HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
7-Chloro-6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
7-Chloro-6-fluoro-1-(4-fluorophenyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid · Difloxacin impurity G · Difloxacin EP Impurity G · Difloxacin EP Impurituy G · 1-(p-Fluoro-phenyl-6-fluoro-7-chloro-4-oxo-3-quinolinecarboxylic acid · 7-chloro-6-fluoro-1-(4-fluorophenyl)-4-oxo-3-quinolinecarboxylic acid · 7-Chloro-6-fluoro-1-(4-fluorophenyl)-4-oxoquinoline-3-carboxylic acid · 1-(4-Fluorophenyl)-6-fluoro-7-chloro-1,4-dihydro-4-oxoquinoline-3-carboxylicacid
Identifikatoren & physikalische Daten
| CAS No. | 98105-79-4 |
|---|---|
| Summenformel | C16H8ClF2NO3 |
| Durchschnittliche Molmasse | 335,69 g/mol |
| Monoisotopische Masse | 335,0160771 g/mol |
| SMILES | O=C(O)c1cn(-c2ccc(F)cc2)c2cc(Cl)c(F)cc2c1=O |
| InChIKey | FBAMWRYINJFGPJ-UHFFFAOYSA-N |
| PubChem CID | 57338 |
| ChEMBL | CHEMBL1472251 |
| DTXSID | DTXSID90275624 |
Chemische & physikalische Eigenschaften
| XLogP | 4,4 |
|---|---|
| Polarare Oberfläche (TPSA) | 57,6 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 6 |
| Frei drehbare Bindungen | 2 |
| Schwere Atome | 23 |
| Formalladung | 0 |
| Komplexität | 533 |
| Löslichkeit | >50.4 [ug/mL] (The mean of the results at pH 7.4)DMSO (Slightly), Methanol (Slightly, Heated) |
| Schmelzpunkt | 260-264℃ |
| Siedepunkt | 514℃ |
| Dichte | 1.584 |
| Flammpunkt | 265℃ |
| Lagerbedingungen | 2-8°C |
| Hauptanwendungen | pharmaceutical (small molecule) |
| InChI | 1S/C16H8ClF2NO3/c17-12-6-14-10(5-13(12)19)15(21)11(16(22)23)7-20(14)9-3-1-8(18)2-4-9/h1-7H,(H,22,23) |
| InChIKey | FBAMWRYINJFGPJ-UHFFFAOYSA-N |
| SMILES | Fc1ccc(cc1)[n]2c3c([c](c(c2)C(=O)O)=O)cc(c(c3)Cl)F |
Anwendungen & Verwendung
Verwenden
7-Chloro-6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid is a 1-arylated derivative of 1,4-dihydro-4-oxoquinoline-3-carboxylic acid with antibacterial activity.