Sodium Phosphate, Monobasic, Monohydrate
PHOSPHATE BUFFER · Sodium dihydrogen phosphate monohydrate · POTASSIUM PHOSPHATE BUFFER · PH 7 BUFFER · Phosphate buffered · SODIUMPHOSPHATEMONOBASIC,MONOHYDRATE,GRANULAR,USP,BP · RIA BUFFER · BUFFER FOR BOD
Identifikatoren & physikalische Daten
| CAS No. | 10049-21-5 |
|---|---|
| Summenformel | H4NaO5P |
| Durchschnittliche Molmasse | 137,99 g/mol |
| Monoisotopische Masse | 137,9694045 g/mol |
| SMILES | O.O=P([O-])(O)O.[Na+] |
| InChIKey | BBMHARZCALWXSL-UHFFFAOYSA-M |
| PubChem CID | 516949 |
| ChEBI | CHEBI:114249 |
| EC No. | 600-102-0 |
| DTXSID | DTXSID6073994 |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 81,6 |
|---|---|
| H-Brücken-Donoren | 3 |
| H-Brücken-Akzeptoren | 5 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 7 |
| Formalladung | 0 |
| Komplexität | 61 |
| Physical Description | Dry PowderWhite odorless solidSlightly deliquescent[Merck Index] White hygroscopic crystals[Sigma-Aldrich MSDS] |
| Schmelzpunkt | 100°C -H₂O |
| Siedepunkt | 399 °C |
| Dichte | 2,04 g/cm3 |
| Lagerbedingungen | Store at +5°C to +30°C. |
| Löslichkeit | H2O: 1 M, clear, colorlessSoluble in waterinsoluble in ethanol, ether and chloroform. |
| Aggregatzustand | Solid |
| pKa (Säurekonstante) | 7.21 |
| Farbe | White semi-transparentor |
| Geruch | Odorless |
| pH | 4.1-4.5 (25℃, 50mg/mL in H2O) |
| Merck | 14,8660 |
| InChI | 1S/Na.H3O4P.H2O/c1-5(2,3)4/h(H3,1,2,3,4)1H2/q+1/p-1 |
| InChIKey | BBMHARZCALWXSL-UHFFFAOYSA-M |
| SMILES | [Na+].[H]O[H].OP(O)([O-])=O |
| LogP (Verteilungskoeffizient) | -2.148 (est) |
| CAS Datenbank | 10049-21-5(CAS DataBase Reference) |
| EPA chemische Informationen | Monosodium phosphate monohydrate (10049-21-5) |
| Absorption | ≤0.01 at 260nm≤0.01 at 280nm |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 76.9% (40 of 52) of all reports.WarningH315 (21.2%): Causes skin irritation [Warning Skin corrosion/irritation]H319 (21.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H335 (21.2%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 52 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Reported as not meeting GHS hazard criteria per 40 of 52 reports by companies.There are 4 notifications provided by 12 of 52 reports by companies with hazard statement code(s).Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| Regulatorische Informationen | Chemical: Phosphoric acid, monosodium salt, monohydratePhosphoric acid, monosodium salt, monohydrate is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Phosphoric acid, monosodium salt, monohydrate are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Monosodium dihydrogen phosphate: Does not have an individual approval but may be used under an appropriate group standard |
| Weitere Sicherheitsinformationen | IMAP assessments - Phosphoric acid, monosodium salt, monohydrate: Human health tier I assessment |
| Gefahrenübersicht | May cause irritation[Sigma-Aldrich MSDS] See Sodium phosphate, monobasic. |
| Hazard Classes and Categories | Skin Irrit. 2 (21.2%)Eye Irrit. 2 (21.2%)STOT SE 3 (21.2%) |
| F | 3 |
| Wassergefährdungsklasse (WGK) | 1 |
| TSCA-Inventar-Status | Yes |
| Zollcode | 2835 22 00 |
| RTECS-Nr. | WA1900000 |
| R-Sätze (R) | 36/37/38-36 |
| Toxizität | LD50 orally in Rabbit: > 2000 mg/kg LD50 dermal Rabbit > 7940 mg/kg |
| Gefahrensymbole | Xi |
| Sicherheitshinweise (S) | 26-36/37/39-36-39-24/25 |
| Lagerklasse | 13 - Non Combustible Solids |
Anwendungen & Verwendung
Beschreibung
Sodium Phosphate Monobasic Monohydrate is a reagent with very high buffering capacity widely used in molecular biology, biochemistry and chromatography. it can be used as a buffer to adjust pH. In medicine, it is sometimes used as a stimulant laxative before certain operations and medical procedures. Sodium Phosphate Monobasic Monohydrate is often used in foods and in water treatment. It is used as sequestrant, emulsifier, mordant in dyeing, reagent and buffer in foods and analytical chemistry. It is applied as a fireproofing agent and for weighting silk in tanning. It is employed in manufacturing of enamels, ceramics, detergents, boiler compounds, in soldering and brazing instead of borax. Monobasic sodium phosphate is used in baking powders, acid cleansers, electroplating, as a dry acidulant, and in treating boiler water.
Verwenden
Sodium Phosphate Monobasic Monohydrate is often used in foods and in water treatment. it can be used as a buffer to adjust pH. In medicine, it is sometimes used as a stimulant laxative before certain operations and medical procedures.
Herstellung & Synthese
synthetische
Monobasic sodium phosphate can be prepared by partial neutralization of phosphoric acid with sodium hydroxide in equimolar amounts: H3PO4+ NaOH →NaH2PO4+ H2O It also can be made by treating disodium hydrogen phosphate with phosphoric acid in proper stoichiometric amount: Na2HPO4+ H3PO4→2NaH2PO4