Dichlorisocyanursäure, Kalium-Salz

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

If material on fire or involved in fire: Flood with water. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. /Dichloroisocyanuric acid, dry or salts/

If fire becomes uncontrollable - consider evacuation of one-half (1/2) mile radius. /Dichloroisocyanuric acid, dry or salts/

Approach fire from upwind to avoid hazardous vapors and toxic decomposition products. Fight fire from protected location or maximum possible distance. Use remote equipment whenever possible. Use flooding quantities of water or fire-involved containers. If necessary use water spray to keep fire-exposed containers cool.

Store in a cool, dry, well-ventilated location. Outside or detached storage is preferred. Must be stored in a dry location on pallets arranged according to NFPA 43A, Code for Storage of Liquid and Solid Oxidizers. Separate from combustible, oxidizing materials, ammonia, sodium carbonate (soda ash), calcium hypochlorite, hydrogen peroxide.

Keep water away from release. Approach release from upwind. Isolate leaking containers, if this can be done without undue risk. Prompt cleanup and removal are necessary. Do not create dust. Shovel into suitable dry container. Control run-off and isolate discharge material for proper disposal.

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. /Dichloroisocyanuric acid, dry or salts/

Personnel protection: .. Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water. ... If contact with the material is anticipated, wear appropriate chemical protective clothing. Approach fire with caution. /Dichloroisocyanuric acid, dry or salts/

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

Dust mask or chlorine canister mask; goggles; rubber gloves and other protective clothing to prevent contact with skin. (USCG, 1999)

/SRP: NIOSH certified respirator/ or chlorine canister mask; goggles; rubbber gloves or other protective clothing to prevent contact with skin.

Dichloroisocyanurate, potassium salt (CAS# 2244-21-5) was evaluated for acute oral toxicity. The test substance was administered orally to Sprague-Dawley albino rats. Dosage levels and mortality data are as follows: 1000 (0/2 M, 1/3 F); 1260 (0/3 M, 2/2 F); 1580 (1/2 M, 3/3 F); and 2000 mg/kg of body weight (3/3 M, 2/2 F), with most deaths occurring within 2 days. Clinical signs included reduced appetite and activity, increasing weakness, collapse, and death. Necropsy findings revealed hemorrhagic areas of the lungs, liver discoloration, and acute gastrointestinal inflammation. The LD50 was determined to be 1400 mg/kg b.w.

Dichloroisocyanurate, potassium salt (CAS# 2244-21-5) was evaluated for acute dermal toxicity. The test substance was applied to the skin of New Zealand albino rabbits for 24-hours. Dosage levels and mortality data are as follows: 1260 (0/1 M); 2000 (0/1 F); 3160 (1/1 M in 4-days); and 5010 mg/kg b.w. (1/1 F in 3-days). Clinical signs included reduced appetite and activity, increasing weakness, collapse, and death. Necropsy findings revealed hemorrhagic areas of the lungs and liver, enlarged gall bladder, and gastrointestinal inflammation. The LD50 was determined to be greater than 2,000 mg/kg b.w.

Dichloroisocyanurate, potassium salt (CAS# 2244-21-5) was evaluated for eye irritation. The test substance was applied to the eyes of New Zealand white rabbits at a dose level of 100.0 mg of finely ground powder for 24-hours. Clinical signs included immediate discomfort, slight to moderate erythema which progressed to severe erythema within 24-hours, very slight edema, and a copious discharge which later contained a whitish exudate. At 48-hours there was gradual improvement. The test substance was determined to be a slight eye irritant.

Dichloroisocyanurate, potassium salt (CAS# 2244-21-5) was evaluated for primary dermal irritation. The test substance was applied as a finely ground powder moistened with water to the skin of New Zealand albino rabbits at a dose level of 0.5 g for 24-hours. Clinical signs included very slight erythema and edema which progressed to corrosion within 24-hours. From 14-17 days, there was slight loosening about edges of scab showing injury in depth. The test substance was determined to be corrosive.

The toxicity is apparently due to corrosive action on stomach lining rather than to any systemic effects. In the presence of moisture, as in the eyes, upper respiratory tract or on moist or abraded skin, it is moderately irritating. In some individuals bronchospasm may result from breathing the dust. /Trichloroisocyanuric acid/

NO IRRITATION ON THE INTACT SKIN OF RABBITS WAS OBSERVED AFTER APPLICATION OF SODIUM (POTASSIUM) DICHLOROISOCYANURATE IN THE FORM OF DRY POWDER FOR 24 HR.

NO SIGNIFICANT IRRITATION WAS REPORTED WHEN ONE EYE OF A RABBIT WAS EXPOSED TO SOLN OF POTASSIUM DICHLOROISOCYANURATE (3 PPM AS AVAILABLE CHLORINE) FLOWING AT APPROX 330 ML/HR, 1 HR/DAY, 5 DAYS/WK, FOR TOTAL OF 30 EXPOSURES.

Occupational exposure to potassium dichloroisocyanurate may occur through dermal contact or inhalation where this compound us produced or used. The general population will be exposed to potassium dichloroisocyanurate through dermal contact with this compound where it is used as a sanitizer in water treatment and household cleaning products. (SRC)