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Oleamid
ODA · 9-OCTADECENAMIDE · (Z)-9-Octadecenamide · Oleic acid amide · OLEAMID · OLEYLAMIDE · CIS-9-OCTADECENAMIDE · 9-Octadecenamide,(Z)-
Identifikatoren & physikalische Daten
| CAS No. | 301-02-0 |
|---|---|
| Summenformel | C18H35NO |
| Durchschnittliche Molmasse | 281,5 g/mol |
| Monoisotopische Masse | 281,27186474 g/mol |
| SMILES | CCCCCCCC/C=C\CCCCCCCC(N)=O |
| InChIKey | FATBGEAMYMYZAF-KTKRTIGZSA-N |
| PubChem CID | 5283387 |
| ChEMBL | CHEMBL15927 |
| ChEBI | CHEBI:116314 |
| EC No. | 206-103-9 |
| DTXSID | DTXSID6027137 |
| Lokaler Name | Oleamid |
Chemische & physikalische Eigenschaften
| XLogP | 6,6 |
|---|---|
| Polarare Oberfläche (TPSA) | 43,1 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 1 |
| Frei drehbare Bindungen | 15 |
| Schwere Atome | 20 |
| Formalladung | 0 |
| Komplexität | 236 |
| Dichte | 0.940.94 g/cm3 |
| Color/Form | IVORY-COLORED POWDER |
| Löslichkeit | INSOL IN WATERSOL IN ETHER, HOT ALCOHOLSoluble in chloroform (50 mg/ml), ethanol (100 mM), DMSO (~14 mg/ml), and DMF (~14 mg/ml)Insoluble in water. |
| Schmelzpunkt | 76 °C102 - 104 °C70°C |
| Dampfdruck | 0.0000012 [mmHg] |
| Physical Description | Large CrystalsDry PowderLiquidOther SolidIvory-colored solid[HSDB] |
| Kovats Retention Index | 237523973265 |
| Siedepunkt | 433.3±24.0 °C(Predicted) |
| Lagerbedingungen | -20°C |
| pKa (Säurekonstante) | 16.61±0.40(Predicted) |
| Aggregatzustand | Solid |
| Farbe | White to off-white |
| Stabilität | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month. |
| Kosmetik-Inhaltsstoffe Funktionen | OPACIFYINGVISCOSITY CONTROLLING |
| InChI | 1S/C18H35NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H2,19,20)/b10-9- |
| InChIKey | FATBGEAMYMYZAF-KTKRTIGZSA-N |
| SMILES | CCCCCCCC\C=C/CCCCCCCC(N)=O |
| LogP (Verteilungskoeffizient) | 6.882 (est) |
| CAS Datenbank | 301-02-0(CAS DataBase Reference) |
| NIST chemische Informationen | 9-Octadecenamide, (z)-(301-02-0) |
| EPA chemische Informationen | Oleamide (301-02-0) |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 42.7% (470 of 1101) of reports.WarningH315 (12.1%): Causes skin irritation [Warning Skin corrosion/irritation]H319 (12.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H335 (12.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]H413 (40.2%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard]P261, P264, P264+P265, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 1101 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Reported as not meeting GHS hazard criteria per 470 of 1101 reports by companies.There are 7 notifications provided by 631 of 1101 reports by companies with hazard statement code(s).Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| Regulatorische Informationen | Chemical: 9-Octadecenamide, (Z)-9-Octadecenamide, (9Z)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 9-Octadecenamide, (9Z)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)9-Octadecenamide, (9Z)-: Does not have an individual approval but may be used under an appropriate group standard |
| Weitere Sicherheitsinformationen | IMAP assessments - 9-Octadecenamide, (Z)-: Human health tier I assessment |
| Gefahrenübersicht | Contact urticarial reaction reported within 20 minutes of open patch testEmergency treatment: Irritants[HSDB] Causes mild skin and eye irritation in rabbits |
Anwendungen & Verwendung
Verwenden
Oleamide has been used as a supplement in glucose and galactose media to prevent the rescue of galactose-induced Leigh syndrome (LS).