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HCID 6029Erstellt: 26. Oktober 2026

Uridine

Uridine · 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione · UR · URACIL RIBOSIDE · URD · Uridin · beta-Uridine · URACIL-1-BETA-D-RIBOFURANOSIDE

https://huagongshe.com/de/chemical/6029

Molekülstruktur von Uridine

Identifikatoren & physikalische Daten

CAS No.58-96-8
SummenformelC9H12N2O6
Durchschnittliche Molmasse244,2 g/mol
Monoisotopische Masse244,0695361 g/mol
SMILESO=c1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1
InChIKeyDRTQHJPVMGBUCF-XVFCMESISA-N
PubChem CID6029
ChEMBLCHEMBL100259
ChEBICHEBI:16704
EC No.200-407-5
DTXSIDDTXSID40891555

Chemische & physikalische Eigenschaften

XLogP-2
Polarare Oberfläche (TPSA)119
H-Brücken-Donoren4
H-Brücken-Akzeptoren6
Frei drehbare Bindungen2
Schwere Atome17
Formalladung0
Komplexität370
StoffklassenBiological Agents -> Nucleic Acids and Derivatives
ArzneimittelPharmaceuticals -> Listed in ZINC15
SpringerMaterials PropertiesCrystal structure
LogP (Verteilungskoeffizient)-1.98
Löslichkeit34.9 [ug/mL] (The mean of the results at pH 7.4)H2O: 50 mg/mLSoluble in water, dimethylsulfoxide, and methanol.
Schmelzpunkt163 °C163-167 °C(lit.)
Optical Rotation(c = 2, H2O) [a]20 D = 9.4 ± 2°
Physical DescriptionSolid[Merck Index] White powder[Alfa Aesar MSDS]
Collision Cross Section160.1 Ų [M+Na]+ [CCS Type: DTMethod: single field calibrated with Agilent tune mix (Agilent)]152 Ų [M+H]+ [CCS Type: TWMethod: calibrated with polyalanine]150.7 Ų [M-H]- [CCS Type: DTMethod: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]166 Ų [M+Na]+ [CCS Type: DTMethod: stepped-field]152 Ų [M-H]-
Siedepunkt387.12°C (rough estimate)
Dichte1.4221 (rough estimate)
Brechungsindex9 ° (C=2, H2O)
Lagerbedingungen2-8°C
Aggregatzustandpowder
pKa (Säurekonstante)9.39±0.10(Predicted)
FarbeWhite to almost white
pH9.05
Biologische Quellesynthetic (organic)
Merck14,9877
BRN754904
Kosmetik-Inhaltsstoffe FunktionenSKIN PROTECTINGSKIN CONDITIONING
InChI1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
InChIKeyDRTQHJPVMGBUCF-XVFCMESISA-N
SMILESOC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O
LogP (Verteilungskoeffizient)-1.581 (est)
CAS Datenbank58-96-8(CAS DataBase Reference)
NIST chemische InformationenUridine(58-96-8)
EPA chemische InformationenUridine (58-96-8)

Sicherheit & Vorschriften

GHS-EinstufungThis chemical does not meet GHS hazard criteria for 85.7% (12 of 14) of all reports.WarningH315 (14.3%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 14 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Regulatorische InformationenChemical: UridineStatus: Active Update: 12-10-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/31621Uridine: Does not have an individual approval but may be used under an appropriate group standard
Weitere SicherheitsinformationenEvaluation - Chemicals that are unlikely to require further regulation to manage risks to environment
GefahrenübersichtCauses somnolence, other liver changes, effects on transaminases, and inflammation in acute intraperitoneal studies of mice and rats[RTECS] May cause irritation[Alfa Aesar MSDS]
Hazard Classes and CategoriesSkin Irrit. 2 (14.3%)
Toxicity DataMouse(ip): LD50 4335 mg/kg
F10
Wassergefährdungsklasse (WGK)3
TSCA-Inventar-StatusTSCA listed
Zollcode29335990
RTECS-Nr.YR1450000
R-Sätze (R)36/37/38
GefahrensymboleXi
hazard_noteKeep Cold
Sicherheitshinweise (S)24/25-36-26
Lagerklasse11 - Combustible Solids

Anwendungen & Verwendung

Verwenden

Uridine is a nucleoside, contains a uracil attached to a ribose ring via a β-N1-glycosidic bond