Grundinformationen
- Standard-SMILES
Cl.N#Cc1ccc(C2CCCc3cncn32)cc1- InChIKey
UKCVAQGKEOJTSR-UHFFFAOYSA-N- Summenformel
- C14H14ClN3
- Durchschnittliche Molmasse
- 259,73 g/mol
- Monoisotopische Masse
- 259,08762513
Überblick
Fadrozole hydrochloride is an imidazopyridine.
Namen und Bezeichner
- Bevorzugter Name
- Benzonitrile, 4-(5,6,7,8-tetrahydroimidazo(1,5-a)pyridin-5-yl)-, hydrochloride (1:1)
- IUPAC
- 4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile;hydrochloride
Namen und Synonyme
FADROZOLE HYDROCHLORIDE102676-31-3Fadrozole HClAfema4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile hydrochlorideBenzonitrile, 4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)-, hydrochloride (1:1)ArensinFadrozole monohydrochlorideH0Q44H4ECQ4-(5,6,7,8-Tetrahydroimidazo(1,5-a)pyridin-5-yl)benzonitrile HydrochlorideBenzonitrile, 4-(5,6,7,8-tetrahydroimidazo(1,5-a)pyridin-5-yl)-, hydrochloride (1:1)Hydrochloride, Fadrozole
Weitere Namen anzeigen
RefChem:597145Monohydrochloride, Fadrozole631-311-5CGS 16949AFadrozole.HClFadrozole hydrochloride [USAN]DTXSID4020618Fadrozole (hydrochloride)
Datenbank-Bezeichner
- CAS
102676-31-3- PubChem CID
- 59694
- DTXSID
DTXSID4020618- ChEMBL
CHEMBL468419- ChEBI
CHEBI:31589- UNII
- H0Q44H4ECQ
- EC Number
- 631-311-5
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 41,6 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 2
- Frei drehbare Bindungen
- 1
- Schwere Atome
- 18
- Formalladung
- 0
- Komplexität
- 311
Sicherheit und Regulatorisches
GHS-Klassifizierung
GHS Classification
Danger
H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]
P203, P264, P270, P280, P301+P316, P318, P321, P330, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Hazard Classes and CategoriesAcute Tox. 3 (100%)
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
Compounds which inhibit or antagonize the action or biosynthesis of estrogenic compounds.
Antineoplastic agents that are used to treat hormone-sensitive tumors. Hormone-sensitive tumors may be hormone-dependent, hormone-responsive, or both. A hormone-dependent tumor regresses on removal of the hormonal stimulus, by surgery or pharmacological block. Hormone-responsive tumors may regress when pharmacologic amounts of hormones are administered regardless of whether previous signs of hormone sensitivity were observed. The major hormone-responsive cancers include carcinomas of the breast, prostate, and endometrium; lymphomas; and certain leukemias. (From AMA Drug Evaluations Annual 1994, p2079)
Compounds that inhibit AROMATASE in order to reduce production of estrogenic steroid hormones.
Zugehörige Reaktionen
15
Verknüpfte Notizen
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