HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Prednicarbat
Regemt · Regenit · HOE-777 · Dermatop · Prednitop · S-77-0777 · PREDNICARBATE · UNII-V901LV1K7D

Identifikatoren & physikalische Daten
| CAS No. | 73771-04-7 |
|---|---|
| Summenformel | C27H36O8 |
| Durchschnittliche Molmasse | 488,577 g/mol |
| Monoisotopische Masse | 488,24101811 g/mol |
| SMILES | CCOC(=O)OC1(C(=O)COC(=O)CC)CCC2C3CCC4=CC(=O)C=CC4(C)C3C(O)CC21C |
| InChIKey | FNPXMHRZILFCKX-UHFFFAOYSA-N |
| PubChem CID | 52421 |
| DTXSID | DTXSID40860963 |
| Lokaler Name | Prednicarbat |
Chemische & physikalische Eigenschaften
| Schmelzpunkt | 110-112°mp 183° |
|---|---|
| Siedepunkt | 640.7±55.0 °C(Predicted) |
| Dichte | 1.25±0.1 g/cm3(Predicted) |
| Lagerbedingungen | Refrigerator |
| Löslichkeit | Practically insoluble in water, freely soluble in acetone and in ethanol (96 per cent), sparingly soluble in propylene glycol. It shows polymorphism (5.9). |
| pKa (Säurekonstante) | 14.05±0.70(Predicted) |
| Aggregatzustand | Solid |
| Farbe | White to Off-White |
| InChIKey | FNPXMHRZILFCKX-IVRISGIPNA-N |
| SMILES | [C@@]1(OC(=O)OCC)(C(=O)COC(=O)CC)CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)[C@@]3([H])[C@@H](O)C[C@]12C |&1:0,17,19,29,31,33,36,r| |
Sicherheit & Vorschriften
| Zollcode | 2937290000 |
|---|
Anwendungen & Verwendung
Beschreibung
Prednicarbate is a potent topical antiinflammatory agent with minimal systemic effects. It is useful in the treatment of cutaneous inflammatory disorders such as eczema and psoriasis.
Verwenden
Topical anti-inflammatory agent. Glucocorticoid. Prednicarbate (Dermatop E) is a synthetic nonfluorinated topical corticosteroid.