Trisodium citrate｜Huagongshe

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HCID 6224Erstellt: 27. Oktober 2026

Trisodium citrate

trisodium 2-hydroxypropane-1,2,3-tricarboxylate

https://huagongshe.com/de/chemical/6224

Molekülstruktur von Trisodium citrate

Identifikatoren & physikalische Daten

CAS No.	18996-35-5
Summenformel	C6H5Na3O7
Durchschnittliche Molmasse	258,07 g/mol
Monoisotopische Masse	257,97283534 g/mol
SMILES	O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].[Na+].[Na+].[Na+]
InChIKey	HRXKRNGNAMMEHJ-UHFFFAOYSA-K
PubChem CID	6224
ChEMBL	CHEMBL1355
ChEBI	CHEBI:53258
EC No.	200-675-3
DTXSID	DTXSID2026363

Chemische & physikalische Eigenschaften

Polarare Oberfläche (TPSA)	141
H-Brücken-Donoren	1
H-Brücken-Akzeptoren	7
Frei drehbare Bindungen	2
Schwere Atome	16
Formalladung	0
Komplexität	211
Stoffklassen	Metals -> Organic Acids, Metal Salts
Kosmetika	Cosmetic ingredients (Sodium Citrate) -> CIR (Cosmetic Ingredient Review)BufferingChelating
pH	Between 7,5 and 9,0 (5 % aqueous solution)
Duftstoffe	Fragrance Ingredient (Sodium citrate) -> IFRA transparency List
Lebensmittelzusatzstoffe	COLOR OR COLORING ADJUNCT, EMULSIFIER OR EMULSIFIER SALT, FLAVORING AGENT OR ADJUVANT, MALTING OR FERMENTING AID, NUTRIENT SUPPLEMENT, PH CONTROL AGENT, SEQUESTRANT, STABILIZER OR THICKENER, SURFACE-ACTIVE AGENT -> FDA Substance added to food
Löslichkeit	29.4g/LWhite, odorless crystals, granules or powdercool, saline taste. Stable in airbecomes anhydrous at 150 °C. Sol in 1.3 parts water, 0.6 part boiling water. Insol in alcohol. The aqueous soln is slightly alkaline to litmuspH about 8/Dihydrate/Solubility in water, g/100ml at 25 °C: 42.5
Human Drugs	FDA approved drugs -> Active ingredient
Animal Drugs	Pharmaceuticals -> UK Veterinary Medicines Directorate List
Siedepunkt	BP: Decomposes at red heat /Dihydrate/
Schmelzpunkt	>300 °C
Food Contact Substances	FCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR
Physical Description	CBILarge CrystalsOther SolidDry PowderLiquidCrystalline white powder or colourless crystalsWhite solid[ICSC]White odorless solid[JECFA] White crystalline powder[Alfa Aesar MSDS]WHITE GRANULES OR POWDER.

Sicherheit & Vorschriften

GHS-Einstufung	This chemical does not meet GHS hazard criteria for 94.3% (1117 of 1184) of all reports.Not ClassifiedAggregated GHS information provided per 1184 reports by companies from 9 notifications to the ECHA C&L Inventory.This chemical does not meet GHS hazard criteria for 27.7% (41 of 148) of reports.WarningH319 (72.3%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
Regulatorische Informationen	Chemical: 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium saltChemical: 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt (1:3) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt (1:3) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 02-05-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/15303Trisodium citrate: Does not have an individual approval but may be used under an appropriate group standard1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Weitere Sicherheitsinformationen	IMAP assessments - 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt: Environment tier I assessmentIMAP assessments - 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt: Human health tier I assessment
Brandgefahren	Combustible.
Gefahrenübersicht	Emergency treatment: symptomatic drug ingestion[HSDB] An eye and respiratory tract irritant[ICSC] May cause irritation[MSDSonline] See Citric acid.Causes convulsions in intraperitoneal lethal-dose studies of mice and rats[RTECS] Acceptable daily intake (ADI) as food additive not limited

FDA-Anforderungen

Manufacturers, packers, and distributors of drug and drug products for human use are responsible for complying with the labeling, certification, and usage requirements as prescribed by the Federal Food, Drug, and Cosmetic Act, as amended (secs 201-902, 52 Stat. 1040 et seq., as amended21 U.S.C. 321-392).Trisodium citrate is a prior sanctioned food ingredient classified as a stabilizer when migrating from food-packaging material.

Erste-Hilfe-Maßnahmen	Fresh air, rest.Rinse and then wash skin with water and soap.First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.Rinse mouth.

Entsorgungsverfahren	SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Toxizitätsübersicht	Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org

Non-Human Toxicity Excerpts	NO TERATOGENIC EFFECTS WERE OBSERVED IN SINGLE-COMB WHITE LEGHORN CHICK EMBRYOS AFTER 10.00 MG/EGG SODIUM CITRATE (DISSOLVED IN WATER) WAS INJECTED INTO AIR CELL AT 96 HR OF INCUBATION.