StartseiteMCPWorkbenchSkills
StartseiteWorkbenchBenachrichtigungenMein Bereich
Huagongshe Open Project:[email protected]KI-Anbindung: llms.txt · MCP-AnleitungDatenschutz · Nutzungsbedingungen · Supportv1.7.8
  1. Startseite
  2. /Verbindung

DL-4-(2-(Isopropylamino)-1-hydroxyethyl)brenzcatechinhydrochlorid

(+-)-Isoproterenol hydrochloride

HCID 5807
NotizenReaktionen
GrundinformationenÜberblickNamen und BezeichnerEigenschaftenSicherheit und RegulatorischesChemie und IndustrieZugehörige ReaktionenNotizen zur Verbindung
TeilstruktursucheÄhnliche Strukturen suchen

Grundinformationen

CAS
51-30-9
Standard-SMILES
CC(C)NCC(O)c1ccc(O)c(O)c1.Cl
InChIKey
IROWCYIEJAOFOW-UHFFFAOYSA-N
Summenformel
C11H17NO3.ClH
Durchschnittliche Molmasse
247,72 g/mol
Monoisotopische Masse
247,0975211

Überblick

Isoproterenol hydrochloride is an odorless white crystalline powder. Slightly bitter taste. Aqueous solutions turn brownish-pink upon prolonged exposure to air. (NTP, 1992)

Namen und Bezeichner

Bevorzugter Name
(+-)-Isoproterenol hydrochloride
IUPAC
4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol;hydrochloride
Lokaler Name
DL-4-(2-(Isopropylamino)-1-hydroxyethyl)brenzcatechinhydrochlorid
Englischer Name
Isoproterenol hydrochloride
Summenformel
C11H18ClNO3
Molmasse
247.72

Namen und Synonyme

Isoprenaline hydrochloride51-30-9ISOPROTERENOL HYDROCHLORIDEAeroloneAerotrolVapo-IsoIsoproterenol HClAsthpulNorisodrine AerotrolDL-Isoproterenol hydrochloridedl-Isadrine hydrochlorideIsopropylarterenol hydrochloride
Weitere Namen anzeigen
ISOPRENALINE HCLTIMTEC-BB SBB003172dl-isadrinehydrochloridedl-isoprenalinehydrochloride-n-isopropyl-dl-noradrenalineHCl
Isoprenaline chlorideMistarelSuscardiaIsovon(+-)-Isoproterenol hydrochlorideIsoproterenol monohydrochloride(+-)-Isoprenaline hydrochlorideNCI-C55630

Datenbank-Bezeichner

CAS
51-30-9、949-36-0
PubChem CID
5807
DTXSID
DTXSID6025486
ChEMBL
CHEMBL1711

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA)
72,7 Ų
H-Brücken-Donoren
5
H-Brücken-Akzeptoren
4
Frei drehbare Bindungen
4
Schwere Atome
16
Formalladung
0
Komplexität
187

Experimentelle und physikochemische Eigenschaften

Solubility · 2 Einträge

Soluble (NTP, 1992)

>37.2 [ug/mL] (The mean of the results at pH 7.4)

Human Drugs · 2 Einträge

FDA approved drugs -> Active ingredient

FDA approved drugs -> Active ingredient

Melting Point338 to 340 °F (NTP, 1992)
Physical DescriptionIsoproterenol hydrochloride is an odorless white crystalline powder. Slightly bitter taste. Aqueous solutions turn brownish-pink upon prolonged exposure to air. (NTP, 1992)

Physikochemische Eigenschaften

Schmelzpunkt
165 · 165-175 °C (dec.)(lit.)
CAS Datenbank
949 · 949-36-0(CAS DataBase Reference)

Sicherheit und Regulatorisches

Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.

GHS-Klassifizierung

GHS Classification · 4 Einträge

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 41 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Other Safety InformationIMAP assessments - 1,2-Benzenediol, 4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-, hydrochloride: Human health tier I assessment
Fire HazardsFlash point data for this chemical are not available. It is probably combustible. (NTP, 1992)
Health Hazards · 1 Eintrag

SYMPTOMS: Symptoms of exposure to this compound may include tremors, nervous apprehension, palpitations of the heart, epigastric distress, cardiac arrhythmias, myocardial necrosis, cardiac arrest, tachycardia, headache, flushing of the skin, anginal pain, nausea, dizziness, weakness, and sweating. (NTP, 1992)

Reactive GroupAlcohols and Polyols
Reactivity Profile · 1 Eintrag

An acid organic salt. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.

Chemie und Industrie

Pharmakologische Informationen

FDA Pharmacological Classification · 2 Einträge

ISOPROTERENOL HYDROCHLORIDE

Adrenergic beta-Agonists [MoA]; beta-Adrenergic Agonist [EPC]

MeSH Pharmacological Classification · 4 Einträge

Drugs that selectively bind to and activate beta-adrenergic receptors.

Agents that cause an increase in the expansion of a bronchus or bronchial tubes.

Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).

Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.

Anbieter8 Anbieter

武汉易泰科技有限公司上海分公司18930552037 · [email protected]
北京绿百草科技发展有限公司010-61136123 · [email protected]
南京世洲生物科技有限公司13675144456 · [email protected]
Chongqing jooe co., ltd+86-15223382610 · [email protected]
陕西缔都医药化工有限公司029-029-81120477 17792793610 · [email protected]
金锦乐(湖南)化学有限公司18001959627(微信同号) 18001959627 · [email protected]
厦门盈融达化工有限公司+86-0592-6210733 · [email protected]

Zugehörige Reaktionen

5
Reaktionsaufzeichnung erstellen
Reaktionsgleichung von HRID 53100
HRID 53100als Eduktuspto-grants-1997_04
Reaktionsgleichung von HRID 726527
HRID 726527als Eduktuspto-grants-1998_01
Reaktionsgleichung von HRID 1379587
HRID 1379587als Eduktuspto-grants-1997_09
Reaktionsgleichung von HRID 1769224
HRID 1769224als Eduktuspto-grants-1995_01
Reaktionsgleichung von HRID 2256804
HRID 2256804als Eduktuspto-grants-1997_08

Notizen zur Verbindung

Wird geladen…

Auf dieser SeiteGrundinformationenÜberblickNamen und BezeichnerEigenschaftenSicherheit und RegulatorischesChemie und IndustrieZugehörige ReaktionenNotizen zur Verbindung
ChEBI
CHEBI:31453
UNII
DIA2A74855
EC Number
200-089-8、213-438-4
Air and Water ReactionsMay be sensitive to exposure to air and light. (NTP, 1992). Water soluble.
Hazard Classes and CategoriesSkin Irrit. 2 (100%)

Sicherheit und Schutzausrüstung

Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1 Eintrag

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 Eintrag

SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Personal Protective Equipment (PPE) · 1 Eintrag

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

Toxikologische Informationen

Drug Induced Liver Injury · 6 Einträge

Drug Induced Liver Injury Rank (DILIrank 2.0)

Isoproterenol hydrochloride

vNo-DILI-concern

0

No match

DOI:10.1016/j.drudis.2016.02.015

Sicherheitsdaten

F
3-8-10
wgk
2
RTECS-Nr.
DO1925000
risk_code
36/37/38
hazard_code
Xi
safety_code
26-36
Dideu Industries Group Limited
+86-29-81148696 +86-15129568250 · [email protected]