HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Benziodaron
l2329 · Dilaf · algocor · Vasilar · carofam · Corofam · amplivix · cardivix
Identifikatoren & physikalische Daten
| CAS No. | 68-90-6 |
|---|---|
| Summenformel | C17H12I2O3 |
| Durchschnittliche Molmasse | 518,08 g/mol |
| Monoisotopische Masse | 517,88759 g/mol |
| SMILES | CCc1oc2ccccc2c1C(=O)c1cc(I)c(O)c(I)c1 |
| InChIKey | CZCHIEJNWPNBDE-UHFFFAOYSA-N |
| PubChem CID | 6237 |
| ChEMBL | CHEMBL232201 |
| ChEBI | CHEBI:135814 |
| EC No. | 200-695-2 |
| DTXSID | DTXSID1046134 |
| Lokaler Name | Benziodaron |
Chemische & physikalische Eigenschaften
| XLogP | 5,6 |
|---|---|
| Polarare Oberfläche (TPSA) | 50,4 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 3 |
| Frei drehbare Bindungen | 3 |
| Schwere Atome | 22 |
| Formalladung | 0 |
| Komplexität | 405 |
| Endocrine Disruptors | Potential endocrine disrupting compound |
| Schmelzpunkt | 167° |
| Dichte | 1.9173 (estimate) |
| Lagerbedingungen | Refrigerator |
| Löslichkeit | Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)5.881mg/L(20 ºC) |
| Aggregatzustand | Solid |
| Farbe | Beige |
| CAS Datenbank | 68-90-6 |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement)The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory. |
|---|---|
| Weitere Sicherheitsinformationen | IMAP assessments - Methanone, (2-ethyl-3-benzofuranyl)(4-hydroxy-3,5-diiodophenyl)-: Human health tier I assessment |
| Hazard Classes and Categories | Acute Tox. 3 (100%) |
| Drug Induced Liver Injury | Drug Induced Liver Injury Rank (DILIrank 2.0)BenziodaronevMost-DILI-concern8WithdrawnDOI:10.1016/j.drudis.2016.02.015 |
| Zollcode | 2906.19.5000 |
Anwendungen & Verwendung
Verwenden
Benziodarone is a uricosuric drug,it is used to effectively to control hyperuricemia in renal transplantation.