6-Maleimidohexanoic acid (HCID 573683)

Namen und Bezeichner

Bevorzugter Name: 6-Maleimidohexanoic acid
IUPAC: 6-(2,5-dioxopyrrol-1-yl)hexanoic acid
Englischer Name: 6-Maleimidocaproic acid
Summenformel: C10H13NO4
Molmasse: 211.21

Namen und Synonyme

6-Maleimidocaproic acid6-Maleimidohexanoic acidRefChem:543501611-311-155750-53-36-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoic acid6-Maleimidocapronic acid1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo-6-(2,5-dioxopyrrol-1-yl)hexanoic acidMFCD00043140Maleimide-(CH2)5-COOHN-(5-Carboxypentyl)maleimide

Weitere Namen anzeigen

EMCA6-(2,5-Dioxo-2H-pyrrol-1(5H)-yl)hexanoic acidMalHex6-MaleimidocaproicAciMal-(CH2)5-COOH (EMCA)

N-Maleoyl-6-aminocaproic acidSCHEMBL43969CHEMBL47391CS-M1809N-(6-oxo-6-hydroxyhexyl)maleimideBP-20415PD127389SY030571

Datenbank-Bezeichner

CAS: 55750-53-3
PubChem CID: 573683
DTXSID: DTXSID10876051
ChEMBL: CHEMBL47391
ChEBI: CHEBI:176414
EC Number: 611-311-1
Nikkaji: J685.630F

Eigenschaften

Berechnete Struktureigenschaften

XLogP: 1,1
Polarare Oberfläche (TPSA): 74,7 Å²
H-Brücken-Donoren: 1
H-Brücken-Akzeptoren: 4
Frei drehbare Bindungen: 6
Schwere Atome: 15
Formalladung: 0
Komplexität: 291

Physikochemische Eigenschaften

Schmelzpunkt: 86 · 86-91 °C
Siedepunkt: 407.3 · 407.3±28.0 °C(Predicted)
Dichte: 1.285 · 1.285±0.06 g/cm3(Predicted)
storage temp.: 2 · 2-8°C
Löslichkeit: DMSO (Slightly), Ethyl Acetate (Slightly)
Aggregatzustand: Powder
pka: 4.74 · 4.74±0.10(Predicted)
Farbe: White to pale yellow
Wasserlöslichkeit: Soluble in water, methanol, ethanol, dimethyl sulfoxide. Insoluble in ether.
BRN: 1532405 · 1532405
InChI: InChI=1S/C10H13NO4/c12-8-5-6-9(13)11(8)7-3-1-2-4-10(14)15/h5-6H,1-4,7H2,(H,14,15)
InChIKey: WOJKKJKETHYEAC-UHFFFAOYSA-N
SMILES: N1(CCCCCC(O)=O)C(=O)C=CC1=O
CAS Datenbank: 55750 · 55750-53-3(CAS DataBase Reference)
EPA chemische Informationen: 1 H-Pyrrole-1-hexanoic · 1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo- (55750-53-3)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 5 Einträge

Danger

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]；H318 (73.2%): Causes serious eye damage [Danger Serious eye damage/eye irritation]；H319 (25%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (98.2%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 56 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Hazard Classes and CategoriesSkin Irrit. 2 (100%)；Eye Dam. 1 (73.2%)；Eye Irrit. 2 (25%)；STOT SE 3 (98.2%)

Sicherheitsdaten

F: 10-21
wgk: 3
hs_code: 29251900
risk_code: 36/37/38-41-37/38
hazard_code: Xi
safety_code: 26-36-39
Speicherklasse: 11 - Combustible Solids
Hazard Classifications: Skin Irrit. 2STOT SE 3

Chemie und Industrie

Vor- und nachgelagerte Produkte

Vorgelagerte Rohstoffe

Nachgelagerte Produkte

MC-Val-Cit-PAB Mc-Val-Cit-PABC-PNP McMMAE CarbaMic acid, [5-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)pentyl]-, 1,1-diMethylethyl ester 1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo-, 2-[(1,1-diMethylethoxy)carbonyl]hydrazide

Anbieter50 Anbieter

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

上海杰又杰新材料科技有限公司021-64837106 13564410395

T&W GROUP021-61551611 13296011611 · [email protected]

韶远科技（上海）有限公司021-50795510 4000665055 · [email protected]

Ergänzende Hinweise · 1 Eintrag

DefinitionChEBI: 6-Maleimidocaproic acid is a medium-chain fatty acid. It contains a maleimide group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.