dodecanamidopropyldimethylamineDTXCID6024913DIMETHYLAMINOPROPYLLAURYLAMIDEN-(3-(Dimethylamino)propyl)lauramide1147459-12-8N,N-DIMETHYLAMINOPROPYLDODECYLAMIDEAmides, C12-18, N-(3-(dimethylamino)propyl)Amides, C12-18, N-[3-(dimethylamino)propyl]

Datenbank-Bezeichner

CAS: 1147459-12-8、3179-80-4
PubChem CID: 51392
DTXSID: DTXSID8044913
ChEMBL: CHEMBL3185963
UNII: FS588RR72J
EC Number: 221-661-3、689-272-5
Nikkaji: J27.687A

Eigenschaften

Berechnete Struktureigenschaften

XLogP: 5,1
Polarare Oberfläche (TPSA): 32,3 Å²
H-Brücken-Donoren: 1
H-Brücken-Akzeptoren: 2
Frei drehbare Bindungen: 14
Schwere Atome: 20
Formalladung: 0
Komplexität: 217

Experimentelle und physikochemische Eigenschaften

Cosmetics · 3 Einträge

Cosmetic ingredients (Lauramidopropyl Dimethylamine) -> CIR (Cosmetic Ingredient Review)

Personal care product

Antistatic

Physical DescriptionLiquid; Other Solid; CBI

Collision Cross Section181.8 Å² [M+Na]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID8044913]

Physikochemische Eigenschaften

Schmelzpunkt: 34.5 · 34.5-38.5 °C(lit.)
Siedepunkt: 171 · 171-194 °C(Press: 2 Torr)
Dichte: 0.882 · 0.882±0.06 g/cm3(Predicted)
Flammpunkt: 230 °F · >230 °F
Löslichkeit: Chloroform (Slightly), Methanol (Slightly)
pka: 16.29 · 16.29±0.46(Predicted)
Aggregatzustand: Low-Melting Solid
Farbe: White to Off-White
Kosmetik-Inhaltsstoffe Funktionen: ANTISTATIC
InChI: InChI=1S/C17H36N2O/c1-4-5-6-7-8-9-10-11-12-14-17(20)18-15-13-16-19(2)3/h4-16H2,1-3H3,(H,18,20)
InChIKey: TWMFGCHRALXDAR-UHFFFAOYSA-N
SMILES: C(NCCCN(C)C)(=O)CCCCCCCCCCC
LogP: 4.561 · 4.561 (est)
Oberflächenspannung: 27.8 mN/m · 27.8mN/m at 1g/L and 20℃
EPA chemische Informationen: 3 · Dodecanamide, N-[3-(dimethylamino)propyl]- (3179-80-4)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

This chemical does not meet GHS hazard criteria for 0.2% (1 of 653) of reports.

Danger

H302 (25.7%): Harmful if swallowed [Warning Acute toxicity, oral]

P260, P261, P264, P264+P265, P270, P272, P273, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P332+P317, P333+P317, P362+P364, P363, P391, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 653 reports by companies from 13 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

Gefahrenhinweise

Regulatory Information · 4 Einträge

Chemical: Dodecanamide, N-[3-(dimethylamino)propyl]-

Dodecanamide, N-[3-(dimethylamino)propyl]- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Dodecanamide, N-[3-(dimethylamino)propyl]- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 23-02-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/10713

Dodecanamide, N-3-(dimethylamino)propyl-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Other Safety InformationIMAP assessments - Fatty acid amido propyl dimethylamines: Human health tier II assessment

Hazard Classes and Categories · 3 Einträge

Acute Tox. 4 (25.7%)

Acute Tox. 4 (100%)

Skin corrosion - category 1

Toxikologische Informationen

Toxicity Summary · 2 Einträge

The CIR Expert Panel concluded that the 24 fatty acid amidopropyl dimethylamines ingredients listed below are safe in cosmetics when they are formulated to be non-sensitizing, which may be based on a QRA...Lauramidopropyl Dimethylamine...

Safe for use in cosmetics, with qualifications

Sicherheitsdaten

wgk: 2
tsca: TSCA listed
risk_code: 36/37/38
hazard_code: Xi
safety_code: 26
Speicherklasse: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2Skin Irrit. 2STOT SE 3

Chemie und Industrie

Verwendung und Herstellung

UsesCIR ingredient: Lauramidopropyl Dimethylamine

U.S. Production2023: 10,000,000 - <25,000,000 lb

Industry UsesIntermediate

Use ClassificationCosmetics -> Antistatic

General Manufacturing Information · 2 Einträge

All Other Basic Organic Chemical Manufacturing

Dodecanamide, N-[3-(dimethylamino)propyl]-: ACTIVE

Anwendungen

VerwendenN-(3-(Dimethylamino)propyl)dodecanamide is used in the study of surface chemistry and colloids as a new surfactnt for hydrate anti-agglomeration in hydrocarbon flowlines and seabed oil capture.