N-Arachidonoyl glycine
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Grundinformationen
- CAS
179113-91-8- Standard-SMILES
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCC(=O)O- InChIKey
YLEARPUNMCCKMP-DOFZRALJSA-N- Summenformel
- C22H35NO3
- Durchschnittliche Molmasse
- 361,526 g/mol
- Monoisotopische Masse
- 361,26169398
Namen und Bezeichner
- Bevorzugter Name
- N-Arachidonoyl glycine
- IUPAC
- N-[(5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoyl]glycine
- Englischer Name
- NAGLY
- Summenformel
- C22H35NO3
- Molmasse
- 361.52
Namen und Synonyme
N-ARACHIDONOYL GLYCINENAGLYArachidonyl GlycineNAGly, CID 5283389ARACHIDONOYL GLYCINEN-ARACHIDONYL GLYCINEN Arachidonylglycine,NArachidonylglycineN-Arachidonoyl glycine (solution in ethanol)N-(1-OXO-5Z,8Z,11Z,14Z-EICOSATETRAENYL)GLYCINE2-((5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenamido)acetic acid
Datenbank-Bezeichner
- CAS
179113-91-8- PubChem CID
- 5283389
- DTXSID
DTXSID5045124- ChEMBL
CHEMBL161343- ChEBI
CHEBI:58961- UNII
- 5PB56SQA6E
- Nikkaji
- J1.404.839A
Eigenschaften
Physikochemische Eigenschaften
- Siedepunkt
- 560.9 · 560.9±50.0 °C(Predicted)
- Dichte
- 0.985 · 0.985±0.06 g/cm3(Predicted)
- storage temp.
- 20 °C · −20°C
- Löslichkeit
- 5 mg/mL, · DMSO: >5 mg/mL, soluble
- Aggregatzustand
- waxy solid
- pka
- 3.58 · 3.58±0.10(Predicted)
- Farbe
- off-white
- Stabilität
- 2 years · Stable for 2 years from date of purchase as supplied. Product is subject to oxidation. Solutions in degassed DMSO may be stored at -20°C for up to 1 month.
- InChIKey
- YLEARPUNMCCKMP-DOFZRALJSA-N
- SMILES
- O=C(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)NCC(O)=O
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
Sicherheitsdaten
- wgk
- 3
- safety_code
- 22-24/25
- Hazard Classifications
- Carc. 2Eye Irrit. 2Skin Irrit. 2STOT SE 3
Chemie und Industrie
Anwendungen
BeschreibungArachidonoyl glycine (N-arachidonyl glycine; NAGly) has been isolated from cell cultures treated with arachidonoyl ethanolamide (AEA; anandamide), from extracts of mammalian brain, and has also been synthesized as an analog of AEA for structure/activity testing. NAGly may be produced endogenously via oxidation of AEA, or by transacylation of arachidonoyl CoA. NAGly is reported to have analgesic activities in whole animal experiments. Since it seems to be a very poor ligand for the CB1 receptor, these effects are probably mediated via other signaling pathways.
VerwendenArachidonoyl glycine (N-arachidonyl glycine; NAGly) has been isolated from cell cultures treated with arachidonoyl ethanolamide (AEA; anandamide), from extracts of mammalian brain, and has also been synthesized as an analog of AEA for structure/activity testing. NAGly may be produced endogenously via oxidation of AEA, or by transacylation of arachidonoyl CoA. NAGly is reported to have analgesic activities in whole animal experiments. Since it seems to be a very poor ligand for the CB1 receptor, these effects are probably mediated via other signaling pathways.[Cayman Chemical]
Anbieter34 Anbieter
武汉敬康恩生物医药科技有限公司13720134139 086-15871494362 13720134139 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
上海优宁维生物科技股份有限公司15921930842 15921930842 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
江苏艾康生物医药研发有限公司025-025-66113011 15955137747 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
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