6-Hydroxyindole

HCID 524508CAS 2380-86-1
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Grundinformationen

Standard-SMILES
Oc1ccc2cc[nH]c2c1
InChIKey
XAWPKHNOFIWWNZ-UHFFFAOYSA-N
Summenformel
C8H7NO
Durchschnittliche Molmasse
133,15 g/mol
Monoisotopische Masse
133,05276384

Überblick

structure in first source

Namen und Bezeichner

Bevorzugter Name
6-Hydroxyindole
IUPAC
1H-indol-6-ol
Englischer Name
6-Hydroxyindole
Summenformel
C8H7NO
Molmasse
133.15

Namen und Synonyme

6-Hydroxyindole2380-86-11H-indol-6-olIMEXINE OBA3I03JZ599TDTXSID20178497RefChem:104788DTXCID50100988417-020-46-indololMFCD00152101indol-6-ol
Weitere Namen anzeigen
6(1H)-indolol6-Hydroyindole6-HydroxyindoL6-carboxylindoline6-Hydroxyindole,97%6-Hydroxy-1H-indole
CHEMBL24138226-hydroxy indoleIndol-6-ol (6CI,7CI,8CI)indolol6hydroxyindoleUNII-3I03JZ599T6-hydroxy-indole1H-indole-6-ol

Datenbank-Bezeichner

CAS
2380-86-1
PubChem CID
524508
DTXSID
DTXSID20178497
ChEMBL
CHEMBL2413822
UNII
3I03JZ599T
EC Number
417-020-4、626-440-9
Nikkaji
J467.722F

Eigenschaften

Berechnete Struktureigenschaften

XLogP
2,3
Polarare Oberfläche (TPSA)
36 Ų
H-Brücken-Donoren
2
H-Brücken-Akzeptoren
1
Frei drehbare Bindungen
0
Schwere Atome
10

Experimentelle und physikochemische Eigenschaften

Cosmetics · 2 Einträge

Cosmetic ingredients (6-Hydroxyindole) -> CIR (Cosmetic Ingredient Review)

Hair dyeing

Physikochemische Eigenschaften

Schmelzpunkt
125 · 125-128 °C
Siedepunkt
343.2 · 343.2±15.0 °C(Predicted)
Dichte
1.327 · 1.327±0.06 g/cm3(Predicted)
storage temp.
2 · Sealed in dry,2-8°C
Löslichkeit
Chloroform (Slightly, Heated), Methanol (Slightly)
pka
10.07 · 10.07±0.40(Predicted)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

Danger

H302: Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P272, P273, P280, P301+P317, P302+P352, P305+P354+P338, P317, P321, P330, P333+P317, P362+P364, P391, and P501 (click each P-code to see the statement)

Danger

H302 (95.3%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P272, P273, P280, P301+P317, P302+P352, P305+P354+P338, P317, P321, P330, P333+P317, P362+P364, P391, and P501 (click each P-code to see the statement)

Gefahrenhinweise

Regulatory InformationStatus: Active Update: 19-04-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/33474
Hazard Classes and Categories · 4 Einträge

Acute Tox. 4 (100%)

Acute Tox. 4 (95.3%)

Acute toxicity - category 4

Acute Tox. 4 *

Toxikologische Informationen

Toxicity SummarySafe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org

Sicherheitsdaten

wgk
3
ridadr
UN 3077
hs_code
29339900
risk_code
36/37/38-51/53-43-41-22
hazard_code
Xi,N,Xn
hazard_note
Irritant

Chemie und Industrie

Pharmakologische Informationen

Metabolism/Metabolites6-Hydroxyindole is a known human metabolite of indole.

Verwendung und Herstellung

UsesCIR ingredient: 6-Hydroxyindole
Household ProductsInformation on 14 consumer products that contain 6-hydroxyindole in the following categories is provided:
Use ClassificationCosmetics -> Hair dyeing
Anwendungen · 1 Eintrag

VerwendenReactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulatorsReactant for asymmetrical synthesis of notoamide J as a potential biosynthetic precursor of prenylated indole alkaloidsReactant for preparation of (quinolinyloxymethyl)isoxazolecarboxylate esters antituberculosis agentsReactant for preparation of indolyl(propanolamine) derivatives as HIV inhibitorsReactant for preparation of indoleoxyacetic acid derivatives as peroxisome proliferator-activated receptor agonistsReactant for preparation of 1-aroylindole 3-aroylindoles combretastatin A-4 analogs as antitumor agents and tubulin polymerization inhibitors

Vor- und nachgelagerte Produkte

Nachgelagerte Produkte

Anbieter50 Anbieter

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
INTATRADE GmbH+49 3493/605464 · [email protected]
爱斯特（成都）生物制药股份有限公司+86-28-85122536 85324413 · [email protected]
韶远科技（上海）有限公司021-50795510 4000665055 · [email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]

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