Trisodium phosphate dodecahydrate
TSP · SODIUM PHOSPHATE TRIBASIC · SODIUM PHOSPHATE DODECAHYDRATE · TRI-SODIUM PHOSPHATE DODECAHYDRATE · sodiuM phosphat · TRI-SODIUM ORTHOPHOSPHATE DODECAHYDRATE · KH2PO9 · TSP, 12-HYDRATE
Identifikatoren & physikalische Daten
| CAS No. | 10101-89-0 |
|---|---|
| Summenformel | H24Na3O16P |
| Durchschnittliche Molmasse | 380,12 g/mol |
| Monoisotopische Masse | 380,04950452 g/mol |
| SMILES | O.O.O.O.O.O.O.O.O.O.O.O.O=P([O-])([O-])[O-].[Na+].[Na+].[Na+] |
| InChIKey | ASTWEMOBIXQPPV-UHFFFAOYSA-K |
| PubChem CID | 61473 |
| EC No. | 600-151-8 |
| DTXSID | DTXSID0049810 |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 98,3 |
|---|---|
| H-Brücken-Donoren | 12 |
| H-Brücken-Akzeptoren | 16 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 20 |
| Formalladung | 0 |
| Komplexität | 36 |
| Schmelzpunkt | Melting point equals 164 to 170 ° F75 °C |
| Physical Description | LiquidDry PowderColorless to white crystals[CAMEO] |
| Dichte | 1.62 g/mL at 25 °C |
| Lagerbedingungen | Store at +5°C to +30°C. |
| Löslichkeit | H2O: 0.5 M at 20 °C, clear, colorless258 g/L (20 ºC) |
| Aggregatzustand | Solid |
| Wichte | 1.62 |
| Farbe | White |
| pH | 12 (10g/l, H2O, 20℃) |
| Merck | 14,8662 |
| Stabilität | Stable. Incompatible with strong acids. Keep dry. |
| InChI | 1S/3Na.H3O4P.12H2O/c1-5(2,3)4/h(H3,1,2,3,4)12*1H2/q3*+1/p-3 |
| InChIKey | ASTWEMOBIXQPPV-UHFFFAOYSA-K |
| SMILES | O.O.O.O.O.O.O.O.O.O.O.O.[Na+].[Na+].[Na+].[O-]P([O-])([O-])=O |
| LogP (Verteilungskoeffizient) | -2.148 (est) |
| CAS Datenbank | 10101-89-0(CAS DataBase Reference) |
| EPA chemische Informationen | Trisodium phosphate dodecahydrate (10101-89-0) |
| Absorption | ≤0.023 at 280 in H2O at 0.5M≤0.035 at 260 in H2O at 0.5M |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 1.3% (6 of 472) of reports.DangerH314 (20.8%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]H315 (74.6%): Causes skin irritation [Warning Skin corrosion/irritation]H319 (77.8%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H335 (44.9%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]P260, P261, P264, P264+P265, P271, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P319, P321, P332+P317, P337+P317, P362+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 472 reports by companies from 17 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Reported as not meeting GHS hazard criteria per 6 of 472 reports by companies.There are 16 notifications provided by 466 of 472 reports by companies with hazard statement code(s).Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| Regulatorische Informationen | Chemical: Phosphoric acid, trisodium salt, dodecahydratePhosphoric acid, trisodium salt, dodecahydrate is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Phosphoric acid, trisodium salt, dodecahydrate are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Trisodium phosphate: Does not have an individual approval but may be used under an appropriate group standard |
| Weitere Sicherheitsinformationen | IMAP assessments - Trisodium phosphate: Human health tier II assessmentIMAP assessments - Phosphoric acid, trisodium salt, dodecahydrate: Environment tier I assessment |
| Gefahrenübersicht | Can cause burns to the eyes and skinHarmful if ingested[CAMEO] Aqueous solutions are highly alkaline[HSDB] Dusts and solutions > 0.1% are corrosive to the eyes and possibly to the skin[CHEMINFO] |
| Hazard Classes and Categories | Skin Corr. 1C (20.8%)Skin Irrit. 2 (74.6%)Eye Irrit. 2 (77.8%)STOT SE 3 (44.9%)Skin corrosion - category 1B |
| Unerwünschte Wirkungen | Dermatotoxin - Skin burns. |
| Wassergefährdungsklasse (WGK) | 1 |
| TSCA-Inventar-Status | Yes |
| UN-Transportnummer | UN 3262 8/PG 3 |
| Zollcode | 28352300 |
| RTECS-Nr. | TC9575000 |
| R-Sätze (R) | 34-35-36/38 |
| Toxizität | LD50 orally in Rabbit: 7400 mg/kg |
| Gefahrensymbole | C |
| Sicherheitshinweise (S) | 26-36/37/39-45-24/25 |
| Gefahrenklasse | 8Eye Irrit. 2Skin Irrit. 2STOT SE 3 |
| Verpackungsgruppe | III |
| Lagerklasse | 8A - Combustible corrosive hazardous materials |
Anwendungen & Verwendung
Beschreibung
Sodium phosphate tribasic dodecahydrate is also known as trisodium phospate or TSP. It is a highly soluble in water and widely used as a cleaning agent. The pH of a 1% solution is typically around 12, making this reagent sufficiently alkaline for saponification of grease and oils. In combination with surfactants, TSP is an excellent agent for cleaning everything from laundry to concrete driveways. This versatility and low manufacturing price made TSP the basis for a plethora of cleaning products sold in the mid-20th century. Trisodium phosphate is used in the isolation of mycobacteria, including culturing of tubercle bacilli. Has been used as a protein precipitant in certain applications and in co-precipitation and fractionization of nucleotides. May be used for the preservation of biologically active soil samples. Because of the alkaline pH, TSP disrupts cytoplasmic and outer membranes of Salmonella enterica cells making it useful in preventing the spread of bacteria. It is used in photographic developing, clarifying sugar, removing boiler scale, softening water and manufacturing of paper. They are added to many foods as an emulsifier to prevent oil separation. It can be utilized as a leavening agent. Some instances of these foods include the batter coating on breaded fish or chicken, and commercially baked cakes. Adding this item to food increases the shelf life of the food, maintaining the texture and visual aspect of the food.
Verwenden
Sodium phosphate tribasic dodecahydrate is often used in the formulation of various buffers.