Grundinformationen
- Standard-SMILES
O.O=[Si]=O.[O]=[Al][O][Al]=[O]- InChIKey
SVPXDRXYRYOSEX-UHFFFAOYSA-N- Summenformel
- Al2H2O6Si
- Durchschnittliche Molmasse
- 180,06 g/mol
Überblick
Bentoquatam is a topical medication intended to act as a shield against exposure to the irritating substance urushiol, found in plants such as poison ivy or poison oak. Bentoquatam contains bentonite, a clay, and is only effective as long as the film is visible on the skin.
Namen und Bezeichner
- Bevorzugter Name
- Quaternium 18-bentonite
- IUPAC
- dioxosilane;oxo(oxoalumanyloxy)alumane;hydrate
- Lokaler Name
- Bentonit
- Englischer Name
- Bentonite
- Summenformel
- Al2O3.4(SiO2).H2O
- Molmasse
- 360.31
Namen und Synonyme
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Datenbank-Bezeichner
- CAS
1302-78-9、1340-69-8- PubChem CID
- 517273
- ChEMBL
CHEMBL1201446- EC Number
- 932-858-5
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 78,5 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 6
- Frei drehbare Bindungen
- 0
- Schwere Atome
- 9
- Formalladung
- 0
- Komplexität
- 52,4
Experimentelle und physikochemische Eigenschaften
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
Physikochemische Eigenschaften
- Dichte
- 2 · 2~3g/cm3
- storage temp.
- Store at room temperature, keep dry and cool
- Löslichkeit
- Practically insoluble in water and in aqueous solutions. It swells with a little water forming a malleable mass.
- Aggregatzustand
- powder
- Farbe
- Light yellow or green, cream,pink, gray to black solid
- Geruch (Odor)
- odorless, sl. earthy taste
- Wasserlöslichkeit
- Insoluble in water and forms a colloidal solution.
- Merck
- 14 · 14,1055
- Dielectric constant
- 8.1 · 8.1(Ambient)
- Stabilität
- Stable.
- Kosmetik-Inhaltsstoffe Funktionen
- EMULSION STABILISINGBULKINGABSORBENTCOLORANTVISCOSITY CONTROLLING
- InChIKey
- KARVSHNNUWMXFO-UHFFFAOYSA-N
- SMILES
- [Si](=O)=O.[Si](=O)=O.[Si](=O)=O.[Si](=O)=O.[Al]21O[Al](O2)O1.O
- CAS Datenbank
- 1302 · 1302-78-9
- EPA chemische Informationen
- Bentonite (1302-78-9)
Sicherheit und Regulatorisches
GHS-Klassifizierung
GHS Classification
This chemical does not meet GHS hazard criteria for 100% (36 of 36) of all reports.
Not Classified
Aggregated GHS information provided per 36 reports by companies from 1 notifications to the ECHA C&L Inventory.
Gefahrenhinweise
Regulatory Information
Chemical: Quaternium 18-bentonite
Tixogel VP: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Sicherheitsdaten
- wgk
- 3
- tsca
- TSCA listed
- RTECS-Nr.
- CT9450000
- risk_code
- 20/22-8
- Toxizität
- LD50 intravenous in rat: 35mg/kg
- safety_code
- 22-24/25
- Speicherklasse
- 11 - Combustible Solids
- Giftige Stoffe Daten
- 1302-78-9(Hazardous Substances Data)
Chemie und Industrie
Pharmakologische Informationen
Pharmacodynamics
Bentoquatam protects the skin like a shield against poison ivy, poison oak, and poison sumac by physically blocking skin contact with their resin. The best protection against getting these conditions is to avoid contact with these plants. This medicine does not dry oozing and weeping caused by the rash of poison ivy, poison oak, or poison sumac.
Mechanism of Action
The mechanism of action is unknown. It is thought topically applied bentoquatam acts as a physical barrier that interferes with the adsorption of antigens onto the skin and reduces absorption of antigens into the skin. It probably does not work by modifying the systemic allergic response.
Anwendungen
Verwendenbentonite (bentonite clay) is used to regulate the viscosity and suspension properties of a cosmetic formulation. It also acts as an overall formula stabilizer. Bentonite’s water-absorption capabilities allow it to form a gelatinous mass. Considered a noncomedogenic raw material, bentonite is a colloidal aluminum silicate clay.
Vor- und nachgelagerte Produkte
Vorgelagerte Rohstoffe
Nachgelagerte Produkte
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Ergänzende Hinweise
DefinitionA type of clay that is used as an adsorbent in making paper. The gelatinous suspension it forms with water is used to bind together the sand for making iron castings. Chemically bentonite is an aluminosilicate of variable composition.
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