Sematilide
Grundinformationen
- CAS
101526-83-4- Standard-SMILES
CCN(CC)CCNC(=O)c1ccc(NS(C)(=O)=O)cc1- InChIKey
KHYPYQZQJSBPIX-UHFFFAOYSA-N- Summenformel
- C14H23N3O3S
- Durchschnittliche Molmasse
- 313,42 g/mol
- Monoisotopische Masse
- 313,14601278
Überblick
Sematilide is a small molecule drug. The usage of the INN stem '-ilide' in the name indicates that Sematilide is a sematilide derivative class III antiarrhythmic. Sematilide has a monoisotopic molecular weight of 313.15 Da.
Namen und Bezeichner
- Bevorzugter Name
- Sematilide
- IUPAC
- N-[2-(diethylamino)ethyl]-4-(methanesulfonamido)benzamide
- Englischer Name
- N-(DIETHYLAMINOETHYL)-4-METHYLSULFOAMINOBENZAMIDE
- Summenformel
- C14H23N3O3S
- Molmasse
- 313.42
Namen und Synonyme
Sematilide101526-83-4sematilida0NHB13IN3RDTXSID0058720sematilidumRefChem:182337DTXCID3032414Sematilide [INN]N-[2-(diethylamino)ethyl]-4-(methanesulfonamido)benzamideN-(DIETHYLAMINOETHYL)-4-METHYLSULFOAMINOBENZAMIDEN-(2-(Diethylamino)ethyl)-4-(methylsulfonamido)benzamide
Weitere Namen anzeigen
RU-752N-(diethyl-amino-ethyl-)-4-mesyl-amino-benz-amideN-(2-Diethylaminoethyl)-4-(methylsulfonylamino)benzamideBenzamide,N-[2-(diethylamino)ethyl]-4-[(methylsulfonyl)amino]-N-(2-(Diethylamino)ethyl)-4-(methylsulfonamido)benzamide , Sematilide
N-[2-(diethylamino)ethyl]-4-(methanesulfonamido)benzamide;N-[2-(diethylamino)ethyl]-4-(methanesulfonamido)benzamideUNII-0NHB13IN3RSEMATILIDE [MI]SEMATILIDE [WHO-DD]CHEMBL95804SCHEMBL161098orb1708551BDBM50228547
Datenbank-Bezeichner
- CAS
101526-83-4
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 0,5
- Polarare Oberfläche (TPSA)
- 86,9 Ų
- H-Brücken-Donoren
- 2
- H-Brücken-Akzeptoren
- 5
- Frei drehbare Bindungen
- 8
- Schwere Atome
- 21
- Formalladung
- 0
- Komplexität
- 408
Experimentelle und physikochemische Eigenschaften
LogP1.36
Physikochemische Eigenschaften
- Dichte
- 1.205 · 1.205±0.06 g/cm3(Predicted)
- pka
- 7.43 · 7.43±0.10(Predicted)
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
Anwendungen
VerwendenCardiac depressant (anti-arrhythmic).
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