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Ammonium Laureth Sulfate

HCID 61913
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Grundinformationen

CAS
32612-48-9
Standard-SMILES
CCCCCCCCCCCCOCCOS(=O)(=O)O.N
InChIKey
OPVLOHUACNWTQT-UHFFFAOYSA-N
Summenformel
C14H33NO5S
Durchschnittliche Molmasse
327,48 g/mol
Monoisotopische Masse
327,20794433

Überblick

Ammonium laureth sulfate is a surfactant often found in shampoos. It can be mildly irritating. (L1888)

Namen und Bezeichner

Bevorzugter Name
Ammonium Laureth Sulfate
IUPAC
azane;2-dodecoxyethyl hydrogen sulfate
Englischer Name
Ammonium Laureth Sulfate
Summenformel
(C2H4O)nC12H26O4S.H3N
Molmasse
328.37638

Namen und Synonyme

(2-(dodecyloxy)ethoxy)sulfonic acid amine32612-48-943ZIH89I489C50N72CDB9LPV636QCVAmmonium Laureth SulfateE1ZP93931SPEG-(1-4) Lauryl ether sulfate, ammonium saltPEG-12 Lauryl ether sulfate, ammonium saltPEG-5 Lauryl ether sulfate, ammonium saltPEG-7 Lauryl ether sulfate, ammonium saltPEG-9 Lauryl ether sulfate, ammonium salt
Weitere Namen anzeigen
alesDP-70POE(1)C12H26Na2O5SAMMONIUMLAURETHSULPHATEAMMONIUM LAURETH-9 SULFATEAMMONIUM LAURETH-7 SULFATEAMMONIUM LAURETH-5 SULFATE
RefChem:1076669Ammonium lauryl ether sulfateazane;2-dodecoxyethyl hydrogen sulfateSCHEMBL675554

Datenbank-Bezeichner

CAS
32612-48-9
PubChem CID
61913
EC Number
608-760-0、681-645-0

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA)
82,2 Ų
H-Brücken-Donoren
2
H-Brücken-Akzeptoren
6
Frei drehbare Bindungen
15
Schwere Atome
21
Formalladung
0
Komplexität
284

Experimentelle und physikochemische Eigenschaften

PolymersOther Classes -> Polyoxyethylenes
Cosmetics · 2 Einträge

Cosmetic ingredients (Ammonium Laureth Sulfate) -> CIR (Cosmetic Ingredient Review)

Foaming; Surfactant; Cleansing

Food Contact Substances · 2 Einträge

FCS -> FDA Cumulative Estimated Daily Intake (CEDI)

FCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR

Physical DescriptionLight yellow viscous liquid; [MSDSonline]

Physikochemische Eigenschaften

Kosmetik-Inhaltsstoffe Funktionen
CLEANSINGSURFACTANT - CLEANSINGFOAMING
LogP
5.405 · 5.405 (est)
CAS Datenbank
32612 · 32612-48-9
EPA chemische Informationen
Polyethylene glycol lauryl ether sulfate ammonium salt (32612-48-9)

Sicherheit und Regulatorisches

Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.

GHS-Klassifizierung

GHS Classification · 6 Einträge

This chemical does not meet GHS hazard criteria for 12.6% (59 of 469) of reports.

Danger

H315 (87.4%): Causes skin irritation [Warning Skin corrosion/irritation]

P264, P264+P265, P280, P302+P352, P305+P351+P338, P305+P354+P338, P317, P321, P332+P317, P337+P317, and P362+P364 (click each P-code to see the statement)

Aggregated GHS information provided per 469 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Not Classified

Gefahrenhinweise

Regulatory Information · 4 Einträge

Chemical: Poly(oxy-1,2-ethanediyl), .alpha.-sulfo-.omega.-(dodecyloxy)-, ammonium salt (1:1)

Poly(oxy-1,2-ethanediyl), .alpha.-sulfo-.omega.-(dodecyloxy)-, ammonium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Poly(oxy-1,2-ethanediyl), .alpha.-sulfo-.omega.-(dodecyloxy)-, ammonium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

FRI - indicates a polymeric substance containing no free-radical initiator in its Inventory name but is considered to cover the designated polymer made with any free-radical initiator regardless of the amount used.

Poly(oxyethylene) lauryl ether ammonium sulfate: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Sodium and ammonium laureth sulfate: Human health tier II assessment
Hazards SummaryAn eye irritant; [MSDSonline]
EPA Safer ChemicalChemical: Ammonium Laureth Sulfate

Chemie und Industrie

Pharmakologische Informationen

Metabolism/MetabolitesNitrosamines can enter the body via ingestion, inhalation, or dermal contact. Once in the body, nitrosamines are metabolized by cytochrome P-450 enzymes, which essentially activates them into carcinogens. (A2878, A2879)

Verwendung und Herstellung

Uses · 3 Einträge

CIR ingredient: Ammonium Laureth Sulfate

Used as a foaming and cleansing agent in shampoos and cleaners; [MSDSonline]

Ammonium laureth sulfate is a surfactant often found in shampoos. (L1888)

U.S. Production2022: 11,000 lb
Household ProductsInformation on 205 consumer products that contain Ammonium laureth sulfate in the following categories is provided:
Use Classification · 3 Einträge

EPA Safer Chemical Functional Use Classes -> Surfactants

Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern

Cosmetics -> Foaming; Surfactant; Cleansing

General Manufacturing InformationPoly(oxy-1,2-ethanediyl), .alpha.-sulfo-.omega.-(dodecyloxy)-, ammonium salt (1:1): ACTIVE
Anwendungen · 1 Eintrag

Verwendenammonium laureth sulfate is a surfactant with foaming capabilities. It can also serve as an emulsifying agent and is frequently found in skin cleansers. As a member of the ether sulfate group, it is considered less irritating than its lauryl counterpart, ammonium lauryl sulfate.

Zugehörige Reaktionen

3
Reaktionsaufzeichnung erstellen
Reaktionsgleichung von HRID 265226
HRID 265226als Eduktuspto-grants-1997_07
Reaktionsgleichung von HRID 840338
HRID 840338als Eduktuspto-grants-2002_04
Reaktionsgleichung von HRID 2303752
HRID 2303752als Eduktuspto-grants-2002_08

Notizen zur Verbindung

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Hazard Classes and Categories · 3 Einträge

Skin Irrit. 2 (87.4%)

Not Classified

Acute toxicity - category 4

Toxikologische Informationen

Health EffectsAmmonium laureth sulfate itself only causes mild irritation. However, it may react to produce nitrosamines, which are believed to be carcinogenic. (L1888, L1890)
Exposure RoutesOral (A2880) ; inhalation (A2880) ; dermal (L1889)
Toxicity Summary · 2 Einträge

Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org

While ammonium laureth sulfate itself is not toxic, it is a nitrosating agent. Nitrosating agents may decompose and/or react to cause nitrosamine contamination. Nitrosamines are produced from secondary amines and amides in the presence of nitrite ions and are believed to be carcinogenic. Once in the body, nitrosamines are activated by cytochrome P-450 enzymes. They are then believed to induce their carcinogenic effects by forming DNA adducts at the N- and O-atoms. (L1889, L1890, A2878, A2879, A2880)

Signs and SymptomsAmmonium laureth sulfate can cause mild irritation. (L1888)
Carcinogen ClassificationNot listed by IARC. Certain nitrosamines are classified by IARC as either probably or possibly carcinogenic to humans (Groups 2A and 2B, respectively). (L135)

Sicherheitsdaten

tsca
TSCA listed