Fananserin
Grundinformationen
- CAS
127625-29-0- Standard-SMILES
O=S1(=O)c2cccc3cccc(c23)N1CCCN1CCN(c2ccc(F)cc2)CC1- InChIKey
VGIGHGMPMUCLIQ-UHFFFAOYSA-N- Summenformel
- C23H24FN3O2S
- Durchschnittliche Molmasse
- 425,5 g/mol
- Monoisotopische Masse
- 425,15732635
Namen und Bezeichner
- Bevorzugter Name
- Fananserin
- IUPAC
- 3-[3-[4-(4-fluorophenyl)piperazin-1-yl]propyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide
- Englischer Name
- Fananserin
- Summenformel
- C23H24FN3O2S
- Molmasse
- 425.52
Namen und Synonyme
Fananserin127625-29-0RP 62203RP-62203FANANSERINEFananserinaDTXSID8046743RP6220338QJ762ET6DTXCID60267433-[3-[4-(4-fluorophenyl)piperazin-1-yl]propyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxidefananserinum
Weitere Namen anzeigen
Fananserin, 10 mM in DMSO2-[3-[4-(4-Fluorophenyl)piperazino]propyl]-2H-naphth[1,8-cd]isothiazole 1,1-dioxide2-[3-[4-(4-Fluorophenyl)-1-piperazinyl]propyl]-2H-naphthyl[1,8-cd]isothiazole-1,1-dioxideFananserin,Inhibitor,5-HT Receptor,inhibit,5-HT2,RP62203,RP-62203,dopamine,Dopamine Receptor,Serotonin Receptor,5-hydroxytryptamine Receptor
3-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)-2$l^(6)-thia-3-azatricyclo(6.3.1.0^(4,12))dodeca-1(11),4(12),5,7,9-pentaene-2,2-dione3-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)-2lambda6-thia-3-azatricyclo(6.3.1.04,12)dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide3-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}-2$l^{6}-thia-3-azatricyclo[6.3.1.0^{4,12}]dodeca-1(11),4(12),5,7,9-pentaene-2,2-dione2-(3-(4-(4-fluorophenyl)-1-piperazinyl)propyl)-2H-naphth(1,8-cd)isothiazole 1,1-dioxideRefChem:9214632H-Naphth[1,8-cd]isothiazole, 2-[3-[4-(4-fluorophenyl)-1-piperazinyl]propyl]-, 1,1-dioxideCHEMBL838942-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide
Datenbank-Bezeichner
- CAS
127625-29-0- PubChem CID
- 60785
- DTXSID
DTXSID8046743- ChEMBL
CHEMBL83894- ChEBI
CHEBI:92159- UNII
- 38QJ762ET6
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 4
- Polarare Oberfläche (TPSA)
- 52,2 Ų
- H-Brücken-Donoren
- 0
- H-Brücken-Akzeptoren
- 6
- Frei drehbare Bindungen
- 5
- Schwere Atome
- 30
- Formalladung
- 0
- Komplexität
- 683
Physikochemische Eigenschaften
- Schmelzpunkt
- 95 · 95-97 °C(Solv: acetonitrile (75-05-8))
- Siedepunkt
- 641.1 · 641.1±65.0 °C(Predicted)
- Dichte
- 1.331 · 1.331±0.06 g/cm3(Predicted)
- storage temp.
- Store at RT
- Löslichkeit
- 100 mM · Soluble to 100 mM in DMSO
- Aggregatzustand
- Powder
- pka
- 7.31 · 7.31±0.10(Predicted)
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
Sicherheitsdaten
- Alarmwort
- Warnung
- Gefahrenhinweise
- Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code H315
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or SEROTONIN RECEPTOR AGONISTS.
Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus.
Drugs that bind to and activate dopamine receptors.
Anwendungen
VerwendenFananserin is an antagonist of 5-HT2A.
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