HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Dexpramipexole
DexpraMipexole · (R)-N6-Propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine · Pramipexole-2 · R-(+)-Pramipexole · (R)-Pramipexole 2HCl · Dexpramipexole impurity · Pramipexcole EP impurity D · (R)-PRAMIPEXOLE
Identifikatoren & physikalische Daten
| CAS No. | 104632-28-2 |
|---|---|
| Summenformel | C10H17N3S |
| Durchschnittliche Molmasse | 211,33 g/mol |
| Monoisotopische Masse | 211,11431854 g/mol |
| SMILES | CCCN[C@@H]1CCc2nc(N)sc2C1 |
| InChIKey | FASDKYOPVNHBLU-SSDOTTSWSA-N |
| PubChem CID | 59868 |
| ChEMBL | CHEMBL249420 |
| ChEBI | CHEBI:232420 |
| EC No. | 110-340-2 |
| DTXSID | DTXSID50146624 |
Chemische & physikalische Eigenschaften
| XLogP | 1,9 |
|---|---|
| Polarare Oberfläche (TPSA) | 79,2 |
| H-Brücken-Donoren | 2 |
| H-Brücken-Akzeptoren | 4 |
| Frei drehbare Bindungen | 3 |
| Schwere Atome | 14 |
| Formalladung | 0 |
| Komplexität | 188 |
| Schmelzpunkt | 270-272°C |
| Siedepunkt | 378.0±42.0 °C(Predicted) |
| Dichte | 1.17±0.1 g/cm3 (20 ºC 760 Torr) |
| Lagerbedingungen | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| Löslichkeit | DMSO (Slightly), Methanol (Sparingly, Sonicated), Water (Slightly) |
| pKa (Säurekonstante) | 9.47±0.20(Predicted) |
| Aggregatzustand | Solid |
| Farbe | White to Pale Yellow |
| InChI | InChI=1S/C10H17N3S/c1-2-4-13-5-3-7-8(6-13)10(12)14-9(7)11/h2-6,11-12H2,1H3 |
| InChIKey | RUDWASKCQMKNHV-UHFFFAOYSA-N |
| SMILES | C1(N)=C2CN(CCC)CCC2=C(N)S1 |
| CAS Datenbank | 104632-28-2 |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory. |
|---|---|
| Hazard Classes and Categories | Acute Tox. 4 (100%) |
Anwendungen & Verwendung
Verwenden
(R)-Pramipexole enantiomer. A dopamine-D2-receptor agonist. Antiparkinsonian