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Dimethylsulfon
MSM · METHYL SULFONYL METHANE · METHYL SULFONE · DMSO2 · (CH3)2SO2 · Dimethylsulfon · MethylSulfonylMethane(Msm) · DIMETHYL SULPHONE
Identifikatoren & physikalische Daten
| CAS No. | 67-71-0 |
|---|---|
| Summenformel | C2H6O2S |
| Durchschnittliche Molmasse | 94,14 g/mol |
| Monoisotopische Masse | 94,00885043 g/mol |
| SMILES | CS(C)(=O)=O |
| InChIKey | HHVIBTZHLRERCL-UHFFFAOYSA-N |
| PubChem CID | 6213 |
| ChEMBL | CHEMBL25028 |
| ChEBI | CHEBI:9349 |
| EC No. | 200-665-9 |
| DTXSID | DTXSID4043937 |
| Lokaler Name | Dimethylsulfon |
Chemische & physikalische Eigenschaften
| XLogP | -0,4 |
|---|---|
| Polarare Oberfläche (TPSA) | 42,5 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 5 |
| Formalladung | 0 |
| Komplexität | 85,3 |
| Stoffklassen | Other Classes -> Sulfur Compounds |
| Arzneimittel | Pharmaceuticals -> Listed in ZINC15 |
| Kosmetika | Solvent |
| SpringerMaterials Properties | Schoenflies notation |
| LogP (Verteilungskoeffizient) | -1.41 |
| Dichte | 1.1700 @ 10°C1,16 g/cm3 |
| Dietary Ingredients | Methylsulfonylmethane (MSM) |
| Human Drugs | Breast FeedingLactationMilk, HumanAnti-Inflammatory Agents |
| Siedepunkt | 237.00 to 239.00 °C. @ 760.00 mm Hg238 °C @760 [mm Hg]238 °C (lit.) |
| Schmelzpunkt | 109 °C107-109 °C (lit.) |
| Dampfdruck | 5.15 [mmHg] |
| Physical Description | Dry PowderSolid[Merck Index] White crystalline powderOdorless[Alfa Aesar MSDS] |
| Brechungsindex | 1.4226 |
| Flammpunkt | 290 °F |
| Lagerbedingungen | Store below +30°C. |
| Löslichkeit | 150g/l150 g/L (20 ºC) |
| pKa (Säurekonstante) | 28(at 25℃) |
| Aggregatzustand | Crystals or Crystalline Powder |
| Farbe | White |
| Geruch | at 1.00%. sulfurous burnt |
| Spezifische Wärmekapazität | Cp(gas): 1.06 J/(g·K), at 25℃ |
| Merck | 14,3258 |
| BRN | 1737717 |
| Henry-Konstante | 5.0×10-3 mol/(m3Pa) at 25℃, Mackay et al. (2006) |
| Stabilität | Stable. Combustible. Incompatible with strong oxidizing agents. |
| Kosmetik-Inhaltsstoffe Funktionen | SOLVENTVISCOSITY CONTROLLING |
| InChI | 1S/C2H6O2S/c1-5(2,3)4/h1-2H3 |
| InChIKey | HHVIBTZHLRERCL-UHFFFAOYSA-N |
| SMILES | CS(C)(=O)=O |
| LogP (Verteilungskoeffizient) | -1.074 (est) |
| CAS Datenbank | 67-71-0(CAS DataBase Reference) |
| NIST chemische Informationen | Dimethyl sulfone(67-71-0) |
| EPA chemische Informationen | Dimethyl sulfone (67-71-0) |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 96.1% (122 of 127) of all reports.Not ClassifiedAggregated GHS information provided per 127 reports by companies from 5 notifications to the ECHA C&L Inventory. |
|---|---|
| Regulatorische Informationen | Chemical: Methane, sulfonylbis-Methane, 1,1'-sulfonylbis- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Methane, 1,1'-sulfonylbis- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 04-08-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/17580Dimethyl sulfone: Does not have an individual approval but may be used under an appropriate group standard |
| Gefahrenübersicht | No evidence of teratogenicity in rats[REPROTOX] Not a skin irritantMay cause eye irritation[Alfa Aesar MSDS] See Dimethyl sulfoxide. See Dipropyl sulfone. |
| Hazard Classes and Categories | Not Classified |
| Protective Action Criteria (PAC) | 15 [mg/m3]170 [mg/m3]990 [mg/m3] |
| Effects During Pregnancy and Lactation | ◉ Summary of Use during Lactation |
| Wassergefährdungsklasse (WGK) | 1 |
| TSCA-Inventar-Status | TSCA listed |
| Zollcode | 29309070 |
| RTECS-Nr. | PB2785000 |
| Toxizität | LD50 orally in Rabbit: 17000 mg/kg LD50 dermal Rabbit > 5000 mg/kg |
| Sicherheitshinweise (S) | 22-24/25 |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Verwenden
Dimethyl sulfone is a high tempereture solvent for many inorganic and organic substances,it is used as antiinflammatory, antiproliferative, antiparasitic.