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Sodium Thiosulfate Pentahydrate

HCID 61475
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Grundinformationen

CAS
10102-17-7
Standard-SMILES
O.O.O.O.O.O=S([O-])([O-])=S.[Na+].[Na+]
InChIKey
PODWXQQNRWNDGD-UHFFFAOYSA-L
Summenformel
H10Na2O8S2
Durchschnittliche Molmasse
248,19 g/mol
Monoisotopische Masse
247,96124818

Überblick

Sodium thiosulfate pentahydrate is a hydrate consisting of sodium thiosulfate with 5 mol eq. of water. It has a role as a nephroprotective agent, an antifungal drug and an antidote to cyanide poisoning. It contains a sodium thiosulfate.

Namen und Bezeichner

Bevorzugter Name
Sodium Thiosulfate Pentahydrate
IUPAC
disodium;dioxido-oxo-sulfanylidene-λ6-sulfane;pentahydrate
Englischer Name
Sodium thiosulfate pentahydrate
Summenformel
H10Na2O8S2
Molmasse
248.18

Namen und Synonyme

SODIUM THIOSULFATE PENTAHYDRATE10102-17-7Disodium thiosulfate pentahydrateAntichlorSodium thiosulfate, pentahydrateThiosulfuric acid (H2S2O3), disodium salt, pentahydrateDTXSID6044197CHEBI:32150pentahydrate of sodium thiosulfateRefChem:931939DTXCID4024197600-156-5
Weitere Namen anzeigen
SODIUM THIOSULPHATESODIUM THIOSULFATE SOLUTION1kgHYPOSodium Thiosulfate Hydrate4-MPHSodiuM thiosulfate pentahydra5-BPDiNatriumthiosulfat
Tinversodium thiosulphate pentahydrateNa2S2O3.5H2OSodium Hyposulfite PentahydrateMFCD00149186disodium;dioxido-oxo-sulfanylidene-lambda6-sulfane;pentahydrateThiosulfuric acid (H2S2O3), sodium salt, hydrate (1:2:5)Sodium thiosulfate (pentahydrate)

Datenbank-Bezeichner

CAS

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA)
109 Ų
H-Brücken-Donoren
5
H-Brücken-Akzeptoren
9
Frei drehbare Bindungen
0
Schwere Atome
12
Formalladung
0
Komplexität
82,6

Experimentelle und physikochemische Eigenschaften

Chemical ClassesOther Classes -> Sulfur Compounds
Density1.69 @25 °C
Melting Point48 °C
Physical Description · 2 Einträge

Large Crystals; Dry Powder; Other Solid

Odorless solid; Deliquesces slightly in moist air; [Merck Index] Colorless odorless crystalline solid; [Sigma-Aldrich MSDS]

Physikochemische Eigenschaften

Schmelzpunkt
48.5 °C · 48.5 °C
Siedepunkt
100 C · 100 C
Dichte
1.01 g/mL · 1.01 g/mL at 25 °C
Brechungsindex
1.489 · 1.489
storage temp.
5 °C · Store at +5°C to +30°C.
Löslichkeit
2 O: · H2O: 1 M at 20 °C, clear, colorless
Aggregatzustand
Solid
Farbe
White tranparent

Sicherheit und Regulatorisches

Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.

GHS-Klassifizierung

GHS Classification · 3 Einträge

This chemical does not meet GHS hazard criteria for 98.6% (277 of 281) of all reports.

Not Classified

Aggregated GHS information provided per 281 reports by companies from 6 notifications to the ECHA C&L Inventory.

Gefahrenhinweise

Regulatory Information · 3 Einträge

Chemical: Thiosulfuric acid (H2S2O3), disodium salt, pentahydrate

Thiosulfuric acid (H2S2O3), disodium salt, pentahydrate is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Thiosulfuric acid (H2S2O3), disodium salt, pentahydrate are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Sodium thiosulfate pentahydrate: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Thiosulfuric acid (H2S2O3), disodium salt, pentahydrate: Human health tier I assessment
Hazards Summary · 1 Eintrag

Causes convulsions, ataxia, and lung changes in intravenous lethal-dose studies of mice; Causes increased pulse rate and respiratory stimulation in intravenous lethal-dose studies of dogs; [RTECS] Not considered hazardous by GHS classification; [Sigma-Aldrich MSDS] See Sodium thiosulfate.

EPA Safer ChemicalChemical: Sodium thiosulfate, pentahydrate
Hazard Classes and CategoriesNot Classified

Sicherheit und Schutzausrüstung

Chemie und Industrie

Pharmakologische Informationen

MeSH Pharmacological Classification · 4 Einträge

Agents counteracting or neutralizing the action of POISONS.

Naturally occurring or synthetic substances that inhibit or retard oxidation reactions. They counteract the damaging effects of oxidation in animal tissues.

Drugs used in the treatment of tuberculosis. They are divided into two main classes: first-line agents, those with the greatest efficacy and acceptable degrees of toxicity used successfully in the great majority of cases; and second-line drugs used in drug-resistant cases or those in which some other patient-related condition has compromised the effectiveness of primary therapy.

Chemicals that bind to and remove ions from solutions. Many chelating agents function through the formation of COORDINATION COMPLEXES with METALS.

Verwendung und Herstellung

Uses · 2 Einträge

Used to remove chlorine from solutions; to bleach paper, bone, straw, and ivory; as a fixer in photography; to extract silver from ores; as mordant in dyeing and printing textiles; in leather manufacturing; in pharmaceutical production (antioxidant), and as an antidote for cyanide poisoning; [Merck Index] Permitted for use as an inert ingredient in non-food pesticide products; [EPA]

Pulp and Paper Processing [Category: Industry]

U.S. Production2023: 4,000,000 - <5,500,000 lb
Consumer UsesNot Known or Reasonably Ascertainable
Industry UsesLaboratory chemicals
Use Classification · 2 Einträge

EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives

Safer Chemical Classes -> Green half-circle - The chemical is expected to be of low concern

General Manufacturing InformationTextiles, apparel, and leather manufacturing

Zugehörige Reaktionen

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Reaktionsgleichung von HRID 20516
HRID 20516als Eduktuspto-grants-2010_06
Reaktionsgleichung von HRID 20524
HRID 20524als Eduktuspto-grants-2010_06
Reaktionsgleichung von HRID 22643
HRID 22643als Eduktuspto-grants-2005_02
Reaktionsgleichung von HRID 32011
HRID 32011als Eduktuspto-grants-2008_09
Reaktionsgleichung von HRID 32016
HRID 32016als Eduktuspto-grants-2008_09
Reaktionsgleichung von HRID 32019
HRID 32019als Eduktuspto-grants-2008_09
Reaktionsgleichung von HRID 32021
HRID 32021als Eduktuspto-grants-2008_09
Reaktionsgleichung von HRID 47342
HRID 47342als Eduktuspto-grants-2004_03
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Weitere Aktionen
Neue NotizNeue ReaktionAnfrage stellen
10102-17-7
PubChem CID
61475
DTXSID
DTXSID6044197
ChEMBL
CHEMBL2096650
ChEBI
CHEBI:32150
UNII
HX1032V43M
EC Number
600-156-5
Wichte
1.729 · 1.729
Geruch (Odor)
Odorless
PH
6 · 6.0-7.5 (100g/l, H2O, 20℃)
Wasserlöslichkeit
680 g/L · 680 g/L (20 ºC)
Merck
14 · 14,8694
Stabilität
Stable. Incompatible with strong acids, iodine, mercury.
Kosmetik-Inhaltsstoffe Funktionen
REDUCING
InChI
1S/2Na.H2O3S2.5H2O/c;;1-5(2,3)4;;;;;/h;;(H2,1,2,3,4);5*1H2/q2*+1;;;;;;/p-2
InChIKey
AKHNMLFCWUSKQB-UHFFFAOYSA-L
SMILES
O.O.O.O.O.[Na+].[Na+].[O-]S([O-])(=O)=S
LogP
-0.428 · -0.428 (est)
CAS Datenbank
10102 · 10102-17-7(CAS DataBase Reference)
EPA chemische Informationen
Thiosulfuric acid (H2S2O3), disodium salt, pentahydrate (10102-17-7)
Protective Action Criteria (PAC) · 3 Einträge

4.9 [mg/m3]

54 [mg/m3]

320 [mg/m3]

Sicherheitsdaten

F
10
wgk
1
tsca
Yes
hs_code
28323000
RTECS-Nr.
WE6660000
risk_code
36/37/38
Toxizität
LD50 orally in Rabbit: > 5000 mg/kg
hazard_code
Xi
safety_code
24/25-37/39-36-26
Speicherklasse
11 - Combustible Solids
Anwendungen · 1 Eintrag

VerwendenSodium thiosulfate pentahydrate is used as an analytical reagent in laboratories. It is used in photographic processing and in gold extraction. Its alkylated derivatives, S-alkylthiosulfonates, are known as Bunte salts. It is involved in the preparation of thioglycolic acid. Furthermore, it is used to dechlorinate tap water, for removing free bromine from solutions and to check the pH of bleach solutions with liquid indicators. Other uses include tanning of leather; as an active component in hand warmers and chemical heating pads and as an anionic surfactant to aid in the dispersion of pharmaceutical preparations.

Vor- und nachgelagerte Produkte

Vorgelagerte Rohstoffe

ZinkSchwefelCalciumoxidDinatriumsulfidNatriumsulfitSchwefeldioxidPhenol, 2,4-Dinitro-, sulfuriertIndustrial nitric acidKaliumnatriumtartratVanadiumpentoxidHydrogenchloridSulphurNatriumhydroxidBariumsulfidHolzkohle, aktiviertSchwefelsureNatriumcarbonat

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