Genistin
GENISTEIN-7-O-GLUCOSIDE · Genistoside · GENISTEIN-7-GLUCOSIDE · 7-O-BETA-D-GLUCOPYRANOSIDE · genistein 7-O-β-D-glucoside · 5-hydroxy-3-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one · GENISTIN · NSC 5112
Identifikatoren & physikalische Daten
| CAS No. | 529-59-9 |
|---|---|
| Summenformel | C21H20O10 |
| Durchschnittliche Molmasse | 432,38 g/mol |
| SMILES | O=c1c(-c2ccc(O)cc2)coc2cc(OC3OC(CO)C(O)C(O)C3O)cc(O)c12 |
| PubChem CID | 5284639 |
| ChEMBL | CHEMBL1364260 |
| ChEBI | CHEBI:91655 |
Chemische & physikalische Eigenschaften
| Schmelzpunkt | 254°C |
|---|---|
| Siedepunkt | 256 °C |
| Dichte | 1.642±0.06 g/cm3(Predicted) |
| Lagerbedingungen | 2-8°C |
| Löslichkeit | DMSO: 10 mg/mL |
| pKa (Säurekonstante) | 6.12±0.20(Predicted) |
| Aggregatzustand | Solid |
| Farbe | Off-white |
| Biologische Quelle | Glycine max (soybean) |
| Merck | 13,4402 |
| BRN | 64479 |
| Stabilität | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 week. |
| Hauptanwendungen | food and beverages |
| Kosmetik-Inhaltsstoffe Funktionen | ANTIOXIDANTSKIN CONDITIONING |
| InChIKey | ZCOLJUOHXJRHDI-CMWLGVBASA-N |
| SMILES | OC[C@H]1O[C@@H](Oc2cc(O)c3C(=O)C(=COc3c2)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O |
| LogP (Verteilungskoeffizient) | 0.790 (est) |
Sicherheit & Vorschriften
| F | 10 |
|---|---|
| Wassergefährdungsklasse (WGK) | 3 |
| Zollcode | 29389090 |
| RTECS-Nr. | DJ3093000 |
| Sicherheitshinweise (S) | 22-24/25 |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Beschreibung
Genistin is a natural isoflavone isolated from legumes, including soy and kudzu. It is a phytoestrogen, as it stimulates the growth of estrogen-dependent human breast cancer cells in vivo. Like other isoflavones, genistin promotes the proliferation of bone marrow stromal cells and osteoblasts and suppresses bone turnover. It also increases bone formation in collagen matrix in vivo.
Verwenden
Genistin has been used for immune reactivity against influenza viruses in vitro and as an internal standard in isoflavones quantification.