HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
6-Keto-PGE1
6-Keto-PGE1 · 6-oxo-prostaglandin E1 · 6-KETO PROSTAGLANDIN E1 · ROUDCKODIMKLNO-CTBSXBMHSA-N · 6-keto Prostaglandin E1 MaxSpecStandard · 6-keto Prostaglandin E1 Lipid Maps MS Standard · 6,9-dioxo-11α,15S-dihydroxy-prost-13E-en-1-oic acid · 6,9-Dioxo-11alpha,15s-dihydroxy-prost-13e-en-1-oic acid
Identifikatoren & physikalische Daten
| CAS No. | 67786-53-2 |
|---|---|
| Summenformel | C20H32O6 |
| Durchschnittliche Molmasse | 368,5 g/mol |
| Monoisotopische Masse | 368,21988874 g/mol |
| SMILES | CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CC(=O)CCCCC(=O)O |
| InChIKey | ROUDCKODIMKLNO-CTBSXBMHSA-N |
| PubChem CID | 5280889 |
| ChEMBL | CHEMBL138482 |
| ChEBI | CHEBI:28269 |
| EC No. | 688-563-4 |
| DTXSID | DTXSID701318279 |
Chemische & physikalische Eigenschaften
| XLogP | 1,2 |
|---|---|
| Polarare Oberfläche (TPSA) | 112 |
| H-Brücken-Donoren | 3 |
| H-Brücken-Akzeptoren | 6 |
| Frei drehbare Bindungen | 13 |
| Schwere Atome | 26 |
| Formalladung | 0 |
| Komplexität | 499 |
| Lipide | Fatty Acyls [FA] -> Eicosanoids [FA03] -> Prostaglandins [FA0301] |
| Physical Description | Solid |
| Lagerbedingungen | −20°C |
| Löslichkeit | Ethanol: >50 mg/ml (from PGE1)DMF: >100 mg/ml (from PGE1)DMSO: >50 mg/ml (from PGE1)PBS pH 7.2: >1.6 mg/ml (from PGE1) |
| Aggregatzustand | Liquid |
| Farbe | Colorless to light yellow |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 38 reports by companies from 1 notifications to the ECHA C&L Inventory. |
|---|---|
| Hazard Classes and Categories | Acute Tox. 3 (100%) |
| R-Sätze (R) | 25 |
| Gefahrensymbole | T |
| Sicherheitshinweise (S) | 45 |
Anwendungen & Verwendung
Verwenden
6-Keto-PGE1 is a metabolite of prostacyclin(P839060). Prostacyclin is an Eicosanoid which prevents the formation of platelet plugs and is an effective vasodilator.