HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Vitamin D
Vitamin D (8CI, 9CI, ACI) · TIANFU-CHEM CAS NO.1406-16-2 Vitamin D
Identifikatoren & physikalische Daten
| CAS No. | 1406-16-2 |
|---|---|
| Summenformel | C27H44O |
| Durchschnittliche Molmasse | 384,6 g/mol |
| Monoisotopische Masse | 384,33921603 g/mol |
| SMILES | C=C1CC[C@H](O)C/C1=C/C=C1\CCC[C@]2(C)[C@@H]([C@H](C)CCCC(C)C)CC[C@@H]12 |
| InChIKey | QYSXJUFSXHHAJI-YRZJJWOYSA-N |
| PubChem CID | 5280795 |
| ChEMBL | CHEMBL1042 |
| ChEBI | CHEBI:28940 |
| EC No. | 200-673-2 |
| DTXSID | DTXSID6026294 |
| Lokaler Name | Vitamin D |
Chemische & physikalische Eigenschaften
| XLogP | 7,9 |
|---|---|
| Polarare Oberfläche (TPSA) | 20,2 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 1 |
| Frei drehbare Bindungen | 6 |
| Schwere Atome | 28 |
| Formalladung | 0 |
| Komplexität | 610 |
| Stoffklassen | Biological Agents -> Vitamins and Derivatives |
| Arzneimittel | Pharmaceuticals -> Listed in ZINC15 |
| Lipide | Lipids -> Sterol Lipids [ST] -> Secosteroids [ST03] -> Vitamin D3 and derivatives [ST0302] |
| SpringerMaterials Properties | Angular frequency |
| Pestizide | RodenticidesActive substance -> EU Pesticides database: Not approved |
| LogP (Verteilungskoeffizient) | 10.24 |
| Geruch | ODORLESS |
| Lebensmittelzusatzstoffe | NUTRIENT SUPPLEMENT -> FDA Substance added to food |
| Color/Form | Fine needles from dilute acetoneWHITE CRYSTALSColorless crystals |
| Löslichkeit | Insoluble (NTP, 1992)Sol in the usual org solventsslightly sol in vegetable oils |
| Human Drugs | FDA approved drugs -> Active ingredientVitamins and minerals |
| Endocrine Disruptors | Potential endocrine disrupting compound |
| Kosmetik-Inhaltsstoffe Funktionen | SKIN CONDITIONING |
| LogP (Verteilungskoeffizient) | 9.085 (est) |
| EPA chemische Informationen | Vitamin D (1406-16-2) |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH300: Fatal if swallowed [Danger Acute toxicity, oral]P260, P262, P264, P270, P271, P280, P284, P301+P316, P302+P352, P304+P340, P316, P319, P320, P321, P330, P361+P364, P403+P233, P405, and P501 (click each P-code to see the statement)H300 (14.3%): Fatal if swallowed [Danger Acute toxicity, oral] |
|---|---|
| Regulatorische Informationen | Chemical: 9,10-Secocholesta-5,7,10(19)-trien-3-ol, (3.beta.,5Z,7E)-Regulation (EC) No 178/2002 (amended)2004/129/ECCholecalciferol: HSNO Approval: HSR002778 Approved with controls |
| Weitere Sicherheitsinformationen | IMAP assessments - Calciferols: Human health tier II assessment |
| DOT-Kennzeichnung | Poison |
| Brandgefahren | Flash point data for this chemical are not available. It is probably combustible. (NTP, 1992) |
| Gesundheitsgefahren | SYMPTOMS: Symptoms of exposure to this compound may include weakness, fatigue, lassitude headache, nausea, vomiting, diarrhea, polyuria, polydipsia, nocturia, decrease urinary concentrating ability, proteinuria, tissue calcification, hypertension and osteoporosis. (NTP, 1992) |
| Gefahrenübersicht | May cause irritationHighly toxic by ingestion and skin absorptionToxic by inhalationProlonged or repeated ingestion exposure may cause organ injuryTargets the kidney and heartMay cause reproductive toxicity and teratogenicity[Sigma-Aldrich MSDS] See Vitamin D. |
| FDA-Anforderungen | The Approved Drug Products with Therapeutic Equivalence Evaluations List identifies currently marketed prescription drug products, incl cholecalciferol, approved on the basis of safety and effectiveness by FDA under sections 505 of the Federal Food, Drug, and Cosmetic Act.Cholecalciferol is a food additive permitted for direct addition to food for human consumption, as long as 1) the quantity of the substance added to food does not exceed the amount reasonably required to accomplish its intended physical, nutritive, or other technical effect in food, and 2) any substance intended for use in or on food is of appropriate food grade and is prepared and handled as a food ingredient. |
Anwendungen & Verwendung
Verwenden
vitamin D acts as a keratinization regulator, helping to improve skin feel and firmness with repeated use. This vitamin is absorbed through the skin’s outer layers. Studies are indicating that vitamin D is an important factor in epidermal cell turnover. It is generally found in combination with vitamin A, as such a mixture appears to help epithelial growth and promote good skin pigmentation. Like vitamin A, vitamin D is a major constituent of many fish and vegetable oils.