Grundinformationen
- Standard-SMILES
CCN(CC)Cc1nccn1-c1ccc([N+](=O)[O-])cc1C(=O)c1ccccc1Cl.O=C(O)/C=C/C(=O)O- InChIKey
JDQAUUIBFFFOOV-WLHGVMLRSA-N- Summenformel
- C25H25ClN4O7
- Durchschnittliche Molmasse
- 528,9 g/mol
- Monoisotopische Masse
- 528,14117682
Überblick
Nizofenone fumarate is a member of benzophenones.
Namen und Bezeichner
- Bevorzugter Name
- Methanone, (2-chlorophenyl)(2-(2-((diethylamino)methyl)-1H-imidazol-1-yl)-5-nitrophenyl)-, (2E)-2-butenedioate (1:1)
- IUPAC
- (E)-but-2-enedioic acid;(2-chlorophenyl)-[2-[2-(diethylaminomethyl)imidazol-1-yl]-5-nitrophenyl]methanone
- Englischer Name
- Nizofenone
- Summenformel
- C25H25ClN4O7
- Molmasse
- 528.9416
Namen und Synonyme
Weitere Namen anzeigen
Datenbank-Bezeichner
- CAS
54533-86-7、93929-95-4- PubChem CID
- 5282422
- DTXSID
DTXSID5048637- ChEBI
CHEBI:31914- UNII
- 1I1Z517Z3Y
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 159 Ų
- H-Brücken-Donoren
- 2
- H-Brücken-Akzeptoren
- 9
- Frei drehbare Bindungen
- 9
- Schwere Atome
- 37
- Formalladung
- 0
- Komplexität
- 688
Physikochemische Eigenschaften
- Schmelzpunkt
- 157 · 157-158℃
- storage temp.
- 2 · 2-8°C
Sicherheit und Regulatorisches
Sicherheitsdaten
- Toxizität
- LD50 in male, female mice, male, female rats (mg/kg): 495, 504, 1711, 1580 orally; 62, 70, 63, 65 i.v.; 270, 278, 1830, 1629 s.c. (Horizoe)
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.
Zugehörige Reaktionen
Keine Reaktionsaufzeichnungen unter den aktuellen Filterkriterien.
Verknüpfte Notizen
Wird geladen…