HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Mastoparan X
MP-X · MASTOPARAN X · INWKGIAAMAKKLL-NH2 · ILE-ASN-TRP-LYS-GLY-ILE-ALA-ALA-MET-ALA-LYS-LYS-LEU-LEU-NH2 · H-ILE-ASN-TRP-LYS-GLY-ILE-ALA-ALA-MET-ALA-LYS-LYS-LEU-LEU-NH2 · L-Leucinamide, L-isoleucyl-L-asparaginyl-L-tryptophyl-L-lysylglycyl-L-isoleucyl-L-alanyl-L-alanyl-L-methionyl-L-alanyl-L-lysyl-L-lysyl-L-leucyl-
Identifikatoren & physikalische Daten
| CAS No. | 72093-22-2 |
|---|---|
| Summenformel | C73H126N20O15S |
| Durchschnittliche Molmasse | 1.556 g/mol |
| Monoisotopische Masse | 1.554,94322457 g/mol |
| SMILES | CC[C@H](C)C(NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)[C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O |
| InChIKey | FYJKBFOGJAVCAL-MRBAVNCWSA-N |
| PubChem CID | 5488554 |
| EC No. | 686-479-2 |
Chemische & physikalische Eigenschaften
| XLogP | 0,4 |
|---|---|
| Polarare Oberfläche (TPSA) | 610 |
| H-Brücken-Donoren | 20 |
| H-Brücken-Akzeptoren | 20 |
| Frei drehbare Bindungen | 54 |
| Schwere Atome | 109 |
| Formalladung | 0 |
| Komplexität | 2.970 |
| Siedepunkt | 1797.4±65.0 °C(Predicted) |
| Dichte | 1+-.0.06 g/cm3(Predicted) |
| Lagerbedingungen | -15°C |
| Löslichkeit | DMF: 25 mg/mlDMSO: 25 mg/mlEthanol: 50 mg/mlPBS (pH 7.2): 1 mg/ml |
| Aggregatzustand | Lyophilized solid. |
| pKa (Säurekonstante) | 13.24±0.46(Predicted) |
| Farbe | White to off-white |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]P233, P260, P261, P271, P272, P280, P284, P302+P352, P304+P340, P321, P333+P317, P342+P316, P362+P364, P403, and P501 (click each P-code to see the statement)The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory. |
|---|---|
| Hazard Classes and Categories | Skin Sens. 1 (100%) |
| Sicherheitshinweise (S) | 22-24/25 |
Anwendungen & Verwendung
Verwenden
Has effects similar to mastoparan; binds with high affinity to calmodulin and inhibits sarcoplasmic reticulum calcium-ATPase