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Kaliumthiocyanat
KSCN · POTASSIUM ISOTHIOCYANATE · Product Description · POTASSIUM RHODANIDE · Potassium thiocyanide · Rhocya · Arterocyn · Rodanca
Identifikatoren & physikalische Daten
| CAS No. | 333-20-0 |
|---|---|
| Summenformel | CKNS |
| Durchschnittliche Molmasse | 97,18 g/mol |
| Monoisotopische Masse | 96,93885166 g/mol |
| SMILES | N#C[S-].[K+] |
| InChIKey | ZNNZYHKDIALBAK-UHFFFAOYSA-M |
| PubChem CID | 516872 |
| ChEMBL | CHEMBL2106973 |
| ChEBI | CHEBI:30951 |
| EC No. | 206-370-1 |
| DTXSID | DTXSID7029619 |
| Lokaler Name | Kaliumthiocyanat |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 24,8 |
|---|---|
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 4 |
| Formalladung | 0 |
| Komplexität | 34 |
| Dichte | 1.9 g/cm³1.89 @25 °C1.886 |
| Löslichkeit | Solubility in water: very goodH2O: 8 M at 20 °C, clear, colorless2170 g/L (20 ºC) |
| Decomposition | 500 °C |
| Schmelzpunkt | 173 °C173 °C (lit.) |
| Physical Description | Colorless deliquescent solid[Merck Index]COLOURLESS-TO-WHITE HYGROSCOPIC CRYSTALS. |
| Siedepunkt | 500°C |
| Dampfdruck | <0.001 hPa (20 °C) |
| Flammpunkt | 500°C |
| Lagerbedingungen | Store at +5°C to +30°C. |
| Aggregatzustand | Liquid |
| pKa (Säurekonstante) | 0.85(Temp: 25 °C) |
| Wichte | 1.886 |
| Farbe | colorless or white |
| pH | 5.3-8.7 (25℃, 50mg/mL in H2O) |
| Geruch | Odorless |
| Spezifische Wärmekapazität | Cp(crystal): 0.91 J/(g·K), at 25℃ |
| Merck | 14,7691 |
| BRN | 3594799 |
| Stabilität | Stable. Incompatible with nitric acid, strong oxidizing agents, active halogen compounds. |
| Kosmetik-Inhaltsstoffe Funktionen | LIGHT STABILIZER |
| InChI | 1S/CHNS.K/c2-1-3/h3H/q+1/p-1 |
| InChIKey | ZNNZYHKDIALBAK-UHFFFAOYSA-M |
| SMILES | [K]SC#N |
| LogP (Verteilungskoeffizient) | 0.58 |
| CAS Datenbank | 333-20-0(CAS DataBase Reference) |
| NIST chemische Informationen | Potassium thiocyanate(333-20-0) |
| EPA chemische Informationen | Potassium thiocyanate (333-20-0) |
| Absorption | cut-off at 274nm in H2O at 8M |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH302+H312+H332 (45.4%): Harmful if swallowed, in contact with skin or if inhaled [Warning Acute toxicity, oralacute toxicity, dermalacute toxicity, inhalation]H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]H312 (99.6%): Harmful in contact with skin [Warning Acute toxicity, dermal]H318 (29.2%): Causes serious eye damage [Danger Serious eye damage/eye irritation]H319 (28.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H332 (99.6%): Harmful if inhaled [Warning Acute toxicity, inhalation]H400 (13.4%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]H412 (81%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P321, P330, P337+P317, P362+P364, P391, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 284 reports by companies from 24 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| Regulatorische Informationen | Chemical: Thiocyanic acid, potassium saltCommission Regulation (EU) No 188/2011Thiocyanic acid, potassium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Thiocyanic acid, potassium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)05/751/EC, Reg. (EU) No 108/2014Status: Active Update: 24-06-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/5157Potassium thiocyanate: Does not have an individual approval but may be used under an appropriate group standard |
| Weitere Sicherheitsinformationen | IMAP assessments - Thiocyanate salts: Human health tier II assessment |
| Brandgefahren | Not combustible. Gives off irritating or toxic fumes (or gases) in a fire. |
| Gefahrenübersicht | Toxic effects include skin eruptions, psychosis, and collapse[Merck Index] May cause CNS effects (excitement and convulsions)Prolonged or repeated exposure may cause thyroid and CNS effects leading to impaired function and hypothyroidism[ICSC] Human ingestion of 80 mg/kg causes hallucinations, convulsions, and muscle weaknessHuman ingestion of 428 mg/kg causes toxic psychosis, hallucinations, and gastritis[RTECS] Sheep exposed orally during gestation produced goiter in newborn lambsEffects to female fertility observed in rats at high dosesAnother study demonstrated maternal and fetal toxicity with no increase in congenital defects[REPROTOX] Harmful by ingestion, inhalation, and skin absorptionTargets the CNS, cardiovascular system, and thyroid[Sigma-Aldrich MSDS] See Sodium thiocyanate. |
| EG-Einstufung | Symbol: XnR: 20/21/22-32-52/53S: (2)-13-61Note: A |
| Chemical Dangers | Decomposes on heating. This produces very toxic fumes of sulfur compounds, nitrogen oxides and cyanides. Reacts violently with strong oxidants. Contact with water causes a strong cooling effect. |
| Hazard Classes and Categories | Acute Tox. 4 (100%)Acute Tox. 4 (99.6%)Eye Dam. 1 (29.2%)Eye Irrit. 2 (28.2%)Aquatic Acute 1 (13.4%)Aquatic Chronic 3 (81%)Acute toxicity - category 4Eye irritation - category 2AAcute toxicity (Oral) - Category 4Specific target organ toxicity - Repeated exposure - Category 1 (thyroid)Hazardous to the aquatic environment (Acute) - Category 3 |
| Brandbekämpfung | In case of fire in the surroundings, use appropriate extinguishing media. |
| Erste-Hilfe-Maßnahmen | Fresh air, rest.Remove contaminated clothes. Rinse skin with plenty of water or shower.First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention . |
| Sichere Lagerung | Separated from strong oxidants. Dry. Well closed. |
| Verschüttetes entsorgen | Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. |
| Eye Prevention | Wear safety goggles or eye protection in combination with breathing protection. |
| Inhalation Risk | A harmful concentration of airborne particles can be reached quickly when dispersed. |
| Skin Prevention | Protective gloves. |
| Exposure Prevention | PREVENT DISPERSION OF DUST! |
| Ingestion Prevention | Do not eat, drink, or smoke during work. |
| Inhalation Prevention | Use local exhaust or breathing protection. |
| Effects of Long Term Exposure | The substance may have effects on the thyroid and central nervous system. This may result in impaired functions and hypothyroidism. |
| Effects of Short Term Exposure | The substance may cause effects on the central nervous system. This may result in excitement and convulsions. |
| Unerwünschte Wirkungen | Neurotoxin - Other CNS neurotoxin |
| Expositionspfade | The substance can be absorbed into the body by inhalation and by ingestion. |
| Signs and Symptoms | Cough. Further see Ingestion.Confusion. Convulsions. Nausea. Vomiting. Weakness. |
| Wassergefährdungsklasse (WGK) | 1 |
| TSCA-Inventar-Status | TSCA listed |
| Zollcode | 28380000 |
| RTECS-Nr. | XL1925000 |
| R-Sätze (R) | 32-52/53-20/21/22 |
| Toxizität | LD50 orally in mice, rats: 594, 854 mg/kg, Andersen, Chen, J. Am. Pharm. Assoc. 29, 152 (1940) |
| Gefahrensymbole | Xn,Xi |
| hazard_note | Irritant/Hygroscopic |
| Sicherheitshinweise (S) | 13-61-36/37-46 |
| Lagerklasse | 13 - Non Combustible Solids |
| Gefahrenklasse | Acute Tox. 4 DermalAcute Tox. 4 InhalationAcute Tox. 4 OralAquatic Chronic 3Eye Dam. 1 |
Anwendungen & Verwendung
Verwenden
Potassium Thiocyanate has been used as a catalyst in a one-pot reaction of dialkyl acetylenedicarboxylates with indane-1,3-dione. Potassium Thiocyanate has been used as a selective bacterial inhibitor to create ESS-3 broth to allow co-enrichment of the target pathogens and suppress growth of some non-target pathogens
Herstellung & Synthese
synthetische
Potassium thiocyanate may be made by adding caustic potash to a solution of ammonium thiocyanate, followed by evaporation of the solution. NH4SCN + KOH →KSCN + NH4OHAlso, the compound can be prepared by heating potassium cyanide with sulfur:KCN + S →KSCN.