HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Bromo-4-pyridinol
3-Bromopyridin-4-ol · 3-BROMO-4-PYRIDINOL · 4-Pyridinol, 3-bromo- · 3-bromo-1H-pyridin-4-one · 3-BROMO-4-HYDROXYPYRIDINE · 4-HYDROXY-3-BROMOPYRIDINE · 3-Bromo-4-hydroxypyridine,97% · 3-BROMO-4-HYDROXYPYRIDINE 97%
Identifikatoren & physikalische Daten
| CAS No. | 36953-41-0 |
|---|---|
| Summenformel | C5H4BrNO |
| Durchschnittliche Molmasse | 174 g/mol |
| Monoisotopische Masse | 172,94763 g/mol |
| SMILES | O=c1cc[nH]cc1Br |
| InChIKey | JWHZKNRXTDYNJO-UHFFFAOYSA-N |
| PubChem CID | 599549 |
| EC No. | 670-507-5 |
| DTXSID | DTXSID40344798 |
Chemische & physikalische Eigenschaften
| XLogP | 1 |
|---|---|
| Polarare Oberfläche (TPSA) | 29,1 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 8 |
| Formalladung | 0 |
| Komplexität | 171 |
| Schmelzpunkt | 225-230℃ |
| Siedepunkt | 338.2±22.0 °C(Predicted) |
| Dichte | 1.788±0.06 g/cm3(Predicted) |
| Lagerbedingungen | Inert atmosphere,Room Temperature |
| Aggregatzustand | powder |
| pKa (Säurekonstante) | 3.71±0.18(Predicted) |
| Farbe | light yellow |
| CAS Datenbank | 36953-41-0(CAS DataBase Reference) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 6 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Hazard Classes and Categories | Skin Irrit. 2 (100%) |
| Zollcode | 2933399990 |
Anwendungen & Verwendung
Verwenden
3-Bromo-4-hydroxypyridine is a pyrrole that can be used in cancer treatment. It inhibits the growth of cancer cells by binding to MKN-45 on the cell surface, thereby preventing it from binding to other proteins and triggering cell proliferation.