CAS 14024-61-4 Palladium acetylacetonate (HCID 5486778)

Namen und Bezeichner

Bevorzugter Name: Palladium acetylacetonate
IUPAC: bis((Z)-4-oxopent-2-en-2-olate);palladium(2+)

Namen und Synonyme

14024-61-4RefChem:858315PALLADIUM(2+) ION BIS(4-OXOPENT-2-EN-2-OLATE)Palladium acetylacetonatePalladium(II) acetylacetonatePalladium bis(acetoacetonate)Pd(acac)2Bis(acetylacetonato)palladium(Z)-4-oxopent-2-en-2-olate;palladium(2+)Palladium-2,4-pentanedionatePalladium, bis(2,4-pentanedionato-kappaO2,kappaO4)-, (SP-4-1)-palladium (II) acetylacetonate

Weitere Namen anzeigen

EINECS 237-859-8Palladium, bis(2,4-pentanedionato)-NSC 187660Palladium (II) di(4-oxopent-2-en-2-oate)palladium(II)acetylacetonate6G7QUC3M5JSCHEMBL144097Palladium, bis(2,4-pentanedionato-O,O')-, (SP-4-1)-

Datenbank-Bezeichner

CAS: 14024-61-4
PubChem CID: 5486778
UNII: 6G7QUC3M5J
EC Number: 237-859-8

Eigenschaften

Berechnete StruktureigenschaftenWird ergänzt

Polarare Oberfläche (TPSA): 80,3 Å²
H-Brücken-Donoren: 0
H-Brücken-Akzeptoren: 4
Frei drehbare Bindungen: 2
Schwere Atome: 15
Formalladung: 0
Komplexität: 90

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 5 Einträge

Danger

H228 (61.5%): Flammable solid [Danger Flammable solids]；H251 (26.6%): Self-heating; may catch fire [Danger Self-heating substances and mixtures]；H302 (25.7%): Harmful if swallowed [Warning Acute toxicity, oral]；H315 (36.7%): Causes skin irritation [Warning Skin corrosion/irritation]；H317 (24.8%): May cause an allergic skin reaction [Warning Sensitization, Skin]；H318 (24.8%): Causes serious eye damage [Danger Serious eye damage/eye irritation]；H319 (73.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (34.9%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]；H400 (24.8%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]；H410 (24.8%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

P210, P235, P240, P241, P261, P264, P264+P265, P270, P271, P272, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P370+P378, P391, P403+P233, P405, P407, P410, P413, P420, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 109 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Regulatory Information · 3 Einträge

Chemical: Palladium, bis(2,4-pentanedionato-O,O')-, (SP-4-1)-

Status: Active Update: 25-11-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/18885

Palladium, bis(2,4-pentanedionato-.kappa.O,.kappa.O')-, (SP-4-1)-: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Palladium, bis(2,4-pentanedionato-O,O')-, (SP-4-1)-: Human health tier I assessment；IMAP assessments - Palladium, bis(2,4-pentanedionato-O,O')-, (SP-4-1)-: Environment tier I assessment

Hazard Classes and CategoriesFlam. Sol. 1 (61.5%)；Self-heat. 1 (26.6%)；Acute Tox. 4 (25.7%)；Skin Irrit. 2 (36.7%)；Skin Sens. 1 (24.8%)；Eye Dam. 1 (24.8%)；Eye Irrit. 2 (73.4%)；STOT SE 3 (34.9%)；Aquatic Acute 1 (24.8%)；Aquatic Chronic 1 (24.8%)

Toxikologische Informationen

Health Effects · 2 Einträge

Contact with palladium may cause palladium sensitivity and allergy. Animal studies have shown that palladium may damage the liver and kidney. (L798)

Toxicity Summary · 2 Einträge

Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, and interact with functional groups of macromolecules, such as proteins or DNA. Palladium complexes binding to DNA and RNA leads to strand breakage. Palladium ions are able to inhibit most major cellular functions, including DNA and RNA synthesis. Palladium compounds have been shown to bind to and inhibit various enzymes, including creatine kinase and prolyl hydroxylase. (L798)

Signs and Symptoms · 2 Einträge

Skin contact with palladium may cause contact dermatitis, erythema, and oedema. (L798)

Carcinogen Classification · 2 Einträge

No indication of carcinogenicity to humans (not listed by IARC).

Regulatorische Informationen

Regulatory Information · 3 Einträge

Chemical: Palladium, bis(2,4-pentanedionato-O,O')-, (SP-4-1)-

Status: Active Update: 25-11-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/18885

Palladium, bis(2,4-pentanedionato-.kappa.O,.kappa.O')-, (SP-4-1)-: Does not have an individual approval but may be used under an appropriate group standard

Chemie und Industrie

Pharmakologische Informationen

Metabolism/Metabolites · 2 Einträge

Palladium may be absorbed through oral, dermal, and inhalation exposure. Once in the body it distributes to the kidney, liver, spleen, lymph nodes, adrenal gland, lung and bone. Palladium's ability to form complexes allows it the bind to amino acids, proteins, DNA, and other macromolecules. Palladium and its metabolites are excreted in the urine and faeces. (A21)