Cytidin-5'-(dinatriumdihydrogentriphosphat)

Cytidine triphosphate disodium salt

HCID 593CAS 36051-68-0

Grundinformationen

Standard-SMILES
Nc1ccn(C2OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C2O)c(=O)n1
InChIKey
PCDQPRRSZKQHHS-UHFFFAOYSA-N
Summenformel
C9H16N3O14P3
Durchschnittliche Molmasse
483,16 g/mol
Monoisotopische Masse
482,98451208

Namen und Bezeichner

Bevorzugter Name
Cytidine triphosphate disodium salt
IUPAC
[[5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Lokaler Name
Cytidin-5'-(dinatriumdihydrogentriphosphat)
Englischer Name
Cytidine 5'-triphosphate disodium salt
Summenformel
C9H17N3NaO14P3
Molmasse
507.15

Namen und Synonyme

Ara-C triphosphateCytidine triphosphate disodium saltSCHEMBL15958751DTXSID20861610NSC20261[[5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphateNS00041321L0010914-Amino-1-[5-O-(hydroxy{[hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl)pentofuranosyl]pyrimidin-2(1H)-oneCTP DISODIUM SALTCTP.2NadTTP.Na2
Weitere Namen anzeigen
5′-CTP,2CTPNa.2H2OCTP, NA2H25′-CTP,2Na5'-CMP 2NA5'-CTP-Na2CTP –, Solid (1 g)

Datenbank-Bezeichner

CAS
36051-68-0
PubChem CID
593
DTXSID
DTXSID20861610

Eigenschaften

Berechnete Struktureigenschaften

XLogP
-5,6
Polarare Oberfläche (TPSA)
268 Ų
H-Brücken-Donoren
7
H-Brücken-Akzeptoren
14
Frei drehbare Bindungen
8
Schwere Atome
29

Physikochemische Eigenschaften

Flammpunkt
113 °C · 113 °C
storage temp.
-20 °C · -20°C
Löslichkeit
2 O: · H2O: 50 mg/mL, clear, colorless
Aggregatzustand
Powder
Farbe
White
Wasserlöslichkeit
Soluble in water. Insoluble in ethanol, chloroform and ether.

Sicherheit und Regulatorisches

Sicherheitsdaten

F
10-21
wgk
3
hs_code
29349990
safety_code
24/25
Speicherklasse
11 - Combustible Solids

Chemie und Industrie

Anwendungen · 1 Eintrag

VerwendenCytidine 5'-triphosphate disodium salt is a pyrimidine nucleoside triphosphate salt that is involved in a variety of biochemical reactions. It is used in the synthesis of RNA by RNA polymerases. In the formation of phosphatidylcholine (PC), CTP reacts with phosphocholine, via CTP:phosphocholine cytidylyltransferases, to produce CDP-choline and diphosphate. This is the rate-limiting step in PC synthesis and, as a pivotal step in cell proliferation, can be important in cancer. CTP also interacts with N-acylneuraminate, in a reaction mediated by N-acylneuraminate cytidylyltransferase, to generate an intermediate that is required for sialylation, namely CMP-N-acylneuraminic acid.[Cayman Chemical]

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