Grundinformationen
- Standard-SMILES
CCCCCCCC/C=C\CCCCCCCCN- InChIKey
QGLWBTPVKHMVHM-KTKRTIGZSA-N- Summenformel
- C18H37N
- Durchschnittliche Molmasse
- 267,5 g/mol
- Monoisotopische Masse
- 267,29260018
Überblick
promotes fusion of mouse A(9) fibroblasts; RN given refers to parent cpd with unspecified isomeric designation; structure
Namen und Bezeichner
- Bevorzugter Name
- Oleylamine
- IUPAC
- (Z)-octadec-9-en-1-amine
- Lokaler Name
- (Z)-Octadec-9-enylamin
- Englischer Name
- Oleylamine
- Summenformel
- C18H37N
- Molmasse
- 267.49
Namen und Synonyme
Weitere Namen anzeigen
Datenbank-Bezeichner
- CAS
112-90-3、1838-19-3- PubChem CID
- 5356789
- DTXSID
DTXSID8026933- ChEMBL
CHEMBL1976606- UNII
- ZDQ1JWQ8DT
- EC Number
- 204-015-5
- Nikkaji
- J59.382F
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 7,6
- Polarare Oberfläche (TPSA)
- 26 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 1
- Frei drehbare Bindungen
- 15
- Schwere Atome
- 19
- Formalladung
- 0
- Komplexität
- 175
Experimentelle und physikochemische Eigenschaften
Physical Description
Liquid; CBI
Liquid; mp = 10-20 deg C; [IUCLID] Light yellow pasty liquid with an amine-like odor (mp = 15-30 deg C); [ECHA] Slightly beige paste; [MSDSonline]
Physikochemische Eigenschaften
- Schmelzpunkt
- 18 · 18-26 °C (lit.)
- Siedepunkt
- 348 · 348-350 °C (lit.)
- Dichte
- 0.813 g/mL · 0.813 g/mL at 25 °C (lit.)
- Dampfdruck
- 8 mm · 8 mm Hg ( 135 °C)
- Brechungsindex
- 20 · n20/D 1.4596(lit.)
- Flammpunkt
- 310 °F · 310 °F
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- Aggregatzustand
- liquid
- pka
- 10.67 · 10.67±0.10(Predicted)
- Farbe
- colorless
- Geruch (Odor)
- slt amine/lemon odor
- Wasserlöslichkeit
- insoluble
- BRN
- 1723960 · 1723960
- Stabilität
- Stable. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents.
- Kosmetik-Inhaltsstoffe Funktionen
- ANTISTATIC
- InChI
- 1S/C18H37N/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19/h9-10H,2-8,11-19H2,1H3/b10-9-
- InChIKey
- QGLWBTPVKHMVHM-MDZDMXLPSA-N
- SMILES
- [H]\C(CCCCCCCC)=C(/[H])CCCCCCCCN
- LogP
- 7.78 · 7.780 (est)
- CAS Datenbank
- 112 · 112-90-3(CAS DataBase Reference)
- EPA chemische Informationen
- Oleylamine (112-90-3)
Sicherheit und Regulatorisches
GHS-Klassifizierung
GHS Classification
Danger
H302: Harmful if swallowed [Warning Acute toxicity, oral]
P260, P261, P264, P270, P271, P273, P280, P301+P316, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P319, P321, P330, P331, P363, P391, P403+P233, P405, and P501 (click each P-code to see the statement)
This chemical does not meet GHS hazard criteria for 3.7% (60 of 1620) of reports.
Danger
H302 (90.6%): Harmful if swallowed [Warning Acute toxicity, oral]
Gefahrenhinweise
Regulatory Information
Chemical: 9-Octadecen-1-amine, (Z)-
9-Octadecen-1-amine, (9Z)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 9-Octadecen-1-amine, (9Z)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Oleyl amine: Does not have an individual approval but may be used under an appropriate group standard
Hazards Summary
Concentrations of 1.5% and 3% in corn oil produced moderate to severe skin irritation in rats; Post-implantation mortality observed in mice following single oral dose on ninth day of pregnancy; No evidence of teratogenicity in rats or rabbits at gavage doses maternally toxic; No evidence of mutagenicity; [IUCLID] Corrosive to rabbit skin; Effects in 28-day gavage study with rats include abnormal gait, decrease in weight gain, and minor toxicity to the liver and kidneys; No histopathological effects observed in reproductive organs; No evidence of mutagenicity, teratogenicity, or developmental toxicity; [ECHA] Causes burns; Harmful by ingestion, inhalation, and skin absorption; Inhalation can cause corrosive effects on the upper respiratory tract and lungs; [Aldrich MSDS]
DOT Hazard Classification
Oleylamine
Marine pollutant
Hazard Classes and Categories
Acute Tox. 4 (90.6%)
Acute toxicity - category 4
Acute toxicity (Oral) - Category 4
Acute Tox. 4
Toxikologische Informationen
TSCA Test Submissions
The mutagenicity of (Z)-9-octadecenylamine (ODA) was evaluated in Salmonella tester strains TA98, TA100, TA1535, TA1537 and TA1538, both in the presence and absence of added metabolic activation by Aroclor-induced rat liver S9 fraction. Based on preliminary bacterial toxicity determinations, ODA, diluted with acetone, was tested for mutagenicity at concentrations up to 20 ug/plate for nonactivated cultures and concentrations up to 200 ug/plate for activated cultures using the plate incorporation method. ODA did not cause a positive response in any of the bacterial tester strains, either with or without metabolic activation.
Sicherheitsdaten
- wgk
- 2
- tsca
- TSCA listed
- ridadr
- UN 2735 8/PG 2
- hs_code
- 29215900
- RTECS-Nr.
- RG4130000
- risk_code
- 34-22-50/53
- Toxizität
- LD50 intraperitoneal in mouse: 888mg/kg
- hazard_code
- C,N
- safety_code
- 26-36/37/39-45-24/25
- hazard_class
- 8
- packing_group
- III
- Speicherklasse
- 8A - Combustible corrosive hazardous materials
- Giftige Stoffe Daten
- 112-90-3(Hazardous Substances Data)
- Hazard Classifications
- Acute Tox. 4 OralAquatic Acute 1Aquatic Chronic 1Asp. Tox. 1Eye Dam. 1Skin Corr. 1BSTOT RE 2STOT SE 3
Chemie und Industrie
Verwendung und Herstellung
Uses
Used as an intermediate, surfactant in textile production, and cosmetic ingredient; Amine and organic salts: Used as petroleum product and lubricant additives, corrosion inhibitors (i.e. in oil fields), ore flotation reagents, wetting agents for asphalt, and emulsifiers; [HSDB] Used in the EU as intermediate, flotation agent for metals, lubricant in metal processing, fuel additive, corrosion inhibitor, and antistatic agent for paints; [ECHA]
Petroleum Production and Refining [Category: Industry]
...SERIES OF PRIMARY, SECONDARY, & ALIPHATIC AMINES, ORG SUBSTITUTED AMMONIA DERIV.../USED AS/ CORROSION INHIBITORS, ORE FLOTATION AGENTS, TEXTILE FINISHING AGENTS, ASPHALT ANTISTRIPPING AGENTS, RUBBER COMPOUNDING, COLOR PARTICLE DISPERSION, PETROLEUM PRODUCT ADDITIVES, CHEMICAL INTERMEDIATES /ALAMINE/
...SERIES OF STRAIGHT CHAIN AMINES...FROM C12 THROUGH C22... /WHICH/ ARE STRONGLY HYDROPHOBIC & ARE BIODEGRADABLE. .../USED AS/ CATIONIC INTERMEDIATES; REMOVAL OF MOISTURE FROM SURFACES /KEMAMINES/
CHEM INT FOR QUATERNARY AMMONIUM SALTS
CHEM INT FOR OLEYL DIAMINE & ETHOXYLATED OLEYLAMINE
U.S. Exports
(1979) No Data
(1981) No Data
U.S. Imports
(1979) No Data
(1981) No Data
U.S. Production
2023: 8,500,000 - <10,000,000 lb
(1979) 2.24X10+9 GRAMS
(1981) 2.49X10+9 GRAMS
General Manufacturing Information
All Other Basic Organic Chemical Manufacturing
9-Octadecen-1-amine, (9Z)-: ACTIVE
Anwendungen
VerwendenOleylamine is a long-chain primary alkylamine broadly used in the synthesis of metallic nanostructures. A variety of metallic nanostructures including Au, Ag, Pt, Pd, and their alloy has been synthesized in the presence of oleylamine. It has several important functions in the synthesis of metallic nanostructure. Oleylamine can simultaneously function as a solvent for the reaction mixture and stabilizing agent for metallic nanostructures. In addition, oleylamine has a boiling point of 364 °C; therefore, it can be used to synthesize metallic nanostructures at high temperatures.
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