CAS 24683-26-9 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid ethylester 1,1-dioxide (HCID 54679348)

Namen und Bezeichner

Bevorzugter Name: 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid ethylester 1,1-dioxide
IUPAC: ethyl 4-hydroxy-2-methyl-1,1-dioxo-1lambda6,2-benzothiazine-3-carboxylate
Lokaler Name: Ethyl-4-hydroxy-2-methyl-2H-1,2-benzothiazin-3-carboxylat-1,1-dioxid
Englischer Name: Ethyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide
Summenformel: C12H13NO5S
Molmasse: 283.3

Namen und Synonyme

24683-26-9Ethyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxideEINECS 246-403-7EAD64Z1YS14-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid ethylester 1,1-dioxide2H-1,2-Benzothiazine-3-carboxylic acid, 4-hydroxy-2-methyl-, ethyl ester, 1,1-dioxideDTXSID30179415EC 246-403-7MELOXICAM IMPURITY A [EP IMPURITY]PIROXICAM IMPURITY K [EP IMPURITY]4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic Acid Ethyl Ester 1,1-DioxideMELOXICAM IMPURITY A (EP IMPURITY)

Weitere Namen anzeigen

2-METHYL-4-HYDROXY-2H-1,2-BENZOTHIAZINE-1,1-DIOXIDE-3-CARBOXYLIC ACID ETHYL ESTEREcMetAP1-IN-1Piroxicam Impurity K2-Methyl-4-hydroxy-2H-1Meloxicam USP Related Compound AEthyl 4-Hydroxy-2-methyl-2H-1,2-benMeloxicaM IMpurity A(EP) (USP RC A)Meloxicam usp RC A/Meloxicam EP IMP A2-benzothiazine-3-carboxylic acid ethyl ester-1Piroxicam EP Impurity K(Meloxicam EP Impurity A)

PIROXICAM IMPURITY K (EP IMPURITY)RefChem:523747DTXCID60101906Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide2-Methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxylic acid ethyl ester 1,1-dioxideMFCD00190168ethyl 4-hydroxy-2-methyl-1,1-dioxo-1lambda6,2-benzothiazine-3-carboxylate2-Methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxylic acid ethyl ester-1,1-dioxide

Datenbank-Bezeichner

CAS: 24683-26-9
PubChem CID: 54679348
DTXSID: DTXSID30179415
ChEMBL: CHEMBL598364
UNII: EAD64Z1YS1
EC Number: 246-403-7

Eigenschaften

Berechnete Struktureigenschaften

XLogP: 3,2
Polarare Oberfläche (TPSA): 92,3 Å²
H-Brücken-Donoren: 1
H-Brücken-Akzeptoren: 6
Frei drehbare Bindungen: 3
Schwere Atome: 19
Formalladung: 0
Komplexität: 505

Physikochemische Eigenschaften

Schmelzpunkt: 140 · 140-144 °C (lit.)
Siedepunkt: 448.1 · 448.1±55.0 °C(Predicted)
Dichte: 1.458 · 1.458±0.06 g/cm3(Predicted)
storage temp.: 2 · 2-8°C
Löslichkeit: Dichloromethane (Slightly), DMSO (Slightly), Methanol (Slightly)
Aggregatzustand: solid
pka: 4.5 · 4.50±1.00(Predicted)
InChI: 1S/C12H13NO5S/c1-3-18-12(15)10-11(14)8-6-4-5-7-9(8)19(16,17)13(10)2/h4-7,14H,3H2,1-2H3
InChIKey: QWTNANUGXZEPFQ-UHFFFAOYSA-N
SMILES: CCOC(=O)C1=C(O)c2ccccc2S(=O)(=O)N1C
CAS Datenbank: 24683 · 24683-26-9(CAS DataBase Reference)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 5 Einträge

Danger

H331 (89.4%): Toxic if inhaled [Danger Acute toxicity, inhalation]

P261, P271, P304+P340, P316, P321, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 47 reports by companies from 7 notifications to the ECHA C&L Inventory.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Regulatory InformationStatus: Active Update: 01-04-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/18782；Status: Active Update: 09-03-2012 https://echa.europa.eu/registration-dossier/-/registered-dossier/6294

Hazard Classes and CategoriesAcute Tox. 3 (89.4%)

Regulatorische Informationen

Regulatory InformationStatus: Active Update: 01-04-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/18782；Status: Active Update: 09-03-2012 https://echa.europa.eu/registration-dossier/-/registered-dossier/6294

Sicherheitsdaten

wgk: 2
ridadr: UN 2811 6.1/PG 2
hs_code: 2934990002
RTECS-Nr.: DL0710425
risk_code: 23
hazard_code: T
safety_code: 45
Speicherklasse: 6.1A - Combustible acute toxic Cat. 1 and 2very toxic hazardous materials
Hazard Classifications: Acute Tox. 3 Inhalation