Gepirone monohydrochloride
Grundinformationen
- CAS
83928-66-9- Standard-SMILES
CC1(C)CC(=O)N(CCCCN2CCN(c3ncccn3)CC2)C(=O)C1.Cl- InChIKey
DGOCVISYYYQFEP-UHFFFAOYSA-N- Summenformel
- C19H30ClN5O2
- Durchschnittliche Molmasse
- 395,9 g/mol
- Monoisotopische Masse
- 395,2088029
Überblick
Gepirone hydrochloride is the hydrochloride salt of gepirone. It is a prescription medicine used to treat adults with a certain type of depression called major depressive disorder. It has a role as an antidepressant, an anxiolytic drug and a serotonergic agonist. It contains a gepirone(1+).
Namen und Bezeichner
- Bevorzugter Name
- Gepirone monohydrochloride
- IUPAC
- 4,4-dimethyl-1-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]piperidine-2,6-dione;hydrochloride
- Englischer Name
- Gepirone hydrochloride
- Summenformel
- C19H30ClN5O2
- Molmasse
- 395.9268
Namen und Synonyme
gepirone monohydrochlorideRefChem:142962GEPIRONE HYDROCHLORIDEGepirone HCl83928-66-9TravivoExxuaGepirone ERGepirone hydrochloride [USAN]BMY 13805-1Org 33062TGFK07AD
Weitere Namen anzeigen
RRSYY(Avadomide)-6GepironeHydrochloride2,6-Piperidinedione,4,4-dimethyl-1-[4-[4-(2- pyrimidinyl)-1-piperazinyl]butyl]-,monohydrochloride2,6-Piperidinedione, 4,4-dimethyl-1-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-, hydrochloride (1:1)
ORG-3306280C9L8EP6VCHEMBL1204187VarizaBMY-13805-14,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione hydrochlorideGepirone hydrochloride (USAN)3,3-Dimethyl-1-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)glutarimide monohydrochloride
Datenbank-Bezeichner
- CAS
83928-66-9- PubChem CID
- 55190
- DTXSID
DTXSID30232812- ChEMBL
CHEMBL1204187
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 69,6 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 6
- Frei drehbare Bindungen
- 6
- Schwere Atome
- 27
- Formalladung
- 0
- Komplexität
- 476
Experimentelle und physikochemische Eigenschaften
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
Physikochemische Eigenschaften
- Schmelzpunkt
- 192.5 · 192.5-195.5 °C
- Löslichkeit
- 2 O: · H2O: 2 mg/mL, clear
- Aggregatzustand
- powder
- Farbe
- white to beige
- InChI
- InChI=1S/C19H29N5O2.ClH/c1-19(2)14-16(25)24(17(26)15-19)9-4-3-8-22-10-12-23(13-11-22)18-20-6-5-7-21-18;/h5-7H,3-4,8-15H2,1-2H3;1H
- InChIKey
- DGOCVISYYYQFEP-UHFFFAOYSA-N
- SMILES
- N1(CCCCN2CCN(C3=NC=CC=N3)CC2)C(=O)CC(C)(C)CC1=O.[H]Cl
Sicherheit und Regulatorisches
Sicherheitsdaten
- Alarmwort
- Warnung
- Gefahrenhinweise
- Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code H302
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems.
Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here.
Endogenous compounds and drugs that bind to and activate SEROTONIN RECEPTORS. Many serotonin receptor agonists are used as ANTIDEPRESSANTS; ANXIOLYTICS; and in the treatment of MIGRAINE DISORDERS.
Anwendungen
VerwendenTranquilizer.
Anbieter32 Anbieter
陕西凯尔凯医药科技有限公司029-2148545164 17392779578 · [email protected]
武汉敬康恩生物医药科技有限公司13720134139 086-15871494362 13720134139 · [email protected]
奥夫仑医药（四川）有限公司17336178085 · [email protected]
成都佰洋科技有限责任公司02861777709 13308012069
济南启源生物科技有限公司18766124282; 18766124282 · [email protected]
Nantong Honglong Chemical Co., Ltd
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