Semicarbazid

Semicarbazide

HCID 5196CAS 57-56-7
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Grundinformationen

Standard-SMILES
NNC(N)=O
InChIKey
DUIOPKIIICUYRZ-UHFFFAOYSA-N
Summenformel
CH5N3O
Durchschnittliche Molmasse
75,07 g/mol
Monoisotopische Masse
75,04326178

Überblick

Semicarbazide is a monocarboxylic acid amide that is urea where one of the amino groups has been replaced with hydrazine. It is a monocarboxylic acid amide, a carbohydrazide, a member of ureas and a one-carbon compound.

Namen und Bezeichner

Bevorzugter Name
Semicarbazide
IUPAC
aminourea
Lokaler Name
Semicarbazid
Englischer Name
Semicarbazide
Summenformel
CH5N3O
Molmasse
75.07

Namen und Synonyme

SemicarbazideHYDRAZINECARBOXAMIDEAminourea57-56-7CarbamylhydrazineCarbazamideSemikarbazidAminomocovinaCarbamoylhydrazineCarbamic acid, hydrazide37QUC23K2XDTXSID7043823
Weitere Namen anzeigen
C02077amino-ureCarbazinamide
CHEBI:28306RefChem:182342DTXCID5023823200-339-6Urea, amino-AminoharnstoffHydrazine, carbamoyl-Carbamidsaeurehydrazid

Datenbank-Bezeichner

CAS
57-56-7
PubChem CID
5196
DTXSID
DTXSID7043823
ChEMBL
CHEMBL903
ChEBI
CHEBI:28306
UNII
37QUC23K2X
EC Number
200-339-6
Nikkaji
J4.582I

Eigenschaften

Berechnete Struktureigenschaften

XLogP
-1,8
Polarare Oberfläche (TPSA)
81,1 Ų
H-Brücken-Donoren
3
H-Brücken-Akzeptoren
2
Frei drehbare Bindungen
0
Schwere Atome
5

Experimentelle und physikochemische Eigenschaften

Chemical ClassesNitrogen Compounds -> Hydrazides
Endocrine DisruptorsPotential endocrine disrupting compound
Food Contact SubstancesFCS -> FDA Cumulative Estimated Daily Intake (CEDI)

Physikochemische Eigenschaften

Schmelzpunkt
96 °C · 96°C
Siedepunkt
133.71 °C · 133.71°C (rough estimate)
Dichte
1.286 · 1.286±0.06 g/cm3(Predicted)
Brechungsindex
1.4451 · 1.4451 (estimate)
storage temp.
2 · 2-8°C, protect from light
Aggregatzustand
powder

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 4 Einträge

Danger

H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 76 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Regulatory InformationRegulation (EC) No 178/2002 (amended)
Hazards Summary · 1 Eintrag

Developmental toxicity and teratogenicity observed in rats from single 17 mg/kg doses; Teratogenicity also observed in chickens; [REPROTOX] Causes convulsion in oral, intraperitoneal, and intravenous lethal-dose studies of mice; [RTECS] See Semicarbazide hydrochloride.

Hazard Classes and CategoriesAcute Tox. 3 (100%)

Sicherheitsdaten

wgk
3
tsca
TSCA listed
risk_code
22
hazard_code
Xn
safety_code
22
Speicherklasse
13 - Non Combustible Solids

Chemie und Industrie

Pharmakologische Informationen

MeSH Pharmacological ClassificationSubstances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.

Verwendung und Herstellung

Uses · 1 Eintrag

Produced in trace amounts from heat processing of jar-seals containing azodicarbonamide; [REPROTOX] Found in foods from the thermal breakdown of azodicarbonamide in sealing gaskets used on metal lids of jars and bottles; Also a metabolite of the veterinary medication nitrofurazone (banned in the EU); [ExPub: The EFSA Journal (2005) 219, 1-36]

General Manufacturing InformationHydrazinecarboxamide: ACTIVE
Anwendungen · 2 Einträge

BeschreibungSemicarbazide (SM) is a metabolite of the nitrofurane Nitrofurazone (5-nitro-2- furaldehyde-semicarbazone), used as indicator to detect the use of nitrofurazone in food-producing animals due to their carcinogenic properties the use of nitrofurans is prohibited within the EU in animal breeding (Commission Regulation 37/2010) . to harmonise the detection of semicarbazide a Minimum Required Performance Limit (MRPL) of 1 µg/kg is set within the EU (Commission Decision 2003/181).

VerwendenSemicarbazide is used as a potent nucleophile; forms many crystalline carbonyl derivatives.

Vor- und nachgelagerte Produkte

Anbieter50 Anbieter

郑州阿尔法化工有限公司+86-18530059196 · [email protected]
Hebei Chuanghai Biotechnology Co., Ltd+86-17732866630 · [email protected]
Hebei Zhuanglai Chemical Trading Co Ltd+86-16264648883 · [email protected]
上海康朗生物科技有限公司021-61998208 18217752821 · [email protected]
成都超九八生物科技有限公司13348960310 13348960310 · [email protected]

Ergänzende Hinweise

DefinitionChEBI: A monocarboxylic acid amide that is urea where one of the amino groups has been replaced with hydrazine.

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