Grundinformationen
- Standard-SMILES
CC(O)C(=O)[O-].[NH4+]- InChIKey
RZOBLYBZQXQGFY-UHFFFAOYSA-N- Summenformel
- C3H6O3.H3N
- Durchschnittliche Molmasse
- 107,11 g/mol
- Monoisotopische Masse
- 107,05824315
Überblick
Ammonium lactate appears as white solid or liquid. Has no odor. Sinks and mixes with water. (USCG, 1999)
Namen und Bezeichner
- Bevorzugter Name
- Ammonium Lactate
- IUPAC
- azanium 2-hydroxypropanoate
- Lokaler Name
- Ammoniumlactat
- Englischer Name
- Ammonium Lactate
- Summenformel
- C3H9NO3
- Molmasse
- 107.11
Namen und Synonyme
Weitere Namen anzeigen
Datenbank-Bezeichner
- CAS
515-98-0、52003-58-4- PubChem CID
- 62358
- DTXSID
DTXSID3052808- ChEMBL
CHEMBL1200747- UNII
- 67M901L9NQ
- EC Number
- 208-214-8、856-973-4
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 61,4 Ų
- H-Brücken-Donoren
- 2
- H-Brücken-Akzeptoren
- 3
- Frei drehbare Bindungen
- 0
- Schwere Atome
- 7
- Formalladung
- 0
- Komplexität
- 53,5
Experimentelle und physikochemische Eigenschaften
Cosmetics
Cosmetic ingredients (Ammonium Lactate) -> CIR (Cosmetic Ingredient Review)
Buffering
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
Physical Description
Ammonium lactate appears as white solid or liquid. Has no odor. Sinks and mixes with water. (USCG, 1999)
Liquid; Liquid; Other Solid
White solid or liquid; Odorless; [CHRIS] 68-72% Aqueous solution: Light yellow liquid; [PURAC Bioquimica MSDS]
Physikochemische Eigenschaften
- Schmelzpunkt
- 91 · 91-94 °C
- Siedepunkt
- 74 °C · 74 °C(Press: 0.14 Torr)
- Dichte
- 1.054 g/mL · 1.054 g/mL at 25 °C
- Brechungsindex
- 20 · n20/D 1.363
- storage temp.
- -20 °C · Store at -20°C
- Aggregatzustand
- Liquid
- Farbe
- Colorless to light yellow
- PH
- 6.58 · 6.58(1 mM solution);6.56(10 mM solution);6.55(100 mM solution);6.5(1000 mM solution)
- Wasserlöslichkeit
- 125 mg/mL · Water: 125 mg/mL (1167.02 mM)
- Kosmetik-Inhaltsstoffe Funktionen
- SKIN CONDITIONINGKERATOLYTICHUMECTANTBUFFERING
- InChI
- InChI=1S/C3H6O3.H3N/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);1H3
- InChIKey
- RZOBLYBZQXQGFY-UHFFFAOYSA-N
- SMILES
- [NH4+].C([O-])(=O)C(C)O
- CAS Datenbank
- 515 · 515-98-0(CAS DataBase Reference)
- EPA chemische Informationen
- Ammonium lactate (515-98-0)
Sicherheit und Regulatorisches
GHS-Klassifizierung
GHS Classification
This chemical does not meet GHS hazard criteria for 87.6% (415 of 474) of all reports.
Warning
H315 (12.2%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 474 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Warning
Gefahrenhinweise
Regulatory Information
Chemical: Propanoic acid, 2-hydroxy-, monoammonium salt
Propanoic acid, 2-hydroxy-, ammonium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Propanoic acid, 2-hydroxy-, ammonium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Ammonium lactate: Does not have an individual approval but may be used under an appropriate group standard
Hazards Summary
Causes tremors, muscle weakness, and altered gastric secretion in acute oral studies of cattle; [RTECS] A skin, eye, nose, and throat irritant; Harmful by ingestion; [CHRIS] Not to be used in infant foods; [JECFA] Not considered to pose any health hazards; [PURAC Bioquimica MSDS]
Reactivity Profile
Acidic salts, such as AMMONIUM LACTATE, are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions.
Hazard Classes and Categories
Skin Irrit. 2 (12.2%)
Eye Irrit. 2 (100%)
Sicherheit und Schutzausrüstung
Protective Action Criteria (PAC)
12 [mg/m3]
130 [mg/m3]
790 [mg/m3]
Toxikologische Informationen
Toxicity Summary
Based on the available information included in this report, the CIR Expert Panel concludes that Glycolic and Lactic Acid, their common salts and their simple esters, are safe for use in cosmetic products at concentrations less than or equal to 10%, at final formulation pH greater than or equal to 3.5, when formulated to avoid increasing sun sensitivity or when directions for use include the daily use of sun protection. These ingredients are safe for use in salon products at concentrations less than or equal to 30%, at final formulation pH greater than or equal to 3.0, in products designed for brief, discontinuous use followed by thorough rinsing from the skin, when applied by trained professionals, and when application is accompanied by directions for the daily use of sun protection...Ammonium Lactate...
Safe for use in cosmetics, with qualifications
Sicherheitsdaten
- wgk
- -
- tsca
- TSCA listed
- Speicherklasse
- 10 - Combustible liquids
Chemie und Industrie
Pharmakologische Informationen
Pharmacodynamics
Lactic acid is an alpha-hydroxy acid. It is a normal constituent of tissues and blood. The alpha-hydroxy acids (and their salts) may act as humectants when applied to the skin. This property may influence hydration of the stratum corneum. In addition, lactic acid, when applied to the skin, may act to decrease corneocyte cohesion.
FDA Pharmacological Classification
67M901L9NQ
AMMONIUM LACTATE
Established Pharmacologic Class [EPC] - alpha-Hydroxy Acid
Chemical Structure [CS] - Hydroxy Acids
Ammonium lactate is an alpha-Hydroxy Acid.
AMMONIUM LACTATE
Verwendung und Herstellung
Uses
CIR ingredient: Ammonium Lactate
Permitted for use as an inert ingredient in non-food pesticide products; [EPA] Used in skin moisturizers; [ExPub: TERIS] Used to regulate acidity in foods and to treat flour; [JECFA] Used as an additive to cosmetics and specialty chemical; [PURAC Bioquimica MSDS]
Use Classification
Food Additives -> ACIDITY_REGULATOR; FLOUR_TREATMENT_AGENT -> JECFA Functional Classes
Cosmetics -> Buffering
General Manufacturing Information
All Other Chemical Product and Preparation Manufacturing
Propanoic acid, 2-hydroxy-, ammonium salt (1:1): ACTIVE
Anwendungen
BeschreibungAmmonium lactate is a compound with formula NH4(C2H4(OH)COO). It is the ammonium salt of lactic acid. It has E number "E328" and is the active ingredient of the skin lotions Amlactin and Lac-Hydrin.
VerwendenWhen ammonium lactate is applied topically, it is found to thicken the viable epidermis while reducing the thickness of the stratum corneum layer. It is a neutralized version of lactic acid.
Vor- und nachgelagerte Produkte
Nachgelagerte Produkte
Anbieter50 Anbieter
Zugehörige Reaktionen
Verknüpfte Notizen
Wird geladen…