Grundinformationen
- CAS
68-36-0- Standard-SMILES
ClC(Cl)(Cl)c1ccc(C(Cl)(Cl)Cl)cc1- InChIKey
OTEKOJQFKOIXMU-UHFFFAOYSA-N- Summenformel
- C8H4Cl6
- Durchschnittliche Molmasse
- 312,8 g/mol
- Monoisotopische Masse
- 309,844416
Überblick
structure
Namen und Bezeichner
- Bevorzugter Name
- 1,4-Bis(trichloromethyl)benzene
- IUPAC
- 1,4-bis(trichloromethyl)benzene
- Lokaler Name
- 1,4-Bis(trichlormethyl)benzol
- Englischer Name
- 1,4-Bis(trichloromethyl)benzene
- Summenformel
- C8H4Cl6
- Molmasse
- 312.84
Namen und Synonyme
1,4-BIS(TRICHLOROMETHYL)BENZENE68-36-0BitribenChloksilChloxilChloxylHexicholKhloxilCloxilHetolHexachloroparaxylolKhloksil
Weitere Namen anzeigen
P303
hexachloroparaxyleneBenzene, 1,4-bis(trichloromethyl)-1,4-Di(trichloromethyl)benzenep-Bis(perchloromethyl)benzenep-Bis(trichloromethyl)benzenealpha,alpha,alpha,alpha',alpha',alpha'-Hexachloro-p-xylenep-Di(trichloromethyl)benzeneHexachloro-4-xylene
Datenbank-Bezeichner
- CAS
68-36-0- PubChem CID
- 6233
- DTXSID
DTXSID7026366- ChEMBL
CHEMBL3182002- UNII
- 42CH2735EU
- EC Number
- 200-686-3
- Nikkaji
- J1.419B
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 4,6
- Polarare Oberfläche (TPSA)
- 0 Ų
- H-Brücken-Donoren
- 0
- H-Brücken-Akzeptoren
- 0
- Frei drehbare Bindungen
- 0
- Schwere Atome
- 14
- Formalladung
- 0
- Komplexität
- 161
Experimentelle und physikochemische Eigenschaften
SpringerMaterials PropertiesNuclear quadrupole resonance spectroscopy
PesticidesPesticides -> Organochlorine Pesticides
LogP4.62
Color/FormCRYSTALS FROM HEXANE OR ETHER
Melting Point108-110 °C
Vapor Pressure0.00102 [mmHg]
Physical DescriptionSolid; [Merck Index] Slightly yellow fine crystals; [MSDSonline]
Physikochemische Eigenschaften
- Schmelzpunkt
- 106 · 106-110 °C
- Siedepunkt
- 312 °C · 312 °C
- Dichte
- 1.6957 · 1.6957 (rough estimate)
- Brechungsindex
- 1.584 · 1.5840 (estimate)
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Danger
H301 (25%): Toxic if swallowed [Danger Acute toxicity, oral]
P260, P261, P262, P264, P264+P265, P270, P271, P280, P301+P316, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P361+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 4 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Hazards SummaryAn irritant; [MSDSonline]
Hazard Classes and CategoriesSkin Corr. 1C (100%)
Toxikologische Informationen
InteractionsVET: POSSIBLE INCOMPATIBILITY WITH ACID FOODSTUFFS, ACID SILAGE, FRESH BEETS, & CABBAGE. KEEP LIVESTOCK OFF THESE FEEDS FOR 1 DAY BEFORE & 3 DAYS AFTER WORMING.
Adverse EffectsOther Poison - Organochlorine
Non-Human Toxicity Excerpts
P-BIS(TRICHLOROMETHYL)BENZENE 100 MG/KG ORALLY DAILY FOR 4 WK IN RATS INCR BODY WT OF 6 OUT OF 7, HAD NO EFFECT ON LIVER OR KIDNEY; 200 MG/KG KILLED 1 & DECR BODY WT & CAUSED VACUOLIZATION OR FATTY DEGENERATION IN LIVER & KIDNEY OF 2 OUT OF 9 RATS.
P-BIS(TRICHLOROMETHYL)BENZENE 300 MG/KG ORALLY & DAILY FOR 4 WK TO RATS INCR BODY WT OF 7 OUT OF 8, HAD NO EFFECT ON LIVER OR KIDNEY, 500 MG/KG DECR BODY WT & CAUSED DEATH IN 3 OUT OF 8 AFTER 8TH, 21ST, & 27TH DOSE. LIVER & KIDNEY SHOWED FATTY DEGENERATION.
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
Agents that kill parasitic worms. They are used therapeutically in the treatment of HELMINTHIASIS in man and animal.
Agents used to treat cestode, trematode, or other flatworm infestations in man or animals.
Absorption, Distribution and ExcretionHEXACHLORO-P-XYLENE RESIDUES WERE HIGH IN MILK AFTER ADMIN OF AGRAMED NEU TO CATTLE. HEXACHLORO-P-XYLENE WAS LIPOPHILIC AND STABLE. RESIDUES AVERAGED 10 MG/KG ON 2ND DAY AFTER TREATMENT & 0.1 MG/KG 40 DAYS AFTER TREATMENT.
Verwendung und Herstellung
Uses
Used as insecticide and veterinary anthelmintic (trematodes); [Merck Index]
Farming (Pesticides) [Category: Industry]
INSECTICIDE; FASCIOLICIDE
MEDICATION (VET)
Methods of ManufacturingUSUALLY OBTAINED BY PHOTOCHLORINATION OF PARA-XYLENE: MCBEE ET AL, IND ENG CHEM 39, 298 (1947)...LIGETT, US PATENT 2,654,789 (1953 TO ETHYL CORP).
General Manufacturing InformationBenzene, 1,4-bis(trichloromethyl)-: ACTIVE
Vor- und nachgelagerte Produkte
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