(-)-5-[3-(tert-Butylamino)-2-hydroxypropoxy]-3,4-dihydronaphthalin-1(2H)-onhydrochlorid

LEVOBUNOLOL HCL · AG-901 · w7000a · betagan · gotensin · vistagan · (-)-rochlorid · l-bunololhydrochloride

https://huagongshe.com/de/chemical/5284409

Molekülstruktur von (-)-5-[3-(tert-Butylamino)-2-hydroxypropoxy]-3,4-dihydronaphthalin-1(2H)-onhydrochlorid

Identifikatoren & physikalische Daten

CAS No.	27912-14-7
Summenformel	C17H26ClNO3
Durchschnittliche Molmasse	327,8 g/mol
Monoisotopische Masse	327,16012137 g/mol
SMILES	CC(C)(C)NC[C@H](O)COc1cccc2c1CCCC2=O.Cl
InChIKey	DNTDOBSIBZKFCP-YDALLXLXSA-N
PubChem CID	5284409
ChEMBL	CHEMBL1201177
ChEBI	CHEBI:6439
EC No.	248-725-3
DTXSID	DTXSID6020777
Lokaler Name	(-)-5-[3-(tert-Butylamino)-2-hydroxypropoxy]-3,4-dihydronaphthalin-1(2H)-onhydrochlorid

Chemische & physikalische Eigenschaften

Polarare Oberfläche (TPSA)	58,6
H-Brücken-Donoren	3
H-Brücken-Akzeptoren	4
Frei drehbare Bindungen	6
Schwere Atome	22
Formalladung	0
Komplexität	350
Human Drugs	FDA approved drugs -> Active ingredient
Schmelzpunkt	209-211°
Lagerbedingungen	Amber Vial, Refrigerator, Under inert atmosphere
Löslichkeit	DMSO (Slightly), Methanol (Slightly), Water (Sparingly)
Aggregatzustand	Solid
Farbe	White to Off-White
Stabilität	Light Sensitive

Sicherheit & Vorschriften

GHS-Einstufung	This chemical does not meet GHS hazard criteria for 2.1% (1 of 48) of reports.WarningH302 (97.9%): Harmful if swallowed [Warning Acute toxicity, oral]P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 48 reports by companies from 3 notifications to the ECHA C&L Inventory.
Hazard Classes and Categories	Acute Tox. 4 (97.9%)
Zollcode	2922504500

Anwendungen & Verwendung

Beschreibung

Levobunolol hydrochloride is a non-selective β-adrenergic blocker useful in the treatment of glaucoma. Worldwide, it represents the sixth B-blocker to be launched for this indication.

Verwenden

Anti-adrenergic (β-receptor).