Grundinformationen
- CAS
651-06-9- Standard-SMILES
COc1cnc(NS(=O)(=O)c2ccc(N)cc2)nc1- InChIKey
GPTONYMQFTZPKC-UHFFFAOYSA-N- Summenformel
- C11H12N4O3S
- Durchschnittliche Molmasse
- 280,31 g/mol
- Monoisotopische Masse
- 280,06301143
Überblick
Sulfamethoxydiazine is a sulfonamide consisting of pyrimidine having a methoxy substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 2-position. It has a role as an antiinfective agent, a leprostatic drug and a renal agent. It is a sulfonamide, a member of pyrimidines and a sulfonamide antibiotic. It is functionally related to a sulfanilamide.
Namen und Bezeichner
- Bevorzugter Name
- Sulfameter
- IUPAC
- 4-amino-N-(5-methoxypyrimidin-2-yl)benzenesulfonamide
- Lokaler Name
- Sulfametoxydiazin
- Englischer Name
- Sulfameter
- Summenformel
- C11H12N4O3S
- Molmasse
- 280.3
Namen und Synonyme
sulfameter651-06-9Sulfamethoxydiazine4-amino-N-(5-methoxypyrimidin-2-yl)benzenesulfonamideSulfametoxydiazineSulfamethoxypyrimidineSulphamethoxydiazineSullaSulfamethoxineSulfametinUltraxSulphameter
Weitere Namen anzeigen
SMDSulfaneter2-sulfanilamido-5-methoxypyrimidinesh613I-2586
Sulfa-5-methoxypyrimidineBayrenaSulfametoxidiazinaSolfametossidiazina4-Amino-N-(5-methoxy-2-pyrimidinyl)benzenesulfonamideAHR-857Benzenesulfonamide, 4-amino-N-(5-methoxy-2-pyrimidinyl)-Sulfametoxydiazinum
Datenbank-Bezeichner
- CAS
651-06-9- PubChem CID
- 5326
- DTXSID
DTXSID5023613- ChEMBL
CHEMBL1200359- ChEBI
CHEBI:53727- UNII
- 3L179F09D6
- EC Number
- 211-480-8
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 0,4
- Polarare Oberfläche (TPSA)
- 116 Ų
- H-Brücken-Donoren
- 2
- H-Brücken-Akzeptoren
- 7
- Frei drehbare Bindungen
- 4
- Schwere Atome
- 19
- Formalladung
- 0
- Komplexität
- 368
Experimentelle und physikochemische Eigenschaften
Drugs
Pharmaceuticals -> Antibiotics
Pharmaceuticals -> Listed in ZINC15
SpringerMaterials PropertiesFusion temperature
LogP0.41
Solubility>42 [ug/mL] (The mean of the results at pH 7.4)
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
Pharmaceuticals
Collision Cross Section
161.6 Ų [M+H]+ [CCS Type: TW; Method: calibrated with Waters Major Mix]
159 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
157.69 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
Physikochemische Eigenschaften
- Schmelzpunkt
- 214 · 214-216°C
- Siedepunkt
- 539.4 · 539.4±56.0 °C(Predicted)
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 69 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Other Safety InformationIMAP assessments - Benzenesulfonamide, 4-amino-N-(5-methoxy-2-pyrimidinyl)-: Human health tier I assessment
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Sicherheitsdaten
- wgk
- 2
- hs_code
- 29350090
- RTECS-Nr.
- WP0525000
- risk_code
- 36/37/38
- hazard_code
- Xi
- safety_code
- 26-36
- Speicherklasse
- 11 - Combustible Solids
- Hazard Classifications
- Eye Irrit. 2Skin Irrit. 2STOT SE 3
Chemie und Industrie
Pharmakologische Informationen
ATC CodeJ - Antiinfectives for systemic use
MeSH Pharmacological Classification
Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection.
Substances capable of killing agents causing urinary tract infections or of preventing them from spreading.
Substances that suppress Mycobacterium leprae, ameliorate the clinical manifestations of leprosy, and/or reduce the incidence and severity of leprous reactions.
Verwendung und Herstellung
Use ClassificationPharmaceuticals
Anwendungen
VerwendenSulfameter is an antibacterial.
Vor- und nachgelagerte Produkte
Vorgelagerte Rohstoffe
Anbieter100 Anbieter
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
成都彼样生物科技有限公司18108052721 · [email protected]
湖北金梭生物科技有限公司00123456789 · [email protected]
宁波季诺化学品有限公司0574-87314919 057487319282 · [email protected]
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