HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HCID 5283113Erstellt: 4. November 2026
9-Oxo-15S-hydroxy-5Z,8(12),13E,17Z-prostatetraenoic acid
PGB3 · PROSTAGLANDIN B3 · DQRGQQAJYRBDRP-UNBCGXALSA-N · 9-Oxo-15s-hydroxy-prosta-5z,8(12),13e,17z-tetraen-1-oic acid · (5Z,13E,15S,17Z)-15-Hydroxy-9-oxoprosta-5,8(12),13,17-tetraen-1-oic acid · 7-[2-[(3S)-3-hydroxyocta-1,5-dienyl]-5-oxocyclopenten-1-yl]hept-5-enoic acid · Prosta-5,8(12),13,17-tetraen-1-oic acid, 15-hydroxy-9-oxo-, (5Z,13E,15S,17Z)-
https://huagongshe.com/de/chemical/5283113
Identifikatoren & physikalische Daten
| CAS No. | 36614-32-1 |
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| Summenformel | C20H28O4 |
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| Durchschnittliche Molmasse | 332,44 g/mol |
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| Monoisotopische Masse | 332,19875938 g/mol |
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| SMILES | CC/C=C\C[C@H](O)/C=C/C1=C(C/C=C\CCCC(=O)O)C(=O)CC1 |
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| InChIKey | DQRGQQAJYRBDRP-UNBCGXALSA-N |
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| PubChem CID | 5283113 |
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| ChEBI | CHEBI:134511 |
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| DTXSID | DTXSID901372554 |
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Chemische & physikalische Eigenschaften
| Siedepunkt | 548.8±50.0 °C(Predicted) |
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| Dichte | 1.135±0.06 g/cm3(Predicted) |
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| Löslichkeit | DMF: >75 mg/ml (from PGB2)DMSO: >50 mg/ml (from PGB2)Ethanol: >100 mg/ml (from PGB2)PBS pH 7.2: >2 mg/ml (from PGB2) |
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| pKa (Säurekonstante) | 4.74±0.10(Predicted) |
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Sicherheit & Vorschriften
| Alarmwort | Achtung |
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| Gefahrenhinweise | Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code H225 |
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Anwendungen & Verwendung
Beschreibung
Prostaglandin B3 (PGB3) is a non-enzymatic dehydration product resulting from the treatment of Prostaglandin E3 (PGE3) with strong base. In a structure-activity binding study to determine the affinity of various prostaglandins to human PPARγ, PGB3 exhibited a Ki value greater than 1 mM. In contrast, PGB1 and PGB2 showed significantly higher affinity for PPARγ, with Ki values of 26 and 77 μM, respectively, the same assay.
