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59632-76-7C=C1C(=O)OC2/C=C(/C)CC/C=C(\C(=O)O)CC/C=C(\C)CCC12SORYERHBQFTRIK-XMLQBHOOSA-N59632-76-7DTXSID20418461BeschreibungAnisomelic acid: a cembrane-type macrocyclic diterpenoid possesses both anticancer and antiviral activityAnisomelic acid (AA) is one of the principle bioactive compounds isolated from the plant Anisomeles malabarica. It is a membrane-type macrocyclic diterpenoid that presents potent cytotoxicity. It possesses both anticancer and antiviral activity. Researchers have studied the mode of action of AA-mediated apoptosis, indicating that AA inhibits the expression of the E6 and E7 viral proteins. In addition, AA is also effective in inducing apoptosis in other HPV-positive cervical cancer cells, with a high degree of specificity to HPV-positive cells and insignificant effects on HPV-negative cells[1-2].
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