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Proxymetacainhydrochlorid
PROPARACAINE HCL · alcaine · ophthain · ophthetic · keracaine · chibro-heracaine · Proparacaine HCI · Proparacaine HydrochL
Identifikatoren & physikalische Daten
| CAS No. | 5875-06-9 |
|---|---|
| Summenformel | C16H27ClN2O3 |
| Durchschnittliche Molmasse | 330,856 g/mol |
| Monoisotopische Masse | 330,1710204 g/mol |
| SMILES | CCCOc1ccc(C(=O)OCCN(CC)CC)cc1N.Cl |
| InChIKey | BFUUJUGQJUTPAF-UHFFFAOYSA-N |
| PubChem CID | 517321 |
| ChEMBL | CHEMBL1200464 |
| EC No. | 227-541-7 |
| DTXSID | DTXSID0049022 |
| Lokaler Name | Proxymetacainhydrochlorid |
Chemische & physikalische Eigenschaften
| Schmelzpunkt | 182.0-183.3° |
|---|---|
| Lagerbedingungen | Inert atmosphere,Store in freezer, under -20°C |
| Löslichkeit | Chloroform (Slightly), Methanol, Water |
| Aggregatzustand | Solid |
| pKa (Säurekonstante) | 3.2(at 25℃) |
| Farbe | White to Off-White |
| Merck | 14,7807 |
| Hauptanwendungen | pharmaceutical (small molecule) |
| InChI | InChI=1S/C16H26N2O3.ClH/c1-4-10-20-15-8-7-13(12-14(15)17)16(19)21-11-9-18(5-2)6-3/h7-8,12H,4-6,9-11,17H2,1-3H31H |
| InChIKey | BFUUJUGQJUTPAF-UHFFFAOYSA-N |
| SMILES | C(OCCN(CC)CC)(=O)C1=CC=C(OCCC)C(N)=C1.[H]Cl |
| CAS Datenbank | 5875-06-9(CAS DataBase Reference) |
Sicherheit & Vorschriften
| Wassergefährdungsklasse (WGK) | 3 |
|---|---|
| Zollcode | 2922504500 |
| RTECS-Nr. | DG3065000 |
| R-Sätze (R) | 20/21/22-36-43 |
| Gefahrensymbole | Xn |
| Sicherheitshinweise (S) | 26-36 |
| Lagerklasse | 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects |
Anwendungen & Verwendung
Beschreibung
Proparacaine Hydrochloride is the hydrochloride salt form of proparacaine, a benzoic acid derivative with local anesthetic property. Proparacaine hydrochloride stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting sodium ion influx required for the initiation and conduction of impulses within the neuronal cell, and resulting in a loss of sensation.
Verwenden
Topical anesthetic (ophthalmic); Neuronal conductance inhibitor.